维普中文期刊产品整合服务
1篇 您的检索式:作者名="Lazaros Sideras"
    题名 作者 年代 出处 被引量
1Update on the association of hepatitis B with intrahepatic cholangiocarcinoma:Is there new evidence?显示文摘Intrahepatic cholangiocarcinoma(iCCA)is a subgroup of cholangiocarcinoma that accounts for about 10%-20%of the total cases.Infection with hepatitis B virus(HBV)is one of the most important predisposing factors leading to the formation of iCCA.It has been recently estimated based on abundant epidemiological data that the association between HBV infection and iCCA is strong with an odds ratio of about 4.5.The HBV-associated mechanisms that lead to iCCA are under intense investigation.The diagnosis of iCCA in the context of chronic liver disease is challenging and often requires histological confirmation to distinguish from hepatocellular carcinoma.It is currently unclear whether antiviral treatment for HBV can decrease the incidence of iCCA.In terms of management,surgical resection remains the mainstay of treatment.There is a need for effective treatment modalities beyond resection in both first-and second-line treatment.In this review,we summarize the epidemiological evidence that links the two entities,discuss the pathogenesis of HBV-associated iCCA,and present the available data on the diagnosis and management of this cancer.Nikolaos Fragkou Lazaros Sideras Panteleimon Panas Christos Emmanouilides Emmanouil Sinakos 2021World Journal of Gastroenterology2021,27,27:2
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费