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| 1 | Effects of exercise and weight loss on depressive symptoms among men and women with hypertension显示文摘 | PATRICK JS JAMES AB MICHAEL AB | 2007 | Journal of Psychosomatic Research2007，63，5： | 1 |
| 2 | Evolution of stimulants to treat ADHD: transdermal methylphenidate 显示文摘 | Patrick KS Straughn AB Perkins JS | 2009 | Hum Psychopharmacol2009，24，： | 1 |
| 3 | DNA binding of purified transcription factor NF-κB显示文摘 | Utrick Z Ralf S Patrick AB | 1991 | Biol CHem1991，266，1： | 1 |
| 4 | NF-κB:ten years after显示文摘 | Patrick AB David Baltimore | | 0，，： | 1 |
| 5 | Pharmacokinetics of methylphenidate after oral administration of two modified-release formulations in healthy adults显示文摘 | MARKOWITZ JS STRAUGHN AB PATRICK KS | 2003 | Clin Pharmacokinet2003，42，4： | 1 |
| 6 | Alterations in skeletal perfusion with simulated mierogravity: a possible mechanism for bone remodeling 显示文摘 | Patrick NC Keith W Susan AB | 2000 | Appl Physiol2000，89，： | 1 |
| 7 | Differential activation of transcription factor NF-kB and AP- 1 in rat liver macrophages 显示文摘 | Thuy-Anh TT Karl D Patrick AB | 1995 | Hepatology1995，22，： | 1 |
| 8 | Uncovering genetic and metabolite markers associated with resistance against anthracnose fruit rot in northern highbush blueberry显示文摘Anthracnose fruit rot(AFR),caused by the fungal pathogen Colletotrichum fioriniae,is among the most destructive and widespread fruit disease of blueberry,impacting both yield and overall fruit quality.Blueberry cultivars have highly variable resistance against AFR.To date,this pathogen is largely controlled by applying various fungicides;thus,a more cost-effective and environmentally conscious solution for AFR is needed.Here we report three quantitative trait loci associated with AFR resistance in northern highbush blueberry(Vaccinium corymbosum).Candidate genes within these genomic regions are associated with the biosynthesis of flavonoids(e.g.anthocyanins)and resistance against pathogens.Furthermore,we examined gene expression changes in fruits following inoculation with Colletotrichum in a resistant cultivar,which revealed an enrichment of significantly differentially expressed genes associated with certain specialized metabolic pathways(e.g.flavonol biosynthesis)and pathogen resistance.Using non-targeted metabolite profiling,we identified a flavonol glycoside with properties consistent with a quercetin rhamnoside as a compound exhibiting significant abundance differences among the most resistant and susceptible individuals from the genetic mapping population.Further analysis revealed that this compound exhibits significant abundance differences among the most resistant and susceptible individuals when analyzed as two groups.However,individuals within each group displayed considerable overlapping variation in this compound,suggesting that its abundance may only be partially associated with resistance against C.fioriniae.These findings should serve as a powerful resource that will enable breeding programs to more easily develop new cultivars with superior resistance to AFR and as the basis of future research studies. | MacKenzie Jacobs Samantha Thompson Adrian E.Platts Melanie J.A.Body Alexys Kelsey Amanda Saad Patrick Abeli Scott J.Teresi Anthony Schilmiller Randolph Beaudry Mitchell J.Feldmann Steven J.Knapp Guo-qing Song Timothy Miles Patrick P.Edger | 2023 | Horticulture Research2023，10，10： | 0 |
| 9 | Lean and interpretable digital twins for building energy monitoring - A case study with smart thermostatic radiator valves and gas absorption heat pumps显示文摘The transition to low carbon energy systems poses challenges in terms of energy efficiency.In building refur-bishment projects,efficient technologies such as smart controls and heat pumps are increasingly being used as a substitute for conventional technologies with the aim of reducing carbon emissions and determining operational energy and cost savings,together with other benefits.Measured building performance,however,often reveals a significant gap between the predicted energy use(design stage)and actual energy use(operation stage).For this reason,lean and interpretable digital twins are needed for building energy monitoring aimed at persistence of savings and continuous performance improvement.In this research,interpretable regression models are built with data at multiple temporal resolutions(monthly,daily and hourly)and seamlessly integrated with the goal of verifying the performance improvements due to Smart thermostatic radiator valves(TRVs)and gas absorption heat pumps(GAHPs)as well as giving insights on the performance of the building as a whole.Further,as part of modelling research,time of week and temperature(TOWT)approach is reformulated and benchmarked against its original implementation.The case study chosen is Hale Court sheltered housing,located in the city of Portsmouth(UK).This building has been used for the field-testing of innovative technologies such as TRVs and GAHPs within the EU Horizon 2020 project THERMOSS.The results obtained are used to illustrate possible extensions of the use of energy signature modelling,highlighting implications for energy management and innovative building technologies development. | Massimiliano Manfren Patrick AB James Victoria Aragon Lamberto Tronchin | 2023 | Energy and AI2023，14，4： | 0 |
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