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| 1 | OsbZIP60-mediated unfolded protein response regulates grain chalkiness in rice显示文摘Grain chalkiness,an undesirable trait caused by complex factors,has great negative impacts on the quality and economic value of rice.However,little is known about the regulatory mechanism of grain chalkiness,particularly the effect of endoplasmic reticulum(ER)stress.Here,a genome-wide association study(GWAS)reveals that the transcription factor Osb ZIP60 is a vital regulator of rice grain chalkiness.Genetic analysis demonstrates that knockout of Osb ZIP60 results in extremely high grain chalkiness and aberrant structure of storage substances.Notably,the expression of unfolded protein response(UPR)genes,such as OsbZIP50,Os Bi P1,Os Bi P2 and Os Bi P3,is up-regulated in the endosperm cells of osbzip60,and overexpression of all these UPR genes causes various degrees of chalkiness.Furthermore,Osb ZIP60 is found to activate the expression of key genes related to grain chalkiness,such as GPA3,FSE1,FLO7,Chalk5,Os NF-YB1,and Os PK2,whose expression is significantly suppressed in osbzip60 and overexpression lines of Osb ZIP50,Os Bi P1,Os Bi P2,and Os Bi P3.Our study provides novel insights into the function of Osb ZIP60 and the role of the UPR pathway in the formation of grain chalkiness in rice. | Weiping Yang Pengkun Xu Juncheng Zhang Shuo Zhang Zhenwei Li Ke Yang Xinyuan Chang Yibo Li | 2022 | Journal of Genetics and Genomics2022,49,5: | 4 |
| 2 | Laser spectroscopy imaging technique coupled withnanomaterials for cancer diagnosis: A review显示文摘Laser spectroscopic imaging techniques have received tremendous attention in the-eld of cancer diagnosis due to their high sensitivity,high temporal resolution,and short acquisition time.However,the limited tissue penetration of the laser is still a challenge for the in vivo diagnosis of deep-seated lesions.Nanomaterials have been universally integrated with spectroscopic imaging techniques for deeper cancer diagnosis in vivo.The components,morphology,and sizes of nanomaterials are delicately designed,which could realize cancer diagnosis in vivo or in situ.Considering the enhanced signal emitting from the nanomaterials,we emphasized their combination with spectroscopic imaging techniques for cancer diagnosis,like the surface-enhanced Raman scattering(SERS),photoacoustic,fluorescence,and laser-induced breakdown spectroscopy(LIBS).Applications ofthe above spectroscopic techniques offer new prospectsfor cancer diagnosis. | Zhengying Peng Pengkun Yin Dan Li Youyuan Chen Kaiqiang Shu Qingwen Fan Yixiang Duan Qingyu Lin | 2024 | Journal of Innovative Optical Health Sciences2024,17,1: | 0 |
| 3 | Trends of Underweight Malnutrition Among Chinese Residents Aged 60 Years and Above—China,1992−2015显示文摘Summary What is already known about this topic?The prevalence of underweight malnutrition largely decreased in Chinese adults in recent thirty years while obesity became increasingly concerning.However,underweight malnutrition still affected elderly populations and increased risk of anemia,infection diseases,some non-communicable chronic diseases and disability. | Pengkun Song Qingqing Man Yuqian Li Shanshan Jia Dongmei Yu Zhen Liu Jian Zhang | 2021 | China CDC weekly2021,3,11: | 0 |
| 4 | Assessing the Influence of Aerosol on Radiation and Its Roles in Planetary Boundary Layer Development显示文摘A comprehensive measurement of planetary boundary layer(PBL)meteorology was conducted at 140 and 280 m on a meteorological tower in Beijing,China,to quantify the effect of aerosols on radiation and its role in PBL development.The measured variables included four-component radiation,temperature,sensible heat flux(SH),and turbulent kinetic energy(TKE)at 140 and 280 m,as well as PBL height(PBLH).In this work,a method was developed to quantitatively estimate the effect of aerosols on radiation based on the PBLH and radiation at the two heights(140 and 280 m).The results confirmed that the weakened downward shortwave radiation(DSR)on hazy days could be attributed predominantly to increased aerosols,while for longwave radiation,aerosols only accounted for around onethird of the enhanced downward longwave radiation.The DSR decreased by 55.2 W m^(-2) on hazy days during noontime(1100–1400 local time).The weakened solar radiation decreased SH and TKE by enhancing atmospheric stability,and hence suppressed PBL development.Compared with clean days,the decreasing rates of DSR,SH,TKE,and PBLH were 11.4%,33.6%,73.8%,and 53.4%,respectively.These observations collectively suggest that aerosol radiative forcing on the PBL is exaggerated by a complex chain of interactions among thermodynamic,dynamic,and radiative processes.These findings shed new light on our understanding of the complex relationship between aerosol and the PBL. | Zhigang CHENG Yubing PAN Ju LI Xingcan JIA Xinyu ZHANG Pengkun MA Qianqian WANG Junxia DOU Jingjiang ZHANG Jiannong QUAN | 2021 | Journal of Meteorological Research2021,35,2: | 0 |
| 5 | T-IP: A Self-Trustworthy and Secure Internet Protocol显示文摘IPsec has become an important supplement of IP to provide security protection. However, the heavyweight IPsec has a high transmission overhead and latency, and it cannot provide the address accountability. We propose the self-trustworthy and secure Internet protocol(T-IP) for authenticated and encrypted network layer communications. T-IP has the following advantages:(1) Self-Trustworthy IP address.(2) Low connection latency and transmission overhead.(3) Reserving the important merit of IP to be stateless.(4) Compatible with the existing TCP/IP architecture. We theoretically prove the security of our shared secret key in T-IP and the resistance to the known session key attack of our security-enhanced shared secret key calculation. Moreover, we analyse the possibility of the application of T-IP, including its resilience against the man-in-the-middle attack and Do S attack. The evaluation shows that T-IP has a much lower transmission overhead and connection latency compared with IPsec. | Xiaofeng Wang Huan Zhou Jinshu Su Baosheng Wang Qianqian Xing Pengkun Li | 2018 | China Communications2018,15,2: | 0 |
| 6 | Blockchain Data Analysis from the Perspective of Complex Networks:Overview显示文摘Cryptocurrency based on blockchain technology has gradually become a choice for people to invest in,and several users have participated in the accumulation of massive transaction data.Complete transaction records in blockchains and the openness of data provide researchers with opportunities to mine and analyze data in blockchains.Network modeling and analysis of cryptocurrency transaction records are common methods in blockchain data analysis.The analysis of attribute graphs can provide insights into various economic indicators,illegal activities,and general Internet security,among others.Accordingly,this article aims to summarize and analyze the literature on cryptocurrency transaction data from the perspective of complex networks.To provide systematic guidance for researchers,we put forward a blockchain data analysis framework based on the introduction of the relevant background and reviewed the work from five aspects:blockchain data model,data acquisition on blockchains,existing analysis tools,available insights,and common analysis methods.For each aspect,we introduce the research problems,summarize the methods,and discuss the results and findings.Finally,we present future research points and several open questions in the study of cryptocurrency transaction networks. | Wanshui Song Wenyin Zhang Jiuru Wang Linbo Zhai Pengkun Jiang Shanyun Huang Bei Li | 2023 | Tsinghua Science and Technology2023,28,1: | 0 |
| 7 | Risk field assessment of longwall working face by the double-sided roof cutting along the gob显示文摘In order to study the mechanism of the dual side roof cutting technology on the composite disaster of gas and coal spontaneous combustion in goaf,a model for the evolution of porosity and permeability in the dual side roof cutting working face was constructed.The location of the occurrence of the compound disaster of gas explosion and coal spontaneous combustion under the double-sided roof cutting mode was studied,and the sensitivity of the evolution pattern of the compound disaster area to the amount of air supply and gas gush was summarized.The results indicate that the top cutting pressure relief technology significantly reduces the permeability of porous media,and the sensitivity of the goaf on the intake side to airflow disturbances is significantly reduced.As the volume of air supply increases,the distance between the gas explosion risk area and the coal spontaneous combustion risk area gradually decreases,and the probability of composite disaster areas is 0.The increase of air supply and gas emission makes the gas concentration in the middle and deep goaf increase in an exponential function,and the width of the gas explosion risk area increases gradually.When the outflow reaches 40 m^(3)/min,there is no composite disaster zone,indicating that the rapid increase in outflow inhibits the occurrence of composite disasters. | Dongyin Li Pengkun Chen Jinzhao Liu Shen Wang Huawei Xu | 2023 | Geohazard Mechanics2023,1,4: | 0 |
| 8 | Health Status and Food Intake Frequency of Elderly Residents During COVID-19 Community Closure—Jiangxia District,Wuhan City,China,2020显示文摘What is already known about this topic?Elderly persons are vulnerable to infectious diseases,and nutritional status and health conditions were important to evaluate for disease prevention and ability to recover for the elderly during the coronavirus disease 2019(COVID-19)pandemic.What is added by this report?In our study,a rapid assessment questionnaire was used to investigate the change of household life and dietary intake of the elderly(aged 60 years or more)during community closure.Food consumption frequency of aquatic food products,soybeans,and fresh fruits declined dramatically with reductions of 70.9%,70.9%,and 53.0%,respectively,and 49.6%of the elderly lived with chronic non-communicable diseases but had little knowledge of nutrition and health.What are the implications for public health practice?Community closure measures in Wuhan City have played a key role in cutting off the transmission route of COVID-19 and protecting vulnerable groups.As a high-risk population,the elderly should be advised to maintain and strengthen a balanced diet with proper nutrition through increasing intake of aquatic food products,soybeans,fruits,and vegetables,reducing total caloric intake,and decreasing oil and salt consumption.These measures will be significant for the elderly to reduce the risk of chronic disease complications and COVID-19 infection and to decrease the chance of critical illness. | Pengkun Song Cheng Li Ganyu Feng Jian Zhang Li Li Titi Yang Mingna Dong Ailing Liu Qi Zhang Yujing Liu Jinglei Wang Tanxi Ge Qing Yu Gangqiang Ding | 2020 | China CDC weekly2020,2,27: | 0 |
| 9 | Diet and Nutrition of Healthcare Workers in COVID-19 Epidemic—Hubei,China,2019显示文摘From late January to March,more than 42,000 doctors,nurses,public health workers,and health administrators across China went to Hubei Province to assist in the response to coronavirus disease 2019(COVID-19).There are many studies on nutrition status of affected people amid natural disasters or pandemics(1–3),but the diet and nutrition status of healthcare workers receive little attention.The aim of this article is to provide evidence for addressing this issue by investigating food supply and nutrition status during the COVID-19 response period. | Jian Zhang Shanrong Lai Quanjun Lyu Pianhong Zhang Dagang Yang Juan Kong Yumei Qi Wei Yuan Shan Zeng Pengkun Song Titi Yang Li Li Jinglei Wang Yujing Liu Tanxi Ge Qi Zhang Ganyu Feng Ailing Liu Gangqiang Ding | 2020 | China CDC weekly2020,2,27: | 0 |