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| 1 | Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis显示文摘 | Curtis K. Argo Patrick G. Northup Abdullah M.S. Al-Osaimi Stephen H. Caldwell | 2009 | Journal of Hepatology2009,,2: | 3 |
| 2 | Spontaneous bacterial peritonitis prevalence in pretransplant patients and its effect on survival and graft loss post-transplant显示文摘AIM To investigate the incidence of spontaneous bacterial peritonitis(SBP) in pre-transplant patients and its effect on post transplant mortality and graft failure. METHODS We conducted a retrospective cohort study of patient records from the organ procurement and transplant network data set. Patients were identified by the presence of SBP pre-transplant. Univariate post-transplant survival models were constructed using the Kaplan-Meier technique and multivariate models were constructed using the Cox proportional hazards model. Variables that affected post-transplant graft survival were identified in the SBP population. RESULTS Forty-seven thousand eight hundred and eighty patient records were included in the analysis for both groups, and 1966(4.11%) patients were identified in the data set as having pre-transplant SBP. Patients that had pre-transplant SBP had higher rates of graft loss from recurrent hepatitis C virus(HCV)(3.6% vs 2.0%, P < 0.0001), infections leading to graft loss(1.9% vs 1.3%, P = 0.02), primary non-function(4.3% vs 3.0%, P < 0.0001) and chronic rejection(1.1% vs 0.7%, P = 0.04). Kaplan-Meier survival analysis showed a statistically significant difference in all-cause survival in patients with a history of SBP vs those without(P < 0.0001). Pretransplant history of SBP was independently predictiveof mortality due to recurrent HCV(HR = 1.11, 95%CI: 1.02-1.21, P < 0.017) after liver transplantation.CONCLUSION HCV patients prior to the advent of directing acting anti-viral agents had a higher incidence of pre-transplant SBP than other patients on the liver transplant wait list. SBP history pre-transplant resulted in a higher rate of graft loss due to recurrent HCV infection and chronic rejection. | Neeral L Shah Nicolas M Intagliata Zachary H Henry Curtis K Argo Patrick G Northup | 2016 | World Journal of Hepatology2016,8,36: | 2 |
| 3 | Advanced non-alcoholic steatohepatitis cirrhosis: A high-risk population for pre-liver transplant portal vein thrombosis显示文摘AIM To examine if liver transplant recipients with high-risk non-alcoholic steatohepatitis(NASH) are at increased risk for pre-transplant portal venous thrombosis.METHODS Data on all liver transplants in the United States from February 2002 through September 2014 were analyzed. Recipients were sorted into three distinct groups: High-risk(age > 60, body mass index > 30 kg/m2, hypertension and diabetes), low-risk and non-NASH cirrhosis. Multivariable logistic regression models were constructed.RESULTS Thirty-five thousand and seventy-two candidates underwent liver transplantation and of those organ recipients, 465 were transplanted for high-risk and 2775 for lowrisk NASH. Two thousand six hundred and twentysix(7.5%) recipients had pre-transplant portal vein thrombosis; 66(14.2%) of the high-risk NASH group had portal vein thrombosis vs 328(11.8%) of the lowrisk NASH group. In general, all NASH recipients were less likely to be male or African American and more likely to be obese. In adjusted multivariable regression analyses, high-risk recipients had the greatest risk ofpre-transplant portal vein thrombosis with OR = 2.11(95%CI: 1.60-2.76, P < 0.001) when referenced to the non-NASH group.CONCLUSION Liver transplant candidates with high-risk NASH are at the greatest risk for portal vein thrombosis development prior to transplantation. These candidates may benefit from interventions to decrease their likelihood of clot formation and resultant downstream hepatic decompensating events. Prospective study is needed. | Jonathan G Stine Curtis K Argo Shawn J Pelletier Daniel G Maluf Stephen H Caldwell Patrick G Northup | 2017 | World Journal of Hepatology2017,9,3: | 2 |
| 4 | A structural model for maize zein proteins 显示文摘 | Patrick Argos Karl Pedersen M David Marks | 1982 | The Journal of Biological Chemistry1982,257,17: | 1 |
| 5 | Endoscopic cyanoacrylate versus transjugular intrahepatic portosystemic shunt for gastric variceal bleeding: a single-center U.S. analysis显示文摘 | Nicholas J. Procaccini Abdullah M.S. Al-Osaimi Patrick Northup Curtis Argo Stephen H. Caldwell | 2009 | Gastrointestinal Endoscopy2009,,5: | 1 |
| 6 | Primary structural comparison of RNA-dependent polymerases from plant, animal and bacterial viruses 显示文摘 | Gregory Kamer Patrick Argos | 1984 | Nucleic Acids Research1984,12,18: | 1 |
| 7 | Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis显示文摘 | Curtis K. Argo Patrick G. Northup Abdullah M.S. Al-Osaimi Stephen H. Caldwell | 2009 | Journal of Hepatology2009,,2: | 1 |
| 8 | Similarity in gene organization and homob ogy between proteins of animal picornaviruses and a plant comovirus suggest common ancestry of these vi- rus families显示文摘 | Argos Patrick Kamer Gregory Nicklin Martin J H Wimmer E | 1984 | Nucleic Acids Res1984,12,18: | 1 |
| 9 | Endoscopic cyanoacrylate versus transjugular intrahepatic portosystemic shunt for gastric variceal bleeding: a single-center U.S. analysis显示文摘 | Nicholas J. Procaccini Abdullah M.S. Al-Osaimi Patrick Northup Curtis Argo Stephen H. Caldwell | 2009 | Gastrointestinal Endoscopy2009,,5: | 1 |
| 10 | Endoscopic cyanoacrylate versus transjugular intrahepatic portosystemic shunt for gastric variceal bleeding: a single-center U.S. analysis显示文摘 | Nicholas J. Procaccini Abdullah M.S. Al-Osaimi Patrick Northup Curtis Argo Stephen H. Caldwell | 2009 | Gastrointestinal Endoscopy2009,,5: | 1 |
| 11 | Sa1867 Endoscopically-Delivered Neoadjuvant Photodynamic Therapy and Radiofrequency Ablation in Patients With Unresectable Cholangiocarcinoma Awaiting Liver Transplantation: A Pilot Experience显示文摘 | Dushant S. Uppal Patrick G. Northup Curtis K. Argo Shawn J. Pelletier Daniel G. Maluf Osama E. Rahma Paul W. Read Dawn G. Cox Daniel S. Strand Andrew Y. Wang | 2015 | Gastroenterology2015,,4: | 1 |
| 12 | Increased risk of portal vein thrombosis in patients with cirrhosis due to nonalcoholic steatohepatitis显示文摘 | Jonathan G. Stine Neeral L. Shah Curtis K. Argo Shawn J. Pelletier Stephen H. Caldwell Patrick G. Northup | 2015 | Liver Transpl2015,,8: | 1 |