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27篇 您的检索式：作者名="Petrtyl"

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	题名	作者	年代	出处	被引量
1	Osteopontin: A non-invasive parameter of portal hypertension and prognostic marker of cirrhosis显示文摘AIM: To investigate the relationship between osteopontin plasma concentrations and the severity of portal hypertension and to assess osteopontin prognostic value.METHODS: A cohort of 154 patients with confirmed liver cirrhosis(112 ethylic, 108 men, age 34-72 years)were enrolled in the study. Hepatic venous pressure gradient(HVPG) measurement and laboratory and ultrasound examinations were carried out for all patients. HVPG was measured using a standard catheterization method with the balloon wedge technique. Osteopontin was measured using the enzyme-linked immunosorbent assay(ELISA) method in plasma. Patients were followed up with a specific focus on mortality. The control group consisted of 137 healthy age- and sex- matched individuals.RESULTS: The mean value of HVPG was 16.18 ± 5.6 mm Hg. Compared to controls, the plasma levels of osteopontin in cirrhotic patients were significantly higher(P < 0.001). The plasma levels of osteopontin were positively related to HVPG(P = 0.0022, r = 0.25) and differed among the individual Child-Pugh groups of patients. The cut-off value of 80 ng/m L osteopontin distinguished patients with significant portal hypertension(HVPG above 10 mm Hg) at 75% sensitivity and 63% specificity. The mean follow-up of patients was 3.7 ± 2.6 years. The probability of cumulative survival was 39% for patients with HVPG > 10 mm Hg and 65% for those with HVPG ≤ 10 mm Hg(P = 0.0086, odds ratio(OR), 2.92, 95% confidence interval(CI): 1.09-7.76). Osteopontin showed a similar prognostic value to HVPG. Patients with osteopontin values above 80 ng/m L had significantly lower cumulative survival compared to those with osteopontin ≤ 80 ng/m L(37% vs 56%, P = 0.00035; OR = 2.23, 95%CI: 1.06-4.68).CONCLUSION: Osteopontin is a non-invasive parameter of portal hypertension that distinguishes patients with clinically significant portal hypertension. It is a strong prognostic factor for survival.	Radan Bruha Marie Jachymova Jaromir Petrtyl Karel Dvorak Martin Lenicek Petr Urbanek Tomislav Svestka Libor Vitek	2016	World Journal of Gastroenterology2016，22，12：	20
2	Long term pharmacological treatment of portal hypertension显示文摘	Bruha R Petrtyl J Urbanek P	2005	Cas LEK Cesk2005，144，：	1
3	Endoscopic variceal band ligation compared with propranolol for prophylaxis of first variceal bleeding显示文摘	Drastich P Lata J Petrtyl J	2011	Ann Hepatol2011，10，2：	1
4	Endoscopic variceal band ligation compared with propranolol for prophylaxis of first varical bleeding显示文摘	DRASTICH P LATA J PETRTYL J	2011	Ann Hepatol2011，10，6：	1
5	Endoscopic variceal band ]igation compared with propranolol for prophylaxis of first variceal bleeding 显示文摘	Drastich P Lata J Petrtyl J	2011	Ann Hepatol2011，10，2：	1
6	Effect of carvedilol on portal hypertension depends on the degree of endothelial activation and inflammatory changes显示文摘	BRUHA R VITEK L PETRTYL J	2006	Scand J Gastroen- terol2006，41，12：	1
7	Intraluninal brachytherapy and selfexpandable stents in nonresectable billary malignancies - the question of long - term paliation 显示文摘	Bruha R Petrtyl J Kubecova M	2001	Hepatogastroenterology2001，18，39：	1
8	Intraluminal brachytherapy and selfexpand-able stents in nonresectable biliaty malignancies - - the question of long- term palliation显示文摘	Bruha R Petrtyl J Kubecova M	2001	Hepatogasroenterology2001，48，39：	1
9	Endoscopic variceal band ligation compared with propranolol for prophylaxis of first variceal bleeding显示文摘	Drastich P Lata J Petrtyl J	2011	Ann Hepatol2011，10，6：	1
10	Endoscopic variceal band ligation compared with propranolol for prophylaxis of first variceal bleeding显示文摘	Drastich P Lata J Petrtyl J		0，，：	1
11	Intraluminal brachytherapy and selfexpandable stents in nonresectable biliary malignancies-the question of long - term palliation 显示文摘	Bruha R Petrtyl J Kubecova M	2001	Hepatogastroenterology2001，48，：	1
12	Effect of carvedilol on portal hypertension depends on the degree of endothelial activation and inflammatory changes显示文摘	BRUHA R VITEK L PETRTYL J	2006	Scand J Gastroenterol2006，41，12：	1
13	Spatial organization of the hav- ersian bone in man 显示文摘	Petrtyl M Hert J Fiala P	1996	J Biomech1996，29，：	1
14	Management of benign intrahepatic bile duct strictures : initial experience with polydioxanone biodegradable stents 显示文摘	Petrtyl J Bruha R Horak L	2010	Endoscopy2010，422，：	1
15	Trefoil factor family (TFF) proteins as potential serum biomarkers in patients with metastatic eoloreetal cancer显示文摘	Voeka M Langer D Petrtyl J	2015	Neoplasma2015，62，47：	1
16	Intraluminal brachytherapy and selfexpandable stents in nonreseetable biliary malignancies-the question of long-term palliation显示文摘	Bruha R Petrtyl I Kubeeova M	2001	Hepa Togastroenterology2001，48，39：	1
17	Intraluminal brachytherapy and selfexpandable stents in nonrescetable biliary malignancies the question of long-trem palliation显示文摘	Bruha R Petrtyl J Kubeeova M	2001	Hepato-Gastroenterology2001，48，69：	1
18	Tumor markers in the diagnois tumors in the subhepatic area显示文摘	Dufek V Petrtyl J Klener P	1994	Vnitr Lek1994，40，6：	1
19	Endoscopic variceal band ligation compared with propranolol for prophylaxis of first variceal bleeding显示文摘	DRASTICH P LATA J PETRTYL J BRUHA R PROCHAZKA V VANASEK T	2011	Ann Hepatol2011，10，：	1
20	The initial beating capacities of subchondral bone replacements considerably contributing to chondrogenesis显示文摘	Petrtyl M Danesova J Lisal J	2010	Acta Bioeng Biomech2010，12，3：	1

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