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| 1 | CD36 expression and lipid metabolism following an oral glucose challenge in South Asians显示文摘AIM:To investigate lipid metabolism and the relationship with monocyte expression of the fatty acid translocase CD36 in South Asians.METHODS:An observational study of South Asians whom as an ethnic group have-a higher risk of developing diabetes.The susceptibility to diabetes is coupled with an earlier and more rapid progression of micro-,and macro-vascular complications.Twentynine healthy South Asian participants [mean age 34.6(8.9) years,76.2% male,mean body-mass index 25.0(5.2) kg/m2] were recruited from an urban residential area of central Birmingham(United Kingdom).The main outcomes measured were post prandial(30 min) and post absorptive(120 min) changes from fasting(0 min) in circulating lipoproteins,lipds and hormones,andmonocyte expression of CD36 post injection of a 75 g oral glucose challenge.The inducements of variations of monocyte CD36 expression were analysed.RESULTS:Our results showed evident changes in monocyte CD36 expression following the glucose challenge(P < 0.001).Non-esterified fatty acids(NEFA) levels decreased progressively during the challenge(P < 0.001),in contrast to increased cholesterol(but not triglyceride) concentrations within very low density lipoprotein(VLDL) and low density lipoprotein subfractions(P < 0.01).Levels of,glucose,serum triglycerides and high density lipoprotein cholesterol remained largely unchanged.Variations of monocyte CD36 were negatively(r =-0.47,P = 0.04) associated to fat from the diet and positively to carbohydrate from the diet(r = 0.65,P < 0.001).CONCLUSION:These data suggest that the initiation of VLDL genesis follows the consumption of glucose within this population,inferring that the sequestration of NEFA from these particles happens due to the increased availability of CD36 receptors.While these are preliminary results,it would appear that lifestyle exposures have a role in moderating the expression of CD36. | Jeetesh V Patel Amitava Banerjee Silvia Montoro-Garcia Eduard Shantsila Mushfique Alam Paul Flinders Kathleen AL Houlton Elizabeth A Hughes Gregory YH Lip Paramjit S Gill | 2015 | World Journal of Diabetes2015，6，7： | 1 |
| 2 | Estimates of Precision a Standard Additions Analysis显示文摘 | Graham R Bruce Paramjit Gill | 1999 | Journal of Chemical Education1999，76，6： | 1 |
| 3 | “激励以患者为中心的医疗照护”面临的挑战显示文摘Rachel Foskett-Tharby及同事描述了英国的最新经验,反思如何更有效地收集和使用患者报告信息。在过去几十年里,患者体验和以患者为中心的医疗照护正逐渐成为一种道德规范。尽管其定义尚存争议,但是以患者为中心的医疗照护包含了患者体验的各个方面,如沟通、共享医疗决策,以及路径服务的设计、连接和实施,如整合医疗。不仅如此,患者体验也被视为医疗质量不可分割的一部分,以致国际上呼吁进一步调整考核和激励结构,以更多地关注患者报告的信息。现有的按绩效付费制度。 | Rachel Foskett-Tharby Nick Hex Antony Chuter Paramjit Gill 朱一丹 | 2018 | 中国医院院长2018，14，10： | 1 |
| 4 | Effects of various media and supplements on laccase production by some white rot fungi显示文摘 | Daljit Singh Arora Paramjit Kaur Gill | 2001 | Bioresource Technology2001，77，： | 1 |
| 5 | Laccase production by some white rot fungi under different nutritional conditions显示文摘 | Daljit Singh Arora Paramjit Kaur Gill | 2000 | Bioresource Technology2000，73，： | 1 |
| 6 | Presence and severity of non-alcoholic fatty liver disease in a large prospective primary care cohort显示文摘 | Matthew J. Armstrong Diarmaid D. Houlihan Louise Bentham Jean C. Shaw Robert Cramb Simon Olliff Paramjit S. Gill James M. Neuberger Richard J. Lilford Philip N. Newsome | 2011 | Journal of Hepatology2011，，1： | 1 |
| 7 | Epidemics and primary care in the UK显示文摘IntroduCtIon The emergence of the novel coronavirus disease(COVID-19)in China has resulted in catastrophic events that echo worldwide.Primary care physicians are carrying some of the burden of managing the epidemic alongside secondary care,which is strug-gling to maintain a concerted effort in the face of the mounting pressure of cases.Epidemics affect communities not only biologically but also psychosocially.General practitioners(GPs)in the UK are well posi-tioned to deliver care via a‘whole-person,holistic approach’as they are the first point of contact and provide continuity of care within communities.By reviewing historical epidemics in different countries,we may be able to address the current issues in worldwide by providing pragmatic solutions.In the UK,the successful response to the influenza and severe acute respiratory syndrome(SARS)epidemics was a result of effective collaboration between different organisations. | Mishkat Shehata Shuxia Zhao Paramjit Gill | 2020 | Family Medicine and Community Health2020，8，2： | 0 |
| 8 | “激励以患者为中心的医疗照护”面临的挑战显示文摘Rachel Foskett—Tharby及同事描述了英国的最新经验,反思如何更有效地收集和使用患者报告信息。 | Rachel Foskett-Tharby Nick Hex Paramjit Gill 朱一丹 武阳丰 | 2018 | 英国医学杂志中文版2018，21，2： | 0 |
| 9 | Multimorbidity and oral health:need for new models of care显示文摘Multimorbidity is defined as patients living with two or more chronic health conditions.The prevalence of multimorbidity is increasing,driven by the ageing population,and represents a major challenge to all healthcare systems because these patients are heavy users of services.The link with oral health is growing although there is need for further robust evidence.There is also need for new models of care to address oral health in patients with multimorbidity. | Balraj Gill Andrew Harris Christopher Tredwin Paramjit Gill | 2020 | Family Medicine and Community Health2020，8，4： | 0 |
| 10 | Methodological challenges of cross-language qualitative research with South Asian communities living in the UK显示文摘Objective:We investigate(1)the influence of ethnic,gender,and age concordance with inter-viewers and(2)how expression of qualitative data varies between interviews delivered in English and community languages(Punjabi/Urdu)with monolingual and bilingual participants across three generations of the Indian Sikh and Pakistani Muslim communities living in the UK.Methods:We analyzed and interpreted semi-structured interview transcripts that were designed to collect data about lifestyles,disease management,community practices/beliefs,and social net-works.First,qualitative content analysis was applied to transcripts.Second,a framework was ap-plied as a guide to identify cross-language illustrations where responses varied in length,expression and depth.Results:Participant responses differed by language and topic.First-generation migrants when discussing religion,culture,or family practice were far likelier to use group or community narra-tives and give a longer response,indicating familiarity with or importance of such issues.Ethnic and gender concordance generated greater rapport between researchers and participants centered on community values and practices.Further,open-ended questions that were less direct were better suited for first-generation migrants.Conclusion:Community-based researchers need more time to complete interviews in second languages,need to acknowledge that narratives can be contextualized in both personal and com-munity views,and reframe questions that may lead to greater expression.Furthermore,we detail a number of recommendations with regard to validating the translation of interviews from commu-nity languages to English as well as measures for testing language proficiency. | Manbinder S.Sidhu Farina Kokab Kate Jolly Tom Marshall Nicola K.Gale Paramjit Gill | 2016 | Family Medicine and Community Health2016，4，2： | 0 |
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