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33篇 您的检索式：作者名="Pedini"

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	题名	作者	年代	出处	被引量
1	De novo malignancies after liver transplantation: The effect of immunosuppression-personal data and review of literature显示文摘BACKGROUND Immunosuppression has undoubtedly raised the overall positive outcomes in the post-operative management of solid organ transplantation. However, long-term exposure to immunosuppression is associated with critical systemic morbidities. De novo malignancies following orthotopic liver transplants (OLTs) are a serious threat in pediatric and adult transplant individuals. Data from different experiences were reported and compared to assess the connection between immunosuppression and de novo malignancies in liver transplant patients. AIM To study the role of immunosuppression on the incidence of de novo malignancies in liver transplant recipients. METHODS A systematic literature examination about de novo malignancies and immunosuppression weaning in adult and pediatric OLT recipients was described in the present review. Worldwide data were collected from highly qualified institutions performing OLTs. Patient follow-up, immunosuppression discontinuation and incidence of de novo malignancies were reported. Likewise, the review assesses the differences in adult and pediatric recipients by describing the adopted immunosuppression regimens and the different type of diagnosed solid and blood malignancy.RESULTS Emerging evidence suggests that the liver is an immunologically privileged organ able to support immunosuppression discontinuation in carefully selected recipients. Malignancies are often detected in liver transplant patients undergoing daily immunosuppression regimens. Post-transplant lymphoproliferative diseases and skin tumors are the most detected de novo malignancies in the pediatric and adult OLT population, respectively. To date, immunosuppression withdrawal has been achieved in up to 40% and 60% of well-selected adult and pediatric recipients, respectively. In both populations, a clear benefit of immunosuppression weaning protocols on de novo malignancies is difficult to ascertain because data have not been specified in most of the clinical experiences. CONCLUSION The selected populations of tolerant pediatric and adult liver transplant recipients greatly benefit from immunosuppression weaning. There is still no strong clinical evidence on the usefulness of immunosuppression withdrawal in OLT recipients on malignancies. An interesting focus is represented by the complete reconstitution of the immunological pathways that could help in decreasing the incidence of de novo malignancies and may also help in treating liver transplant patients suffering from cancer.	Tommaso Maria Manzia Roberta Angelico Carlo Gazia Ilaria Lenci Martina Milana Oludamilola T Ademoyero Domiziana Pedini Luca Toti Marco Spada Giuseppe Tisone Leonardo Baiocchi	2019	World Journal of Gastroenterology2019，25，35：	3
2	Anatomic M-mode : a new technique for quantitative assessment of left ventrieular size and function显示文摘	Mele D Pedini I Alboni P	1998	Am J Cardiol1998，81，12：	1
3	Carbohydrate histo- chemistry of the alimentary canal of the shidrum, Um- brina cirrosa 显示文摘	Pedini V Scoeco P Radaelli G	2001	Journal of Veterinary Medicine Series C2001，30，6：	1
4	Absence ofcaspase 8 and high expression of PED protect primitive neuralcells from cell death 显示文摘	Ricci-Vitiani L Pedini F Mollinari C	2004	J Exp Med2004，200，10：	1
5	Brackishwater aquaculture in the tropics : The problem of acid sulfate soils 显示文摘	Simpson H J Pedini M	1985	FAO Fisheries Cir- cular ( FAO)1985，，：	1
6	Anatomical M-mode: a new techinique assessment of left ventricular size and function 显示文摘	Mele D Pedini I Alboni P	1998	Am J Cardiol1998，81，12：	1
7	Application of the ICHD-II criteria to the diagnosis of primary chionic headaches via a computerized structured record显示文摘	Pedini M Coppola F	2007	Headache2007，47，1：	1
8	MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis显示文摘	Felli N Pedini F Romania P	2009	Haematologica2009，94，：	1
9	Architecture of sheep haemal nodes显示文摘	Gargiulo A M Ceccarelli P Pedini V	1987	Research in Veterinary Science1987，42，3：	1
10	MicroRNA 223 - dependent expression of LMO2 regulates normal erythropoiesis 显示文摘	FELLI N PEDINI F ROMANIA P	2009	Haematologiea2009，94，4：	1
11	MicroRNA 225-de- pendent expression of LMO2 regulates normal erythro- poiesis 显示文摘	Felli N Pedini F Romania P	2009	Haematologica2009，94，4：	1
12	MicroRNA 223 - de- pendent expt'ession of LMO2 regulates normal erythropoie- sis显示文摘	Felli N Pedini F Romania P	2009	Haematologica2009，94，4：	1
13	MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis显示文摘	Felli N Pedini F Romania P		0，，04：	1
14	Increased death receptor resistance and FLIPshort expression in polycythemia vera erythroid precursor cells显示文摘	Zeuner A Pedini F Signore M	2006	Blood2006，107，9：	1
15	Anatomic M-mode : a new technique for quantitative assessment of left ventficular size and function显示文摘	MELE D PEDINI I ALBONI P	1998	Am J Cardiol1998，81，12：	1
16	Pancreatic autoantibodies in Italian patients with newly diagnosed type 1 diabetes mellitus over the age of 20 years显示文摘	C. Betterle F. Lazzarotto A. Fusari R. Zanchetta S. Benedini B. Pedini A. Moscon F. Presotto	2006	Acta Diabetologica2006，，3：	1
17	Assessment of adrenocortical function and autoantibodies in a baby born to a mother with autoimmune polyglandular syndrome type 2 显示文摘	Betterle C Prac D Pedini B	2004	J Endocrinol Invest2004，27，7：	1
18	Stem cell factor protects erythroid precursor cells from chemotherapeutic agents via up-regulation of BCL-2 family proteins显示文摘	Zeuner A Pedini F Signore M	2003	Blood2003，102，1：	1
19	Clinical and subclinical organ-specific autoimmune manifestations in Type 1 (insulin-dependent) diabetic patients and their first-degree relatives显示文摘	C. Betterle F. Zanette B. Pedini F. Presotto L. B. Rapp C. M. Monciotti F. Rigon	1984	Diabetologia1984，，6：	1
20	Clinical and subclinical organ-specific autoimmune manifestations in type 1 (insulindependent) diabetic patients and their first-degree relatives显示文摘	Betterle C Zanette F Pedini B		0，，：	1

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