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| 1 | Direct oral anticoagulant administration in cirrhotic patients with portal vein thrombosis:What is the evidence?显示文摘In recent years,the traditional concept that cirrhosis-related coagulopathy is an acquired bleeding disorder has evolved.Currently,it is known that in cirrhotic patients,the hemostatic system is rebalanced,which involves coagulation factors,fibrinolysis and platelets.These alterations disrupt homeostasis,skewing it toward a procoagulant state,which can lead to thromboembolic manifestations,especially when hemodynamic and endothelial factors co-occur,such as in the portal vein system in cirrhosis.Portal vein thrombosis is a common complication of advanced liver cirrhosis that negatively affects the course of liver disease,prognosis of cirrhotic patients and success of liver transplantation.It is still debated whether portal vein thrombosis is the cause or the consequence of worsening liver function.Anticoagulant therapy is the mainstay treatment for acute symptomatic portal vein thrombosis.In chronic portal vein thrombosis,the role of anticoagulant therapy is still unclear.Traditional anticoagulants,vitamin K antagonists and low-molecular-weight heparin are standard-of-care treatments for portal vein thrombosis.In the last ten years,direct oral anticoagulants have been approved for the prophylaxis and treatment of many thromboembolicrelated diseases,but evidence on their use in cirrhotic patients is very limited.The aim of this review was to summarize the evidence about the safety and effectiveness of direct oral anticoagulants for treating portal vein thrombosis in cirrhotic patients. | Marco Biolato Mattia Paratore Luca Di Gialleonardo Giuseppe Marrone Antonio Grieco | 2022 | World Journal of Hepatology2022，14，4： | 2 |
| 2 | A natural antisense transcript against Rad1 8,specifically expressed in neurons and upregulated during beta-amyloid-induced apoptosis显示文摘 | Parenti R Paratore S Torrisi A | | 0，，09： | 1 |
| 3 | Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin显示文摘 | WONG C E PARATORE C DOURS-ZIMMERMANN M T | 2006 | J Cell Biol2006，175，6： | 1 |
| 4 | CXCR4 and CXCL12 immunoreactivities differentiate primary non-small-cell lung cancer with or without brain metastases显示文摘 | Paratore S Banna GL D'Arrigo M | 2012 | Cancer Biomark2012，10，2： | 1 |
| 5 | CXCR4 and CXCL12 immunoreactivities differentiate primary non-small-cell lung cancer with or without brain metastases显示文摘 | Paratore S Banna GL D’Arrigo M | 2011 | Cancer Biomark2011，10，2： | 1 |
| 6 | CXCR4 is a prognostic marker in acute myelogenous leukemia显示文摘 | Paratore S Banna GL D’Arrigo M | 2007 | Blood2007，109，2： | 1 |
| 7 | Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signaling显示文摘 | Paratore C Goerich DE Suter U | | 0，，20： | 1 |
| 8 | Survivin expression in tuberous sclerosis complex cells显示文摘 | Carelli S Lesma E Paratore S | 2007 | Mol Med2007，13，34： | 1 |
| 9 | Family literacy: Perspective and practices显示文摘 | Morrow L M Paratore J P | | TheReading Teacher0，47，3： | 1 |
| 10 | Neural crest- derived cells with stem cell features can be traced back to multiple lineages in the adult skin显示文摘 | Wong CE Paratore C Dours-Zimmermann MT | 2006 | J Cell Biol2006，175，6： | 1 |
| 11 | Long - term therapy with temozolomide is a feasible option for newly diagnosed glioblastoma:a single - institution experience with as many as 101 temozolomide cy- cles显示文摘 | Barbagallo G M Paratore S Caltabiano R | 2014 | Neurosurg Focus2014，37，6： | 1 |
| 12 | CXCR4 and CXCL12 immunoreactivities differentiate primary non-small-cell lung cancer with or without brain metastases显示文摘 | Paratore S Banna GL D'Arrigo M | 2011 | Cancer Biomark2011，10，2： | 1 |
| 13 | Long - term therapy with temozolomide is a feasible option for new-ly diagnosed glioblastoma: a single - institution experience with as many as 101 temozolomide cycles 显示文摘 | BARBAGALLO G M PARATORE S CALTABIANO R | 2014 | Neurosurg Focus2014，37，6： | 1 |
| 14 | A natural antisense transcript against Rad18,specifically expressed in neurons and up-regulated during beta-amyloid-induced apoptosis显示文摘 | Parenti R Paratore S Torrisi A | 2007 | Eur JNeurosci2007，26，9： | 1 |
| 15 | Dynamic contrast enhanced ultrasound in gastrointestinal diseases:A current trend or an indispensable tool?显示文摘Contrast enhanced ultrasound(CEUS)has been widely implemented in clinical practice because of the enormous quantity of information it provides,along with its low cost,reproducibility,minimal invasiveness,and safety of the secondgeneration ultrasound contrast agents.To overcome the limitation of CEUS given by the subjective evaluation of the contrast enhancement behaviour,quantitative analysis of contrast kinetics with generation of time-intensity curves has been introduced in recent years.The quantification of perfusion parameters[named as dynamic-CEUS(D-CEUS)]has several applications in gastrointestinal neoplastic and inflammatory disorders.However,the limited availability of large studies and the heterogeneity of the technologies employed have precluded the standardisation of D-CEUS,which potentially represents a valuable tool for clinical practice in management of gastrointestinal diseases.In this article,we reviewed the evidence exploring the application of D-CEUS in gastrointestinal diseases,with a special focus on liver,pancreas,and inflammatory bowel diseases. | Mattia Paratore Matteo Garcovich Maria Elena Ainora Laura Riccardi Antonio Gasbarrini Maria Assunta Zocco | 2023 | World Journal of Gastroenterology2023，29，25： | 0 |
| 16 | Dynamic control of high-voltage actuator arrays by light-pattern projection on photoconductive switches显示文摘The ability to control high-voltage actuator arrays relies, to date, on expensive microelectronic processes or on individual wiring of each actuator to a single off-chip high-voltage switch. Here we present an alternative approach that uses on-chip photoconductive switches together with a light projection system to individually address high-voltage actuators. Each actuator is connected to one or more switches that are nominally OFF unless turned ON using direct light illumination. We selected hydrogenated amorphous silicon (a-Si:H) as our photoconductive material, and we provide a complete characterization of its light to dark conductance, breakdown field, and spectral response. The resulting switches are very robust, and we provide full details of their fabrication processes. We demonstrate that the switches can be integrated into different architectures to support both AC and DC-driven actuators and provide engineering guidelines for their functional design. To demonstrate the versatility of our approach, we demonstrate the use of the photoconductive switches in two distinctly different applications—control of µm-sized gate electrodes for patterning flow fields in a microfluidic chamber and control of cm-sized electrostatic actuators for creating mechanical deformations for haptic displays. | Vesna Bacheva Amir Firouzeh Edouard Leroy Aiste Balciunaite Diana Davila Israel Gabay Federico Paratore Moran Bercovici Herbert Shea Govind Kaigala | 2023 | Microsystems & Nanoengineering2023，9，3： | 0 |
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