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| 1 | Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung 显示文摘 | Serls AE Doherty S Parvatiyar P | 2005 | Development2005，132，1： | 1 |
| 2 | Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung显示文摘 | Serls AE Doherty S Parvatiyar P | | 0，，01： | 1 |
| 3 | Towards a theory of business alliance formation显示文摘 | Sheth J N Parvatiyar A | 1990 | Scandinavian International Business Review1990，1，3： | 1 |
| 4 | The helicase DDX41 recog-nizes the bacterial secondary messengers cyclic di-GMP and cyclicdi-AMP to activate a type I interferon immune response 显示文摘 | Parvatiyar K Zhang Z Teles RM | 2012 | NatImmunol2012，13，12： | 1 |
| 5 | The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type Ⅰ interferon immune response显示文摘 | Parvatiyar K Zhang Z Teles RM | 2012 | Nat Immunol2012，13，12： | 1 |
| 6 | Customer Relationship Management: Emerging Practice, Process, and Discipline 显示文摘 | Parvatiyar Atul Jagdish N Seheth | 2001 | Journal of Economic and Social Research2001，3，2： | 1 |
| 7 | Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung显示文摘 | Serls AE Doherty S Parvatiyar P | 2004 | Development2004，132，1： | 1 |
| 8 | The evolution of relationship marketing显示文摘 | Sheth J N and Parvatiyar A | 1995 | International Business Review1995，4，4： | 1 |
| 9 | Customer relationship management:Emerging practice, process, and discipline显示文摘 | Parvatiyar A Sheth J. N | | 0，，： | 1 |
| 10 | The ubiquitin-editing enzyme A20 requires RNFll to downregulate NF-kappaB signalling显示文摘 | Shembade N Parvatiyar K Harhaj N S | 2009 | EMBO J2009，28，5： | 1 |
| 11 | Cardiac troponin mutations and restrictive cardiomyopath显示文摘 | Parvatiyar MS Pinto JR | 2010 | J Biomed Biotechnol2010，，： | 1 |
| 12 | 显示文摘 | Govind R Bishop D F | 1996 | Biotechnol Bioeng1996，50，1： | 1 |
| 13 | 显示文摘 | Govind R Bishop D F | 1996 | J Membr Sci1996，119，1： | 1 |
| 14 | Regulation of inflammatory andantiviral signaling by A20显示文摘 | Parvatiyar K Harhaj EW | 2011 | Microbes Infect2011，13，3： | 1 |
| 15 | Suppressing fatty acid synthase by type Ⅰ interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2显示文摘SARS-CoV-2 is an emerging viral pathogen and a major global public health challenge since December of 2019, with limited effective treatments throughout the pandemic.As part of the innate immune response to viral infection, type Ⅰ interferons(IFN-Ⅰ) trigger a signaling cascade that culminates in the activation of hundreds of genes, known as interferon stimulated genes(ISGs), that collectively foster an antiviral state.We report here the identification of a group of type Ⅰ interferon suppressed genes,including fatty acid synthase(FASN), which are involved in lipid metabolism.Overexpression of FASN or the addition of its downstream product, palmitate, increased viral infection while knockout or knockdown of FASN reduced infection.More importantly, pharmacological inhibitors of FASN effectively blocked infections with a broad range of viruses, including SARS-CoV-2 and its variants of concern.Thus, our studies not only suggest that downregulation of metabolic genes may present an antiviral strategy by type Ⅰ interferon, but they also introduce the potential for FASN inhibitors to have a therapeutic application in combating emerging infectious diseases such as COVID-19. | Saba R.Aliyari Amir Ali Ghaffari Olivier Pernet Kislay Parvatiyar Yao Wang Hoda Gerami Ann-Jay Tong Laurent Vergnes Armin Takallou Adel Zhang Xiaochao Wei Linda D.Chilin Yuntao Wu Clay F.Semenkovich Karen Reue Stephen T.Smale Benhur Lee Genhong Cheng | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 1 |
| 16 | Global analysis of cellular factors and responses involved in Pseudomonas aeruginosa resistance to arsenite 显示文摘 | PARVATIYAR K AESABBAGH E M OCHSNER U A MICHELLE A | 2005 | Journal of Bacteriology2005，187，： | 1 |
| 17 | Structural analysis of the STING adaptor protein reveals a hydrophobic dimer in- terface and mode of cyclic di-GMP binding显示文摘 | Ouyang S Song X Wang Y Ru H Shaw N Jiang Y Niu F Zhu Y Qiu W Parvatiyar K Li Y Zhang R Cheng G Liu Z J | 2012 | Immu nity2012，36，： | 1 |
| 18 | Customer relationship management:emerging practice,process,and discipline显示文摘 | Atul Parvatiyar Seheth Jagdish N | 2001 | Journal of Economic and Social Research2001，3，2： | 1 |
| 19 | Paradigm Shift inlnterfirm Marketing Relationships显示文摘 | Parvatiyar A Sheth J N | 2004 | Research in Marketing2004，，13： | 1 |
| 20 | TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases显示文摘 | Parvatiyar K Barber GN Harhaj EW | | 0，，03： | 1 |
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