|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effects of nonalcoholic fatty liver disease on the development of metabolic disorders显示文摘 | Fan, JG Li, F Cai, XB Peng, YD Ao, QH Gao, Y | 2007 | 中国生物学文摘2007，21，11： | 51 |
| 2 | Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication显示文摘Hepatitis B virus(HBV)can cause chronic hepatitis B,which may lead to cirrhosis and liver cancer.Type I interferon(IFN)is an approved drug for the treatment of chronic hepatitis B.However,the fundamental mechanisms of antiviral action by type I IFN and the downstream signaling pathway are unclear.TRIM25 is an IFN-stimulated gene(ISG)that has an important role in RIG-I ubiquitination and activation.Whether TRIM25 is induced in liver cells by type I IFN to mediate anti-HBV function remains unclear.Here we report that interleukin-27(IL-27)has a critical role in IFN-induced TRIM25 upregulation.TRIM25 induction requires both STAT1 and STAT3.In TRIM25 knockout HepG2 cells,type I IFN production was consistently attenuated and HBV replication was increased,whereas overexpression of TRIM25 in HepG2 cells resulted in elevated IFN production and reduced HBV replication.More interestingly,we found that TRIM25 expression was downregulated in HBV patients and the addition of serum samples from HBV patients could inhibit TRIM25 expression in HepG2 cells,suggesting that HBV might have involved a mechanism to inhibit antiviral ISG expression and induce IFN resistance.Collectively,our results demonstrate that type I IFN-induced TRIM25 is an important factor in inhibiting HBV replication,and the IFN-IL-27-TRIM25 axis may represent a new target for treating HBV infection. | Guangyun Tan Qingfei Xiao Hongxiao Song Feng Ma Fengchao Xu Di Peng Na Li Xiaosong Wang Junqi Niu Pujun Gao F Xiao-Feng Qin Genhong Cheng | 2018 | Cellular & Molecular Immunology2018，15，3： | 13 |
| 3 | 新型泛过氧化物酶体增殖物激活受体激动剂MBT1805对α-萘异硫氰酸酯诱导的小鼠胆汁淤积症的治疗作用显示文摘【据Frontiers in Pharmacology 2021年10月报道】代谢组学分析揭示了新型泛过氧化物酶体增殖物激活受体激动剂MBT1805对α-萘异硫氰酸酯诱导的小鼠胆汁淤积症的治疗作用(作者Wang C等)胆汁淤积性肝损伤的治疗药物相对缺乏。 | WANG C PENG F ZHONG B 王畅 | 2021 | 临床肝胆病杂志2021，37，12： | 5 |
| 4 | Penile prosthesis implantation in Chinese patients wit severe erectile dysfunction: 10-year experience显示文摘我们回顾地与严重可勃起的机能障碍(SED ) 在中国病人评估了阴茎修复术培植(PPI ) 的临床的结果。从 2000 年 7 月到 2011 年 12 月, 224 个病人(吝啬的年龄:35.9 ± 11.8 年,变化:20-75 年) 在我们的中心根据标准 PPI 过程由富有经验的外科医生与 SED 经历了 PPI。韧性的修复术(AMS 650 ) 在 45 种情况中被植入(20.1 %) ,并且三片的可膨胀的修复术(AMS 700 CXM 或 AMS 700 CXR ) 在 179 种情况中被植入(79.9 %) 。包括手术后的复杂并发症,临床的功效和夫妇满足,外科的结果被评估在上比手术后地使用医药记录抽象的 6 个月, IIEF-5,生活(QoL ) 的质量分数,和病人 / 搭挡的性满足分数由 Bhojwani 等求婚了。为学习合格的 224 个病人, 201 使遭到(89.7 %) 完成的后续。所有能与吝啬的手术后的 IIEF-5 病人执行性交柱子 PPI, QoL 分数是 20.02 ± 2.32 和 5.28 ± 0.76,分别地它显著地与外科手术前的分数相比被改进(6.29 ± 1.5 和 2.13 ± 0.84, P< 0.01 ) 。201 个人,机械失灵发生在四种情况中(2.0 %) 并且三个盒子被重新植入新设备,和二个盒子(1.0 %) 开发了阴茎的温和弯曲。有感染的阴囊的侵蚀与糖尿病 mellitus 发生在一种情况中(0.5 %) 并且植入的 AMS 的要求的完全的移动 700 CXM。令人满意的性交被 178 个人两次至少每月报导(88.6 %) ,并且对 PPI 外科的全面满足被 89.0 % 报导;人和 82.5 %搭挡。在三片的可膨胀的修复术组的耐心的满足比在韧性的修复术组高(P< 0.05 ) 。然而,在 prostheses 的类型之间,满足没在搭挡调查不同。PPI 是一种安全、有效的治疗选择因为有 SED 和富有经验的外科医生的中国病人根据标准 PPI 执行 PPI 过程能减少 PPI 的手术后的复杂并发症并且能改进耐心的满足比率和 QoL。 | Wei-Dong Song Yi-Ming Yuan Wan-Shou Cui Alex K Wu Yi-Chen Zhu Jing Liu Lin Wang Guang-Yi Ba Jing Peng Zhi-Chao Zhang Bing Gao Ying-Lu Guo Tom F Lue Zhong-Cheng Xin | 2013 | Asian Journal of Andrology2013，15，5： | 3 |
| 5 | Low-intensity pulsed ultrasound for regenerating peripheral nerves:potential for penile nerve显示文摘Peripheral nerve damage,such as that found after surgery or trauma,is a substantial clinical challenge.Much research continues in attempts to improve outcomes after peripheral nerve damage and to promote nerve repair after injury.In recent years,low-intensity pulsed ultrasound(LIPUS)has been studied as a potential method of stimulating peripheral nerve regeneration.In this review,the physiology of peripheral nerve regeneration is reviewed,and the experiments employing LIPUS to improve peripheral nerve regeneration are discussed.Application of LIPUS following nerve surgery may promote nerve regeneration and improve functional outcomes through a variety of proposed mechanisms.These include an increase of neurotrophic factors,Schwann cell(SC)activation,cellular signaling activations,and induction of mitosis.We searched PubMed for articles related to these topics in both in vitro and in vivo animal research models.We found numerous studies,suggesting that LIPUS following nerve surgery promotes nerve regeneration and improves functional outcomes.Based on these findings,LIPUS could be a novel and valuable treatment for nerve injury-induced erectile dysfunction. | Dong-Yi Peng Amanda B Reed-Maldonado Gui-Ting Lin Shu-Jie Xia Tom F Lue | 2020 | Asian Journal of Andrology2020，22，4： | 3 |
| 6 | A study of active power filters using quad-series voltage-source PWM converters for harmonic compensation显示文摘 | Peng F Z Akagi H Nabae A | 1990 | IEEE Transactions on Power Electronics1990，5，1： | 2 |
| 7 | Chlorophyll meter estimates leaf area based nitrogen concentration of rice 显示文摘 | Peng S B Laza R C Garcia F V | 1995 | Communication of Soil Science and Plant Analysis1995，26，： | 1 |
| 8 | White spot syndrome baculovirus(WSBV) detected in cultured and captured shrimp, crabs and other arthropods 显示文摘 | Lo C F Ho C H Peng S E | 1996 | Dis Aquat Org1996，27，： | 1 |
| 9 | Integrated Computer Program for Simulation of Meshing and Contact of Gear Drives 显示文摘 | LITVIN F L DONNO M D PENG A | 2000 | Computer Methods in Applied Mechanics and Engineering2000，181，13： | 1 |
| 10 | Performance of a combined system of ponds and constructed wetlands for wnstewater reclamation and reuse显示文摘 | Wang L Peng J F Wang B Z | 2005 | Water Sci Technol2005，51，： | 1 |
| 11 | Generalized instantaneous reactive power theory for three-phase power systems显示文摘 | Peng F Z Lai J S | 1996 | 1EEE Transactions on Instrumentation and Measurement1996，45，1： | 1 |
| 12 | Astrocyte-mediated control of cerebral blood flow 显示文摘 | Takano T Tian G F Peng W | 2006 | Nat Neurosci2006，9，2： | 1 |
| 13 | CFD Simulation of Fine Coal Segregation and Stratification in Jigs 显示文摘 | Xia Y k Peng F F Wolfe E | 2007 | Mineral Process2007，82，3： | 1 |
| 14 | 显示文摘 | Li Y X Hu Y F Peng S Q | 2009 | J Phys Chem C2009，113，： | 1 |
| 15 | Synthesis and characterization of substitutional and interstitial nitrogen-doped titanium dioxides with visible light photocatalytic activity显示文摘 | Peng F Cai L Yu H | 2008 | J Solid State Chem2008，181，4： | 1 |
| 16 | University Students' Internet Use and Its Relationships with Academic Performance, Interpersonal Rela- tionships, Psychosocial Adjustment, and Self-evaluation显示文摘 | Chcng Y F Peng S S | 2008 | CyberPsychology & Behavior2008，，11： | 1 |
| 17 | Molecular biomarker evidence of origins and transport of organic matter in sediments of the Pearl River Estuary and adjacent South China Sea 显示文摘 | HU J F PENG P A CHIVAS A R | 2009 | Applied Geochemistry2009，24，9： | 1 |
| 18 | A new approach to harmonic compensation in power system-A combined system of shunt passive and series active filters 显示文摘 | Peng F Z Akagi H Nabae A | 1990 | IEEE Transactions on Industry Applications1990，26，98： | 1 |
| 19 | Dynamic wetting and stress singularity on the contact line 显示文摘 | Wang X D Peng X F Lee D J | 2003 | Science in China E2003，46，4： | 1 |
| 20 | Sea surface temperature variability in the north side of the South China Sea over the last 55 years revealed by coral δ^18O records显示文摘 | Peng Z C He J F Chen T G | 2003 | Geochimica et Cosmochimica Acta2003，67，18： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员