|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effects of disinhibition on spatiotemporal pattern of neuronal first recruitment in neuronal networks显示文摘The propagation of neuronal activities is a key feature to understanding information processing in networks. The analysis based on first-spikes of bursts in turn plays an important role in the research of neuronal activity propagation. Our focus here is to investigate how spatiotemporal patterns of neuronal first-spikes are affected by disinhibition. Multi-electrode arrays were used to record stimulation-evoked bursts of multiple neurons in randomly cultured neuronal networks. Both the precise timing of and the rank relationships between first-spikes were analyzed. Compared with evoked bursts in the network's native state, the precise first-spike latencies in its dis-inhibited state are more consistent and the propagation of its bursting activities is much faster. Additional points of interest are that disinhibited neuronal networks can be evoked to generate stable and distinguishable neuronal first recruitment spatiotemporal patterns specific to the stimulation site, and that the disinhibition may cause the original spatiotemporal patterns to change in a heterogeneous manner with regards to different propagation pathways. | Liangbin Pana,b,c,1, Xindong Songa,b,c,1, Guangxin Xiang a,b,c, Jing Zhua,b,c, Jing Cheng a,b,c,d,a Medical Systems Biology Research Center, Tsinghua University School of Medicine, Beijing 100084, China b Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China c National Engineering Research Center for Beijing Biochip Technology, 18 Life Science Parkway, Beijing 102206, China d State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing 100084, China | 2009 | Progress in Natural Science:Materials International2009，19，5： | 6 |
| 2 | Update on the association of hepatitis B with intrahepatic cholangiocarcinoma:Is there new evidence?显示文摘Intrahepatic cholangiocarcinoma(iCCA)is a subgroup of cholangiocarcinoma that accounts for about 10%-20%of the total cases.Infection with hepatitis B virus(HBV)is one of the most important predisposing factors leading to the formation of iCCA.It has been recently estimated based on abundant epidemiological data that the association between HBV infection and iCCA is strong with an odds ratio of about 4.5.The HBV-associated mechanisms that lead to iCCA are under intense investigation.The diagnosis of iCCA in the context of chronic liver disease is challenging and often requires histological confirmation to distinguish from hepatocellular carcinoma.It is currently unclear whether antiviral treatment for HBV can decrease the incidence of iCCA.In terms of management,surgical resection remains the mainstay of treatment.There is a need for effective treatment modalities beyond resection in both first-and second-line treatment.In this review,we summarize the epidemiological evidence that links the two entities,discuss the pathogenesis of HBV-associated iCCA,and present the available data on the diagnosis and management of this cancer. | Nikolaos Fragkou Lazaros Sideras Panteleimon Panas Christos Emmanouilides Emmanouil Sinakos | 2021 | World Journal of Gastroenterology2021，27，27： | 2 |
| 3 | 阅读困难可否补救? 两种理论驱动干预方案的比较(英文)显示文摘本研究是一个进行中的纵向实验的一部分,该实验旨在比较一个认知干预方案(PREP:PASS阅读促进方案)和一个主要关注语音、命名速度和意义成分的神经心理方案(DEST-RT:DEST补救工具)在阅读困难补救中的效能。从320位儿童构成的初始样本中,选择4组儿童,并一年级接受四周干预后,对他们在许多认知、语言、阅读和正字法测量上的表现进行比较:两个实验组共28名伴有阅读困难的儿童(每组n=14),平均年龄6岁6个月,分配到PREP和DEST-RT补救方案中,两组儿童基于年龄、性别、父母教育水平、非言语和言语能力进行匹配,同时也考虑他们的认知和语言表现剖面;一个阅读水平匹配组(RA-C,n=19),也存在阅读困难,不接受任何处理;一个实足年龄匹配组(CA-C,n=30)。结果表明,所有四组儿童在所有认知、语言、阅读和正字法测量上均随时间而改善;与CA-C和DEST-RT相比,PREP组在继时性加工上进步显著;在正字法选择,这一在单词加工中利用视觉-字形信息的正字法加工任务上,PREP组的表现也优于DEST-RT组;最后,在语音敏感性、字母数字的RAN、单词阅读(真词和假词)及段落理解等方面,PREP和DEST-RT的表现均显著优于CA-C和RA-C。讨论部分,则着重讨论设计理论驱动的低成本且能有效改善阅读表现的补救方案的必要性。 | Timothy C. Papadopoulos Pana yiota Kendeou 邓赐平(中文摘要翻译) | 2010 | 心理科学2010，33，6： | 2 |
| 4 | Experiments on speech and music signals transmission using chaos 显示文摘 | Dnutriev A S Panas A I Starkov S O | 1995 | Int J Bifurc Chaos1995，5，4： | 1 |
| 5 | Episodes of generalized weakness in two sibs with the C164T mutation of the connexin 32 gene显示文摘 | Kalfakis N Karadimas C | 2001 | Neurology2001，57，： | 1 |
| 6 | Adaptive reduction of heart sounds from lung sounds using fourth-order statistics 显示文摘 | Hadjileontiadis LJ Panas SM | 1997 | IEEE Transactions on Biomedical Engineering1997，44，7： | 1 |
| 7 | Effects of added surfactant on the dynamic interfacial tension behavior of acidic oil/alkaline systems显示文摘 | Touhami Y Pana D Hornof V | 2001 | Journal of Colloid and Interface Science2001，239，1： | 1 |
| 8 | Estimating Fractal Dimension Using Stable Distribution and Exploring Long Memory through ARFIMA Models in Athens Stock Exchange显示文摘 | Panas Epaminondas | 2001 | Applied Financial Economics2001，11，： | 1 |
| 9 | 查看详情显示文摘 | Pana C T Wanga C M Hsina Y M Zhub H J Kuob J M Kaob Y C | | 0，，： | 1 |
| 10 | On applying spatial constraints in fuzzy image clustering using a fuzzy rule-based system显示文摘 | Tolias Y A Panas S M | 1998 | IEEE Signal Process Lett1998，5，： | 1 |
| 11 | PAI-S/K: A robust auto-matic seismic P phase arrival identification显示文摘 | Saragiotis C H D Hadjileontiadis L J Panas S M | 2002 | IEEE Transactions on Geo-science and Remote Sensing2002，40，6： | 1 |
| 12 | How robust is the capital-skill complementarity hypothesis? 显示文摘 | BERGSTROM V PANAS E | 1992 | The Review of Eco- nomics and Statistics1992，74，3： | 1 |
| 13 | Estimating Fractal Dimension Using Stable Distributionsand Exploring Long Memory Through ARFIMA Models in Athens Stock Exchange显示文摘 | Panas E | 2001 | Applied Financial Economics2001，，11： | 1 |
| 14 | Microwave synthesis of magnetic Fea 04 nanoparticles used as precursor of nanocomposites and ferrofluids显示文摘 | HONG R Y PANA T T LI H Z | 2006 | Journal of Magnetism and Magnetic Materials2006，303，1： | 1 |
| 15 | Are oil markets chaotic? A non-lineardynamic analysis显示文摘 | Panas Epaminondas Ninni Vassilia | 2000 | Energy Economics2000，，22： | 1 |
| 16 | Development of reliable PCR based markers linked to downy mildew resistant genes in lettuce显示文摘 | Pana I Michmore R W | 1993 | Theoretical and Applied Genetics1993，85，： | 1 |
| 17 | ECG data compression using wavelets and higher order statistics methods显示文摘 | Istepanian R S Hadjileontiadis L J Panas S M | 2001 | Information Technology in Biomedicine IEEE Transactions on2001，5，2： | 1 |
| 18 | Synthesis of Nd2 Si2 07 ceramic pigmentwith LiCI as a mineralizer and its color property 显示文摘 | Shanjun Kea Yanmin Wanga Zhidong Pana | 2014 | Dyes and Pigments2014，108，： | 1 |
| 19 | Comparison of the rebound tonometer (ICare)to the applanation tonometer (Tononpen XL)in normotenaive dogs显示文摘 | Leiva M Naranjo C Pana MT | 2006 | Vet Ophthalmol2006，9，1： | 1 |
| 20 | Fuzzy vessel tracking algorithm for retinal images based on fuzzy clustering 显示文摘 | Tolias Y Panas S A | 1998 | IEEE Transmitting on Medical lrnage1998，17，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员