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| 1 | Development of Optimized Phenomic Predictors for Efficient Plant Breeding Decisions Using Phenomic-Assisted Selection in Soybean显示文摘The rate of advancement made in phenomic-assisted breeding methodologies has lagged those of genomic-assisted techniques,which is now a critical component of mainstream cultivar development pipelines.However,advancements made in phenotyping technologies have empowered plant scientists with affordable high-dimensional datasets to optimize the operational efficiencies of breeding programs.Phenomic and seed yield data was collected across six environments for a panel of 292 soybean accessions with varying genetic improvements.Random forest,a machine learning(ML)algorithm,was used to map complex relationships between phenomic traits and seed yield and prediction performance assessed using two cross-validation(CV)scenarios consistent with breeding challenges.To develop a prescriptive sensor package for future high-throughput phenotyping deployment to meet breeding objectives,feature importance in tandem with a genetic algorithm(GA)technique allowed selection of a subset of phenotypic traits,specifically optimal wavebands.The results illuminated the capability of fusingML and optimization techniques to identify a suite of in-season phenomic traits that will allow breeding programs to decrease the dependence on resource-intensive end-season phenotyping(e.g.,seed yield harvest).While we illustrate with soybean,this study establishes a template for deploying multitrait phenomic prediction that is easily amendable to any crop species and any breeding objective。 | Kyle Parmley Koushik Nagasubramanian Soumik Sarkar Baskar Ganapathysubramanian Asheesh K.Singh | 2019 | Plant Phenomics2019，1，1： | 5 |
| 2 | 充血性心力衰竭的病理生理和治疗现况显示文摘充血性心力衰竭(心衰)是临床常见的综合征,代偿过度促成恶性循环。正性肌力药物、利尿剂和血管扩张剂均可作为第一线治疗药物,合并用药具协同作用,血管扩张剂已被证实能延长患者生存期,应作为治疗心衰的常规药物,抗心律失常治疗在心衰治疗中的意义尚不肯定。预防为主将更利于降低心衰的致残率和病死率。 | Parmley WW 施海明 | 1989 | 国际心血管病杂志1989，32，5： | 2 |
| 3 | Pathophysiology current therapy of congestive heart failure 显示文摘 | Parmley WW | 1989 | J Am Coll Cardiol1989，13，4： | 1 |
| 4 | Optimization of the indenone ring of indenoisoquinoline topoiso- merase I inhibitors 显示文摘 | Morrell A Placzek M Parmley S | 2007 | J Med Chem2007，50，18： | 1 |
| 5 | Induction of matric metalloprotease-7 is common in mucinous ovarian tumors including early stage disease显示文摘 | K Shigemasa H Tanimoto K Sakata N Nagai TH Parmley K Ohama TJ O’Brien | 2000 | Medical Oncology2000，，1： | 1 |
| 6 | Assessment of passive elastic stiftness fi)r isolated heart muscle and the intact heat1 显示文摘 | Mitsky 1 Parmley WW | 1973 | Cite Res1973，33，2： | 1 |
| 7 | Optimum treatment of stable angina pectoris显示文摘 | Parmley W W | 1998 | Cardiovasc Drugs Ther1998，12，： | 1 |
| 8 | Analysis of Anterior and Posterior Corneal Curvature Changes Using Orbscan Technology in Radial Keratotomy Eyes Exposed to Hypoxia显示文摘 | McMann M A Parmley V C Brady S M | 2002 | Journal of Cataract Refractive Surgery2002，28，2： | 1 |
| 9 | Nitrated in- denoisoquinolines as topoisomerase I inhibitors: a sys- tematic study and optimization显示文摘 | Morrell A Placzek M Parmley S | 2007 | J Med Chem2007，50，18： | 1 |
| 10 | The histopathology of tubal pregnancy显示文摘 | Parmley T H | 1987 | Clin Obstet Gynecol1987，30，1： | 1 |
| 11 | Hearing silence:nonneutral evolution at synonymous sites in mammals显示文摘 | Chamary J V Parmley J L Hurst L D | 2006 | Nature Reviews Genetics2006，7，： | 1 |
| 12 | Laparoscopic exploration for the clinically undetected hernia in infancy and childhood显示文摘 | Geisler DP Jegathesan S Parmley MC | 2001 | A J S2001，182，： | 1 |
| 13 | Immunohistochemical and ultrastr-uctural studies on neuroerdocrine skin carcinoma(Merkelcell carcinoma)显示文摘 | Parmley T | 1988 | J Clin Electron Microscopy1988，21，： | 1 |
| 14 | Assessment of passive elastic stiffness for isolated heart muscle and the intact heart显示文摘 | Mirsky I Parmley WW | 1973 | Circulation Research1973，33，2： | 1 |
| 15 | Succession patterns of zooplankton in fertilized culture ponds without fish显示文摘 | Geiger J G | 1985 | Progr Fish-Cultur1985，47，： | 1 |
| 16 | The expression of lactate dehydrogenase is important for the cell cycle of Toxoplosma gondii 显示文摘 | Anouti FA Tomavo S Parmley S | 2004 | J Biol Chem2004，279，52： | 1 |
| 17 | Regulated secretion of multi-laraeilar vesicles leads to formation of a tubulo-vesicular network in host-cell vacuoles occupied by Toxoplasma gondii显示文摘 | Sibley LD Niesman IR Parmley SF | 1995 | J Cell Sci1995，108，4： | 1 |
| 18 | Laparoscopic exp loration for the clinically undetected hernia in infancy and childhood显示文摘 | Geisler D P Jegathesan S Parmley M C | 2001 | Am J Surg2001，182，6： | 1 |
| 19 | Visual field defect associated with laser in situ keratomileusis显示文摘 | Bushhy DM Parmley VC Paglen P | 2000 | Am J Ophthalmol2000，129，5： | 1 |
| 20 | Molecular charwcterization of a 65-kilodalton Toxoplasma gondii antigen expressed abundantly in the matrix of tissue cysts显示文摘 | Parmley SF Yang S Harth G | 1994 | Mol Biochem Parasitol1994，66，2： | 1 |
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