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| 1 | Antibacterial activity of sequentially extracted organic solvent extracts of fruits,flowers and leaves of Lawsonia inermis L.from Jaffna显示文摘Objective:To reveal the antibacterial activity of sequentially extracted different cold organic solvent extracts of fruits,flowers and leaves of Lawsonia inermis(L against)some pathogenic bacteria.Methods:Powders of fruits,flowers and leaves of L inermis were continuously extracted with dichloromethane(DCM),ethyl acetate and ethanol at ambient temperature.The dried extracts were prepared into different concentrations and tested for antibacterial activity by agar well diffusion method,and also the extracts were tested to detennine the available phytochemicals.Results:Except DCM extract of flower all other test extracts revealed inhibitory effect on all tested bacteria and their inhibitory effect differed significantly(P<0.05).The highest inhibitory effect was showed by ethyl acetate extract of flower against Staphylococcus aureus(S.aureus)and Pseudomonas aeruginosa(P.aeruginosa),and ethyl acetate extract of fruit on Escherichia coli(E.coli)and Bacillus subtilis(6.subtilis).The ethyl acetate and ethanol extracts of flower,fruit and leaf expressed inhibition even at 1 mg/100μl against all test bacteria.Among the tested phytochemicals flavonoids were detected in all test extracts except DCM extract of flower.Conclusions:The study demonstrated that the ethyl acetate and ethanol extracts of fruit and flower of L inermis are potentially better source of antibacterial agents compared to leaf extracts of respective solvents. | E Christy Jeyaseelan S Jenothiny MK Pathmanathan JP Jeyadevan | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，10： | 3 |
| 2 | Repeated daily exposure to 2 ppm nitrogen dioxide upregulates the expression of IL- 5, IL-10, IL-13, and ICAM-1 in the bronchial epithelium of healthy human airways 显示文摘 | Pathmanathan S Krishna MT Blomberg A | 2003 | Oecup Environ Med2003，60，： | 1 |
| 3 | Repeated daily exposure to 2 ppm nitrogen dioxide upregulates the expression of IL-5, IL-10, IL-13, and ICAM-I in the bronchial epithelium of healthy human airways 显示文摘 | Pathmanathan S Krishna MT Blomberg A Helleday R Kelly FJ Sandstr/Sm T Frew AJ | 2003 | Occup Environ Med2003，60，1： | 1 |
| 4 | Repeated daily exposure to 2ppm nitrogen dioxide upregulates the expression of IL-5, IL-10, IL-13 and ICAM-1 in the brochial epithelium of healthy human airways显示文摘 | Pathmanathan S Krishna MT Blomberg A | 2003 | Occup Environ Med2003，60，11： | 1 |
| 5 | IQ motif selectivity in human IQGAP1:binding of myosin essential light chain and S100B显示文摘 | Pathmanathan S Elliott SF Mcswiggen S | 2008 | Mol Cell Biochem2008，318，12： | 1 |
| 6 | Repeated Daily Exposure to 2 ppm Nitrogen Dioxide Upregulates the Expression of IL-5 ,IL-10, IL-13, and ICAM-1 in the Bronchial Epithelium of Healthy Human Airways 显示文摘 | Pathmanathan S Krishna M T Blomberg A | 2003 | Occupational and Environmental Medicine2003，60，11： | 1 |
| 7 | The interaction of IQGAPs with calmodulin- like proteins显示文摘 | Pathmanathan S Hamilton E Ateheson E | 2011 | Bioehem Soc Trans2011，39，： | 1 |
| 8 | The C-terminal domain of FUSCA3 negatively regulates mRNA and pro tein levels, and mediates sensitivity to the hormones ab- scisic acid and gibberellic acid in Arabidopsis 显示文摘 | Lu Q S Paz J D Pathmanathan A | 2010 | The Plant Journal2010，64，： | 1 |
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