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| 1 | Neo-adjuvant chemo(radio)therapy in gastric cancer: Current status and future perspectives显示文摘In the last 20 years, several clinical trials on neoadjuvant chemotherapy and chemo-radiotherapy as a therapeutic approach for locally advanced gastric cancer have been performed. Even if more data are necessary to define the roles of these approaches, the results of preoperative treatments in the combined treatment of gastric adenocarcinoma are encouraging because this approach has led to a higher rate of curative surgical resection. Owing to the results of most recent randomized phase III studies, neoadjuvant chemotherapy for locally advanced resectable gastric cancer has satisfied the determination of level I evidence. Remaining concerns pertain to the choice of the optimal therapy regimen, strict patient selection by accurate pre-operative staging, standardization of surgical procedures, and valid criteria for response evaluation. New well-designed trials will be necessary to find the best therapeutic approach in pre-operative settings and the best way to combine old-generation chemotherapeutic drugs with new-generation molecules. | Alberto Biondi Maria C Lirosi Domenico D'Ugo Valeria Fico Riccardo Ricci Francesco Santullo Antonia Rizzuto Ferdinando CM Cananzi Roberto Persiani | 2015 | World Journal of Gastrointestinal Oncology2015，7，12： | 13 |
| 2 | R0 resection in the treatment of gastric cancer:Room for improvement显示文摘Gastric carcinoma is one of the most frequent malignancies in the world and its clinical behavior especially depends on the metastatic potential of the tumor.In particular,lymphatic metastasis is one of the main predictors of tumor recurrence and survival,and current pathological staging systems reflect the concept that lymphatic spread is the most relevant prognostic factor in patients undergoing curative resection.This is compounded by the observation that two-thirds of gastric cancer in the Western world presents at an advanced stage,with lymph node metastasis at diagnosis.All current therapeutic efforts in gastric cancer are directed toward individualization of therapeutic protocols,tailoring the extent of resection and the administration of preoperative and postoperative treatment.The goals of all these strategies are to improve prognosis towards the achievement of a curative resection(R0 resection) with minimal morbidity and mortality,and better postoperative quality of life. | Alberto Biondi Roberto Persiani Ferdinando Cananzi Marco Zoccali Vincenzo Vigorita Andrea Tufo Domenico D'Ugo | 2010 | World Journal of Gastroenterology2010，16，27： | 4 |
| 3 | Preoperative chemotherapy in gastric cancer: expanding the indications, limiting the overuse显示文摘 | Ferdinando C. M. Cananzi Alberto Biondi Luca Cozzaglio Domenico D’Ugo Roberto Persiani Vittorio Quagliuolo | 2015 | Gastric Cancer2015，，1： | 2 |
| 4 | Response to neoadjuvant chemotherapy and effects of tumor regression in gastric cancer显示文摘 | D. D’Ugo R. Persiani S. Rausei A. Biondi V. Vigorita S. Boccia R. Ricci | 2006 | European Journal of Surgical Oncology2006，，10： | 2 |
| 5 | Preoperative treatment and surgery in gastric cancer: friends or foes?显示文摘 | Domenico D’Ugo Stefano Rausei Alberto Biondi Roberto Persiani | 2009 | Lancet Oncology2009，，2： | 2 |
| 6 | Immediately preoperative laparoscopic staging for gastric cancer显示文摘 | Coppola R Persiani R | 1996 | Surg Endosc1996，10，： | 1 |
| 7 | The risk of biliary ductal injury during laparoscopic cholecystectomy显示文摘 | Nuzzo G Giuliante F Persiani R | 2004 | J Chir (Paris)2004，141，6： | 1 |
| 8 | The risk of biliary duetal injury during laparoscopic cholecystectomy 显示文摘 | Nuzzo GD Giuliante F Persiani R | 2004 | J Chit ( Paris )2004，141，6： | 1 |
| 9 | Solfotransferase 1 A1 Polymorphism and gastric cancer risk : a pibtcase - control study 显示文摘 | Boccia S Persiani R La Tone G | 2005 | Cancer Lett2005，229，2： | 1 |
| 10 | Sulfotransferase 1A1 polymorphism and gastric cancer risk: a pilot case -control study 显示文摘 | Boccia S Persiani R La Torre G | 2005 | Cancer Lett2005，229，2： | 1 |
| 11 | The risk of biliary ductal injury during laparoscopic cholecystectomy 显示文摘 | Nuzzo G Giuliante F Persiani R | 2004 | J Chir ( Paris)2004，141，6： | 1 |
| 12 | Pharmacokinetic profile of dexloxiglumide 显示文摘 | PERSIANI S D' AMATO M JAKATE A | 2006 | Clin Pharmacokinet2006，45，12： | 1 |
| 13 | A case-control study comparing methylene blue directed biopsies and random biopsies for detecting pre-cancerous lesions in the follow-up of gastric cancer patients显示文摘 | Ojetti V Persiani R Nista EC | 2007 | Eur Rev Med Pharmacol Sci2007，11，5： | 1 |
| 14 | Crystalline glucosamine sulfate in the management of knee osteoarthritis: efficacy, safety, and pharmacokinetic properties显示文摘 | Rovati LC Girolami F Persiani S | 2012 | Ther Adv Musculoskelet Dis2012，4，3： | 1 |
| 15 | Neoadjuvant chemotherapy in gastric carcinoma显示文摘 | D Ugo D Persiani R Pende V | 2001 | Ann Ital Chir2001，72，1： | 1 |
| 16 | T-downstaging after neoadjuvant chemotherapy in locally advanced gastric carcinoma显示文摘 | Persiani R D′Ugo D Biondi A | 2005 | Suppl Tumori2005，4，3： | 1 |
| 17 | Glucosamine oral bioavailability and plasma pharmacokinetics after increasing doses of crystalline glucosamine sulfate in man显示文摘 | Persiani S Roda E Rovati LC | 2005 | Osteoarthritis Cartilage2005，13，12： | 1 |
| 18 | Neoadjuvant chemotherapy in gastric carcinoma显示文摘 | D' Ugo D Persiani R Pende V | 2001 | Ann Ital Chir2001，72，1： | 1 |
| 19 | Solfotransferase 1A1 Polymorphism and gastric cancer risk: a pibtcase-control study 显示文摘 | Boccia S Persiani R La Tone G | 2005 | Cancer Lett2005，229，2： | 1 |
| 20 | Synovial and plasma glucosamine concentrations in osteoarthritic patients following oral crystalline glucosamine sulphate at therapeutic dose显示文摘 | Persiani S Rotini R Trisolino G | 2007 | Osteoarthritis Cartilage2007，15，7： | 1 |
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