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您的检索式：作者名="Pengkai Tang"
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| 1 | Xuebijing injection alleviates liver injury by inhibiting secretory function of Kupffer cells in heat stroke rats显示文摘OBJECTIVE:To evaluate the effects of Xuebijing(XBJ) injection in heat stroke(HS) rats and to investigate the mechanisms underlying these effects.METHODS:Sixty anesthetized rats were randomized into three groups and intravenously injected twice daily for 3 days with 4 mL XBJ(XBJ group) or phosphate buffered saline(HS and Sham groups) per kg body weight.HS was initiated in the HS and XBJ groups by placing rats in a simulated climate chamber(ambient temperature 40 ℃,humidity 60%).Rectal temperature,aterial pressure,and heart rate were monitored and recorded.Time to HS onset and survival were determined,and serum concentrations of tumor necrosis factor(TNF)-α,inRESULTS:Time to HS onset and survival were significantly longer in the XBJ than in the HS group.Moreover,the concentrations of TNF-α,IL-1β,IL-6,ALT and AST were lower and liver injury was milder in the XBJ than in the HS group.Heat-stress induced structural changes in KCs and hepatic cells were more severe in the HS than in the XBJ group and the concentrations of TNF-α,IL-β and IL-6 secreted by KCs were lower in the XBJ than in the HS group.CONCLUSION:XBJ can alleviate HS-induced systemic inflammatory response syndrome and liver injury in rats,and improve outcomes.These protective effects may be due to the ability of XBJ to inhibit cytokine secretion by KCs. | Yi Chen Huasheng Tong Xingqin Zhang Liqun Tang Zhiguo Pan Zhifeng Liu Pengkai Duan Lei Su | 2013 | Journal of Traditional Chinese Medicine2013，33，2： | 14 |
| 2 | Reinforced Lewis covalent bond by twinborn nitride heterostructure for lithium-sulfur batteries显示文摘The practical application of lithium-sulfur(Li-S)batteries,as promising next-generation batteries,is hindered by their shuttle effect and the slow redox kinetics.Herein,a tungsten and molybdenum nitride heterostructure functionalized with hollow metal-organic framework-derived carbon(W_(2)N/Mo_(2)N)was proposed as the sulfur host.The hollow spherical structure provides storage space for sulfur,enhances electrical conductivity,and inhibits volume expansion.The metal atoms in the nitrides bonded with lithium polysulfides(Li PSs)through Lewis covalent bonds,enhancing the high catalytic activity of the nitrides and effectively reducing the energy barrier of Li PSs redox conversion.Moreover,the high intrinsic conductivity of nitrides and the ability of the heterostructure interface to accelerate electron/ion transport improved the Li+transmission.By leveraging the combined properties of strong adsorption and high catalytic activity,the sulfur host effectively inhibited the shuttle effect and accelerated the redox kinetics of Li PSs.High-efficiency Li+transmission,strong adsorption,and the efficient catalytic conversion activities of Li PSs in the heterostructure were experimentally and theoretically verified.The results indicate that the W_(2)N/Mo_(2)N cathode provides stable,and long-term cycling(over 2000 cycles)at 3 C with a low attenuation rate of 0.0196%per cycle.The design strategy of a twinborn nitride heterostructure thus provides a functionalized solution for advanced Li-S batteries. | Yaochen Song Pengkai Tang Yanjie Wang Yi Wang Linnan Bi Qi Liang Liang He Qingyu Xie Yiyong Zhang Peng Dong Yingjie Zhang Yao Yao Jiaxuan Liao Sizhe Wang | 2024 | Journal of Energy Chemistry2024，88，1： | 0 |
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