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| 1 | Mitochondrial metabolism in regulating macrophage polarization:an emerging regulator of metabolic inflammatory diseases显示文摘As a major type of immune cells with heterogeneity and plasticity,macrophages are classically divided into inflammatory(M1)and alternative/anti-inflammatory(M2)types and play a crucial role in the progress of the inflammatory diseases.Recent studies have shown that metabolism is an importa nt determ inant of macrophage phe no type.Mitoch on dria,one of the most importa nt compartments involving cell metabolism,are closely associated with the regulation of cell functions.In most types of cell,mitochondrial oxidative phosphorylation(OXPHOS)is the primary mode of cellular energy production.However,mitochondrial OXPHOS is inhibited in activated M1 macrophages,ren deri ng them un able to be converted into M2 phe no type.Thus,mitochondrial metabolism is a crucial regulator in macrophage functions.This review summarizes the roles of mitochondria in macrophage polarization and analyzes the molecular mechanisms underlying mitochondrial metabolism and function,which may provide new approaches for the treatment of metabolic inflammatory diseases. | Jina Qing Zizhen Zhang Petr Novak Guojun Zhao Kai Yin | 2020 | Acta Biochimica et Biophysica Sinica2020,52,9: | 5 |
| 2 | Safety aspects of graphite negative electrode materials for lithium- ion batteries显示文摘 | Felix Joho Petr Novak Michael E Spahr | 2002 | Electrochem Soc2002,149,: | 1 |
| 3 | Characterization of Hepatocellular Carcinoma Related Genes and Metabolites in Human Nonalcoholic Fatty Liver Disease显示文摘 | John D. Clarke Petr Novak April D. Lake Petia Shipkova Nelly Aranibar Donald Robertson Paul L. Severson Michael D. Reily Bernard W. Futscher Lois D. Lehman-McKeeman Nathan J. Cherrington | 2014 | Digestive Diseases and Sciences2014,,2: | 1 |
| 4 | Electrochemlcally active polymers for rechargeable batteries 显示文摘 | Novak Petr Muller Klaus Santhanam K S V | 1997 | Chem Rev1997,97,: | 1 |
| 5 | In stiu-investigation of the electroche mical react ion of carbonate electrolyte solutions at graphite electrodes显示文摘 | Roman Imhof Petr Novak | 1998 | J Electroche m Soc1998,145,4: | 1 |
| 6 | Dielectric behaviors at microwave frequencies and Mssbauer effects of chalcedony, agate, and zultanite显示文摘In this study, dielectric properties within 8–12 GHz microwave frequencies, inductively coupled plasma-atomic emission spectrometry, Fourier transform infrared spectrometry, synchronized two thermal analyses, and57 Fe Mossbauer spectroscopy analysis of chalcedony, agate, and zultanite samples from Turkey are presented. Agate and chalcedony show the same nine vibrational absorption peaks obtained unlike zultanite from FTIR spectra in the 350 cm-1to 4000 cm-1range,εvalues of chalcedony, agate and zultanite derived at 10.5 GHz were 4.67, 4.41, and 7.34, respectively, εand ε values of the studied samples at the microwave frequencies are related to the percentage weight of their constituent parts in their chemical compositions.57 Fe Mossbauer spectroscopy results confirm the existence of iron-containing islands in the crystal structure of zultanite, agate, and chalcedony samples, equipped them with magnetic features typical for magnetic nanoparticles including superparamagnetism. The presence of iron-containing islands significantly affects the magnetic, dielectric,and optical properties of studied samples that are not observed for pure minerals without any foreign inclusions. | Levent Paral? Israfil Sabikoglu Jiri Tucek Jiri Pechousek Petr Novak Jakub Navarik | 2015 | Chinese Physics B2015,24,5: | 0 |
| 7 | Antibacterial properties of lucifensin in Lucilia sericata maggots after septic injury显示文摘Objective:To investigate the antibacterial properties of lucifensin in maggots of IjicUia sericala after septic injury.Mettiods:In our preliminary study we have shown that injuring the maggots with a needle soaked in lipopolysaccharide solution induced within 24 h lucifensin expression in the fat body and in the grease coupler of the salivary glands.It is assumed that lucifensin is secreted solely from this tissue into the haemoiymph(similar to other insect defensins) and not into secreted/excreted products.We used high-performance liquid chromatography fractionation and radial diffusion assay to investigate the antibacterial properties of haemoiymph extracted from larvae after septic injury.Results:After septic injury,production of lucifensin in the haemoiymph is increased.This led to higher antibacterial activity of such haemoiymph in comparison to non-stimulated larvae.Coclusions:These results suggest that beside the previously demonstrated role of lucifensin in the debridement therapy,lucifensin is simultaneously important as a part of the systematic immune response. | Ivana Valachova Emanuel Prochazka Jana Bohova Petr Novak Peter Takac Juraj Majtan | 2014 | Asian Pacific Journal of Tropical Biomedicine2014,4,5: | 0 |
| 8 | The effect of neodymium substitution on the structural and magnetic properties of nickel ferrite显示文摘Nickel ferrite Ni Fe2O4 is a typical soft magnetic ferrite with high electrical resistivity used as high frequency magnetic material. Neodymium(Nd3+) doped Ni Fe2O4 materials were fabricated using solid state reaction. The properties of the obtained material were investigated by X-Ray Diffraction(XRD), Scanning Electron Microscope(SEM), Fourier-Transform Infrared Spectroscopy(FT-IR), magnetic measurements on SQUID and M?ssbauer spectroscopy. It was found that the material consists of two different phases: Nd3+doped Ni Fet2O4and Nd Fe O3. The Nd3 ions occupy cation sites of the Ni Fe2O4 inverse spinel structure. NdFeO3 phase occurred when the level of Nd3+atoms exceed a percolation limit.The presence of both phases was confirmed by SEM observations. The M?ssbauer spectra analysis showed two sextets, which can be ascribed to iron atoms in tetrahedral and octahedral positions. From their intensities it is concluded that Nd3+occupies octahedral sites in the spinel structure of Ni Fe2O4, which were originally occupied by Ni2+. | Israfil Sabikoglu Levent Parali Ondrej Malina Petr Novak Josef Kaslik Jiri Tucek Jiri Pechousek Jakub Navarik Oldrich Schneeweiss | 2015 | Progress in Natural Science:Materials International2015,25,3: | 0 |