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159篇 您的检索式:作者名="Pengbo"
    题名 作者 年代 出处 被引量
1Photoactivated CRY1 and phyB Interact Directly with AUX/IAA Proteins to Inhibit Auxin Signaling in Arabidopsis显示文摘光是在 Arabidopsis 通过蓝色和调停 cryptochrome 的 red/far-red 光光敏电阻器和调停 phytochrome 的小径禁止胚轴房间延伸的关键环境暗示。相反,作为枢轴的内长的植物激素,植物生长素通过 AUX/IAA 蛋白质(AUX/IAAs ) 的植物生长素受体 TIR1/AFBs-mediated 降级支持胚轴延伸。然而,位于发信号的光和植物生长素的对抗相互作用下面的分子的机制仍然保持不清楚。这里,我们报导光禁止由 cryptochrome 的蓝、红的轻依赖者的相互作用通过 AUX/IAAs 的稳定发信号的植物生长素 1 (CRY1 ) 并且有 AUX/IAAs 的 phytochrome B 分别地。有 AUX/IAAs 的 CRY1 的蓝被触发光的相互作用与 AUX/IAAs 禁止 TIR1 的协会,导致这些蛋白质的导致植物生长素的降级的压抑。我们的结果显示光敏电阻器下游地直接作为一样与植物生长素受体分享 AUX/IAAs 表明部件。我们建议由光敏电阻器和植物生长素受体的 AUX/IAA 蛋白质稳定性的那条对抗规定允许植物平衡光和植物生长素信号优化他们的生长。Feng Xu Shengbo He Jingyi Zhang Zhilei Mao Wenxiu Wang Ting Li Jie Hua Shasha Du Pengbo Xu Ling Li Hongli Lian Hong-Quan Yang 2018Molecular Plant2018,11,4:24
2TGFβ inhibition enhances the generation of hematopoietic progenitors from human ES cell-derived hemogenic endothelial cells using a stepwise strategy显示文摘Chengyan Wang Xuming Tang Xiaomeng Sun Zhenchuan Miao Yaxin Lv Yanlei Yang Huidan Zhang Pengbo Zhang Yang Liu LiyingDu Yang Gao Ming Yin Mingxiao Ding Hongkui Deng 2012Cell Research2012,22,1:17
3Experimental investigation of railway train-induced vibrations of surrounding ground and a nearby multi-story building显示文摘In this paper, a field experiment was carried out to study train-induced environmental vibrations. During the field experiment, velocity responses were measured at different locations of a six-story masonry structure near the Beijing-Guangzhou Railway and along a small road adjacent to the building. The results show that the velocity response levels of the environmental ground and the building floors increase with train speed, and attenuate with the distance to the railway track. Heavier freight trains induce greater vibrations than lighter passenger trains. In the multi-story building, the lateral velocity levels increase monotonically with floor elevation, while the vertical ones increase with floor elevation in a fluctuating manner. The indoor floor vibrations are much lower than the outdoor ground vibrations. The lateral vibration of the building along the direction of weak structural stiffness is greater than along the direction with stronger stiffness. A larger room produces greater floor vibrations than the staircase at the same elevation, and the vibration at the center of a room is greater than at its corner. The vibrations of the building were compared with the Federal Transportation Railroad Administration (FTA) criteria for acceptable ground-borne vibrations expressed in terms of rms velocity levels in decibels. The results show that the train-induced building vibrations are serious, and some exceed the allowance given in relevant criterion.Xia He Chen Jianguo Wei Pengbo Xia Chaoyi G. De Roeck G. Degrande 2009Earthquake Engineering and Engineering Vibration2009,8,1:13
4Design and Implementation of a 3D Ocean Virtual Reality and Visualization Engine显示文摘In this study,a 3D virtual reality and visualization engine for rendering the ocean,named VV-Ocean,is designed for marine applications.The design goals of VV-Ocean aim at high fidelity simulation of ocean environment,visualization of massive and multidimensional marine data,and imitation of marine lives.VV-Ocean is composed of five modules,i.e.memory management module,resources management module,scene management module,rendering process management module and interaction management module.There are three core functions in VV-Ocean:reconstructing vivid virtual ocean scenes,visualizing real data dynamically in real time,imitating and simulating marine lives intuitively.Based on VV-Ocean,we establish a sea-land integration platform which can reproduce drifting and diffusion processes of oil spilling from sea bottom to surface.Environment factors such as ocean current and wind field have been considered in this simulation.On this platform oil spilling process can be abstracted as movements of abundant oil particles.The result shows that oil particles blend with water well and the platform meets the requirement for real-time and interactive rendering.VV-Ocean can be widely used in ocean applications such as demonstrating marine operations,facilitating maritime communications,developing ocean games,reducing marine hazards,forecasting the weather over oceans,serving marine tourism,and so on.Finally,further technological improvements of VV-Ocean are discussed.CHEN Ge LI Bo TIAN Fenglin JI Pengbo LI Wenqing 2012Journal of Ocean University of China2012,11,4:10
5Photoexcited CRYPTOCHROME 1 Interacts Directly with G-Protein 13 Subunit AGB1 to Regulate the DNA-Binding Activity of HY5 and Photomorphogenesis in Arabidopsis显示文摘Hongli Lian Pengbo Xu Shengbo He Jun Wu Jian Pan Wenxiu Wang Feng Xu Sheng Wang Junsong Pan Jirong Huang Hong-Quan Yang 2018Molecular Plant2018,11,10:10
6Probing the seeded protocol for high-concentration preparation of silver nanowires显示文摘因为它的潜在的应用,高质量的银 nanowires (Ag NW ) 的大量生产具有重要重要性。卤素离子广泛地为 Ag NW 的合成被使用了;然而由于进异构的成核过程的深卓见的缺乏,通常喂数量的踪迹(例如[Cl -]< 0.25 公里) 被使用,它接着降低先锋的集中([Ag +]) 。这里,我们系统地调查了成核和 Ag NW 的生长行为并且断定异构的成核地点的数字由 AgCl 种子的全部的表面区域被决定,它在降水期间显示了在 Ag + 和 Cl - 的集中之间的一种线性关系。基于这机制,我们成功地与在以前报导的策略作为与那相比为一个水的系统更高为一个 polyol 系统和 5 次高 20 倍的 Ag + 集中生产了高质量的 Ag NW。而且由由控制 AgCl 种子的尺寸定制异构的成核地点,最后的 Ag NW 的直径能是甚至在高 Ag + 集中控制的井。基于机械学的理解,这合成策略能被扩大到另外的 AgX 种子(X = Br -, 我 - 并且 42-) 和基本原则能因此被使用帮助另外的产量很高的金属 NW 的合理合成做好悦耳的尺寸。Cheng Wang Baisong Cheng Haichuan Zhang Pengbo Wan Liang Luo Yun Kuang Xiaoming Sun 2016Nano Research2016,9,5:8
7LSECtin on tumor-associated macrophages enhances breast cancer sternness via interaction with its receptor BTN3A3显示文摘Macrophages have bee n suggested to con tribute to con structing a cancer stem cell(CSC)niche.However,whether and how macrophages regulate the activity of CSCs through juxtacrine signaling are poorly understood.Here we report LSECtin,a transmembrane protein highly expressed on tumor-associated macrophages(TAMs),enhances sternness of breast cancer cells(BCCs).We identified BTN3A3,a B7 family member with previously unknown functions as the receptor for LSECtin on BCCs responsible for stemness-promoting effect of LSECtin.In mice bearing human tumor xenografts,either macrophage-specific ablation of LSECtin or silencing of BTN3A3 in BCCs decreased CSC frequency and tumor growth.Admixture of LSECtin-positive macrophages increased the tumorigenic activity of BCCs dependent on BTN3A3.Disruption of the LSECtin-BTN3A3 axis with BTN3A3-Fc or anti-BTN3A3 mAb has a therapeutic effect on breast cancer.These findings define a juxtacrine signaling mechanism by which TAMs promote cancer stemness.Targeting this axis in the CSC niche may provide potential therapies to breast cancer.Di Liu Qian Lu Xing Wang Jun Wang Ning Lu Zefei Jiang Xiaopeng Hao Jianbin Li Jing Liu Pengbo Cao Guilin Peng Yuandong Tao Dianyuan Zhao Fuchu He Li Tang 2019Cell Research2019,29,5:8
8QoS-Aware Dynamic Resource Management in Heterogeneous Mobile Cloud Computing Networks显示文摘In mobile cloud computing(MCC) systems,both the mobile access network and the cloud computing network are heterogeneous,implying the diverse configurations of hardware,software,architecture,resource,etc.In such heterogeneous mobile cloud(HMC) networks,both radio and cloud resources could become the system bottleneck,thus designing the schemes that separately and independently manage the resources may severely hinder the system performance.In this paper,we aim to design the network as the integration of the mobile access part and the cloud computing part,utilizing the inherent heterogeneity to meet the diverse quality of service(QoS)requirements of tenants.Furthermore,we propose a novel cross-network radio and cloud resource management scheme for HMC networks,which is QoS-aware,with the objective of maximizing the tenant revenue while satisfying the QoS requirements.The proposed scheme is formulated as a restless bandits problem,whose 'indexability' feature guarantees the low complexity with scalable and distributed characteristics.Extensive simulation results are presented to demonstrate the significant performance improvement of the proposed scheme compared to the existing ones.SI Pengbo ZHANG Qian F. Richard YU ZHANG Yanhua 2014China Communications2014,11,5:7
9Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis显示文摘CUL4B ubiquitin ligase 基因的变化有原因地被连接到 syndromic X 连接智力迟钝(XLMR ) 。然而,在 neuronal 和发展缺点的 CUL4B 变化的病原的角色没被理解。我们与 Cul4b 的指向的混乱产生了老鼠,并且与显著生长抑制观察了胚胎的致命性并且在胚胎外的纸巾增加了 apoptosis。Cul4b,然而并非它的 paralog Cul4a,在胚胎外的纸巾驿站培植在高水平被表示。在一根胚胎外的房间线的 CUL4B 表示的 Silencing 导致了 CUL4 底层 p21 Cip1/WAF 和 G2/M 房间周期逮捕 Cip1/WAF 。Cul4b 的 Epiblast 特定的删除阻止了胚胎的致命性并且产生了可行 Cul4b 空老鼠。因此,当时在胚胎非必需合适, Cul4b 在胚胎外的纸巾执行一个必要发展角色。我们的学习提供策略产生可行 Cul4b 缺乏的老鼠为潜在的 neuronal 和人的 CUL4B XLMR 病人的行为的缺乏建模。Liren Liu Yan Yin Yuewei Li Lisa Prevedel Elizabeth H Lacy Liang Ma Pengbo Zhou 2012Cell Research2012,22,8:6
10Selective transmission and channel estimation in massive MIMO systems显示文摘Massive MIMO systems have got extraordinary spectral efficiency using a large number of base station antennas,but it is in the challenge of pilot contamination using the aligned pilots.To address this issue,a selective transmission is proposed using time-shifted pilots with cell grouping,where the strong interfering users in downlink transmission cells are temporally stopped during the pilots transmission in uplink cells.Based on the spatial characteristics of physical channel models,the strong interfering users are selected to minimize the inter-cell interference and the cell grouping is designed to have less temporally stopped users within a smaller area.Furthermore,a Kalman estimator is proposed to reduce the unexpected effect of residual interferences in channel estimation,which exploits both the spatial-time correlation of channels and the share of the interference information.The numerical results show that our scheme significantly improves the channel estimation accuracy and the data rates.杨睿哲 Zong Liang Si Pengbo Ma Dawei Zhang Yanhua 2016High Technology Letters2016,22,1:5
11Construction and initial analysis of five Fosmid libraries of mitochondrial genomes of cotton(Gossypium)显示文摘Cotton(Gossypium)is an important crop providing textile fiber and edible oil.To gain the insights into mechanism of the cytoplasmic male sterility(CMS)inheritance,we constructed five fosmid libraries of mitochondrial genomes from mitotype of G.harknessii Brandegee.(one CMS line and its restorer),mitotype of G.hirsutum L.(one CMS line and its maintainer),and G.barbadense L.The numbers of the clones in these libraries ranged from 1152 to 2016 with an average insert size of 36.2 to 38.4 kb,equivalent to 70–119.3 mitogenomes.The libraries were screened with 28 markers derived from the conservative sequences and yielded 22,19,26,21,and 23 positive clones,respectively.These positive clones were used to construct the physical map of G.harknessii Brandegee.CMS line and G.barbadense L.mitogenomes that shared six syntenis regions.A total of 30 genes in nine clusters showed conservative and had high similarity with those in the mitochondrial genomes of cotton,Carica papaya,Cucurbita pepo and Nicotiana tabacum.Further investigation indicated that gene rrn26 had two copies in all five cotton mitogenomes,while genes atp1,rrn5 and rrn18 had two copies only in G.barbadense L.The positive clones and physical map are considered being useful resources in cotton genomics research.LI ShuangShuang LIU GuoZheng CHEN ZhiWen WANG YuMei LI PengBo HUA JinPing 2013Chinese Science Bulletin2013,58,36:5
12Mechanical, tribological and heat resistant properties of fluorinated multi-walled carbon nanotube/bismaleimide/cyanate resin nanocomposites显示文摘Bismaleimide containing cyanate resin(BMI/CE) pre-ploymer was used as resin matrix. Fluorinated multiwalled carbon nanotubes(F-MWCNTs) were used as fillers to prepare F-MWCNT/BMI/CE nanocomposites via a solution intercalation method. The influence of F-MWCNT content on the mechanical, tribological and heat resistant properties of the nanocomposites was investigated. The morphology of the fracture surface and the wear surface of nanocomposites were characterized by scanning electron microscopy.Results show that the addition of F-MWCNTs is beneficial to improving the mechanical and tribological properties of the nanocomposites. It's worth noting that when the content of F-MWNTs was 0.6 wt%, the performances of nanocomposite are optimized(i.e., highest impact strength, lowest frictional coefficient and wear rate). In addition, the nanocomposites exhibit good thermal stability in comparison with BMI/CE.Pengbo Li Tiehu Li Hongxia Yan 2017Journal of Materials Science & Technology2017,33,10:5
13A Total of 2,657 Reported Cases and 14 Deaths Due to Hemorrhagic Fever with Renal Syndrome—Shaanxi Province,China,January 1–December 19,2021显示文摘Hemorrhagic fever with renal syndrome(HFRS)is a group of illnesses that are caused by hantaviruses.Although increased exposure to rodents or their urine and droppings could be a decisive factor of the increasing in incidence,further research is still needed to elucidate the causes of the epidemic(1).Since October 2021,the number of reported cases of HFRS has been increasing rapidly in Shaanxi Province.As of December 19,2021,a total of 2,657 cases were reported with 14 deaths.Jing Wei Xiaoxia Huang Shen Li Shanshan Du Pengbo Yu Jiandong Li 2021China CDC weekly2021,3,53:5
14Phytochrome B and AGB1 Coordinately Regulate Photomorphogenesis by Antagonistically Modulating PIF3 Stability in Arabidopsis显示文摘Phytochrome B (phyB), the primary red light photoreceptor, promotes photomorphogenesis in Arabidopsis by interacting with the basic helix-loop-helix transcriptional factor PIF3 and inducing its phosphorylation and degradation. Heterotrimeric G proteins are known to regulate various developmental processes in plants and animals. In Arabidopsis, the G-protein β subunit AGB1 is known to repress photomorphogenesis. However, whether and how phyB and AGB1 coordinately regulate photomorphogenesis are largely unknown. Here we show that phyB physically interacts with AGB1 in a red light-dependent manner and that AGB1 interacts directly with PIF3. Moreover, we demonstrate that the AGB1-PIF3 interaction inhibits the association of PIF3 with phyB, leading to reduced phosphorylation and degradation of PIF3, whereas the phyB-AGB1 interaction represses the association of PIF3 with AGB1, resulting in enhaneed phosphorylation and degradation of PIF3. Our results suggest that phyB and AGB1 antagonistically regulate PIF3 stability by dynamically interacting with each other and PIF3. This dynamic mechanism may allow plants to balanee phyB and G-protein signaling to optimize photomorphogenesis.Pengbo Xu Hongli Lian Feng Xu Ting Zhang Sheng Wang Wenxiu Wang Shasha Du Jirong Huang Hong-Quan Yang 2019Molecular Plant2019,12,2:5
15Dynamical decoupling of electron spins in phosphorus-doped silicon显示文摘Quantum coherence is an important enabling feature underpinning quantum computation. However, because of couplings with its noisy surrounding environment, qubits suffer from the decoherence effects. The dynamical decoupling (DD) technique uses pulse-induced qubit flips to effectively mitigate couplings between qubits and environment. Optimal DD eliminates dephasing up to a given order with the minimum number of pulses. In this paper, we first introduce our recent work on prolonging electron spin coherence in γ-irradiated malonic acid crystals and analyze different decoherence mechanisms in this solid system. Then we focus on electron spin relaxation properties in another system, phosphorous-doped silicon (Si:P) crystals. These properties have been investigated by pulse electron paramagnetic resonance (EPR). We also investigate the performance of the dynamical decoupling technique on this system. Using 8-pulse periodic DD, the coherence time can be extended to 296 μs compared with 112 μs with one-pulse control.RONG Xing WANG Ya YANG JiaHui ZHU JinXian XU WanJie FENG PengBo WEN XuJie SU JiHu DU JiangFeng 2011Chinese Science Bulletin2011,56,7:4
16Prevalence and clinical significance of pathogenic germline BRCA1/2 mutations in Chinese non-small cell lung cancer patients显示文摘Objective: Germline alterations in the breast cancer susceptibility genes type 1 and 2, BRCA1 and BRCA2, predispose individuals to hereditary cancers, including breast, ovarian, prostate, pancreatic, and stomach cancers.Accumulating evidence suggests inherited genetic susceptibility to lung cancer.The present study aimed to survey the prevalence of pathogenic germline BRCA mutations(gBRCAm) and explore the potential association between gBRCAm and disease onset in Chinese advanced non-small cell lung cancer(NSCLC) patients.Methods: A total of 6,220 NSCLC patients were screened using capture-based ultra-deep targeted sequencing to identify patients harboring germline BRCA1/2 mutations.Results: Out of the 6,220 patients screened, 1.03%(64/6,220) of the patients harbored the pathogenic gB RCAm, with BRCA2 mutations being the most predominant mutations(49/64, 76.5%).Patients who developed NSCLC before 50 years of age were more likely to carry gBRCAm(P = 0.036).Among the patients harboring classic lung cancer driver mutations, those with concurrent gBRCAm were significantly younger than those harboring the wild-type gBRCA(P = 0.029).By contrast, the age of patients with or without concurrent gBRCAm was comparable to those of patients without the driver mutations(P = 0.972).In addition, we identified EGFR-mutant patients with concurrent gBRCAm who showed comparable progression-free survival but significantly longer overall survival(P = 0.002) compared to EGFR-mutant patients with wild-type germline BRCA.Conclusions: Overall, our study is the largest survey of the prevalence of pathogenic gBRCAm in advanced Chinese NSCLC patients.Results suggested a lack of association between germline BRCA status and treatment outcome of EGFR-TKI.In addition,results showed a positive correlation between pathogenic gB RCAm and an early onset of NSCLC.Xingsheng Hu Dongyong Yang Yalun Li Li Li Yan Wang Peng Chen Song Xu Xingxiang Pu Wei Zhu Pengbo Deng Junyi Ye Hanhan Zhang Analyn Lizaso Hao Liu Xinru Mao Hai Huang Qian Chu Chengping Hu 2019Cancer Biology & Medicine2019,16,3:4
17Mild Breakthrough Infection in a Healthcare Professional Working in the Isolation Area of a Hospital Designated for Treating COVID-19 Patients—Shaanxi Province,China,March,2021显示文摘Summary What is already known about this topic?Healthcare workers are at high risk of acquiring COVID-19 from occupational exposure to COVID-19 virus during their daily medical service work.Excellent infection prevention and control measures and adequate personal protective equipment(PPE)are essential to reduce the risk of hospital-acquired COVID-19.Chaofeng Ma Songtao Xu Yecheng Yao Pengbo Yu You Xu Rui Wu Hailong Chen Xiaoping Dong 2021China CDC weekly2021,3,19:4
18Preparation and Characterization of Gd^(3+)-doped Monodisperse TiO_2 Hollow Microsphere显示文摘Gd^(3+)-doped monodisperse TiO_2 hollow microspheres with various molar ratios of Gd^(3+)/TBOT were synthesized via a novel process, which involved the preparation of SiO_2 templates, deposition of Gd^(3+)-doped TiO_2 by sol-gel, SiO_2 coating, heat treatment to induce crystallization of TiO_2, and finally etching away the inner SiO_2 templates and outer SiO_2 layers. The synthesized samples were characterized by transmission electron microscopy(TEM), scanning electron microscopy(SEM), X-ray diffraction(XRD), diffuse reflection spectroscopy(DRS), specific surface area measurement(BET) and X-ray photoelectron spectroscopy(XPS), respectively. The photocatalytic activity of Gd^(3+)-doped samples was evaluated via photocatalytic degradation of Methyl orange under UV irradiation. The results show that the SiO_2 layers prevent aggregation of TiO_2 hollow microspheresand improve the thermal stability of the synthesized samples. Also, the photocatalytic activity of monodisperse TiO_2 hollow microspheres can be enhanced at the optimal molar ration of Gd^(3+)/TBOT of 0.7%.JI Feng SHANG Pengbo ZHENG Yuying 2015Journal of the Chinese Ceramic Society2015,,4:3
19Blockchain and MEC-Assisted Reliable Billing Data Transmission over Electric Vehicular Network:An Actor–Critic RL Approach显示文摘Recently,electric vehicles(EVs)have been widely used under the call of green travel and environmental protection,and diverse requirements for charging are also increasing gradually.In order to ensure the authenticity and privacy of charging information interaction,blockchain technology is proposed and applied in charging station billing systems.However,there are some issues in blockchain itself,including lower computing efficiency of the nodes and higher energy consumption in the consensus process.To handle the above issues,in this paper,combining blockchain and mobile edge computing(MEC),we develop a reliable billing data transmission scheme to improve the computing capacity of nodes and reduce the energy consumption of the consensus process.By jointly optimizing the primary and replica nodes offloading decisions,block size and block interval,the transaction throughput of the blockchain system is maximized,as well as the latency and energy consumption of the system are minimized.Moreover,we formulate the joint optimization problem as a Markov decision process(MDP).To tackle the dynamic and continuity of the system state,the reinforcement learning(RL)is introduced to solve the MDP problem.Finally,simulation results demonstrate that the performance improvement of the proposed scheme through comparison with other existing schemes.Xinyu Ye Meng Li Pengbo Si Ruizhe Yang Enchang Sun Yanhua Zhang 2021China Communications2021,18,8:3
20Three-point bending of honeycomb sandwich beams with facesheet perforations显示文摘A novel square honeycomb-cored sandwich beam with perforated bottom facesheet is investigated under threepoint bending,both analytically and numerically.Perforated square holes in the bottom facesheet are characterized by the area ratio of the hole to intact facesheet(perforation ratio).While for large-scale engineering applications like the decks of cargo vehicles and transportation ships,the perforations are needed to facilitate the fabrication process(e.g.,laser welding)as well as service maintenance,it is demonstrated that these perforations,when properly designed,can also enhance the resistance of the sandwich to bending.For illustration,fair comparisons among competing sandwich designs having different perforation ratios but equal mass is achieved by systematically thickening the core webs.Further,the perforated sandwich beam is designed with a relatively thick facesheet to avoid local indention failure so that it mainly fails in two competing modes:(1)bending failure,i.e.,yielding of beam cross-section and buckling of top facesheet caused by bending moment;(2)shear failure,i.e.,yielding and buckling of core webs due to shear forcing.The sensitivity of the failure loads to the ratio of core height to beam span is also discussed for varying perforation ratios.As the perfo-ration ratio is increased,the load of shear failure increases due to thickening core webs,while that of bending failure decreases due to the weakening bottom facesheet.Design of a sandwich beam with optimal perforation ratio is realized when the two failure loads are equal,leading to significantly enhanced failure load(up to 60%increase)relative to that of a non-perforated sandwich beam with equal mass.Pengbo Su Bin Han Zhongnan Zhao Qiancheng Zhang Tian Jian Lu 2018Acta Mechanica Sinica2018,34,4:3
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