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	题名	作者	年代	出处	被引量
1	Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoictic stem cell transplants: an international consensus显示文摘	Ascioglu S Rex JH de Panw B	2002	Clin Infect Dis2002，34，1：	1
2	Analysing the nano- porous structure of aramid fibres显示文摘	Panw B R Vigild M E Mortensen K	2010	J Appl Crystallogr2010，43，4：	1
3	Rapid collapse into a molten globule is followed by simple two-state kinetics in the folding of lysozyme from bacteriophage h 显示文摘	Di Paolo A Balbeur D De Panw E	2010	Biochemistry2010，49，39：	1
4	Formationofregularzig-zagbranchofCsClcrystallitesonglasssubstrate:Anewlateralgrowthmechanismleadingtolong-rangeordering显示文摘	PanW MaoYW ShuDJ etal	2007	Jour-nalofCrystalGrowth2007，307，1：	1
5	SubgroupJ a- vian leukosis virus in layer flocks in China显示文摘	GAOYL QINLT PANW	2010	Emerg Infect Dis2010，16，：	1
6	25dihydmxyvitaminD3 suppresses by blocking the activity of the cyclic AMP responseelement in the renin genepromoter 显示文摘	YuanW PanW KongJ	2007	BiolChem2007，282，：	1
7	Removal of NO by using fenton reagent solution in a lab - scale bubbling reactor 显示文摘	GuoRT PanW G ZhangX B	2011	Fuel2011，90，：	1
8	查看详情显示文摘	LinD.D WuH PanW		0，，：	1
9	Flexible multibody dynamic simulation using optimal lumped inertia matrices 显示文摘	PanW Haug E J	1999	Computer methods in applied mechanics and engineering1999，，17：	1
10	Syntheis and application of hepatitis E virus peptides to diagnosis 显示文摘	CuiD PanW etal	1995	Journal of Virology Methods1995，55，：	1
11	Incessant automatic atrial tachycardia: a reversible cause of tachycardiomyopathy 显示文摘	Tavernier R De Panw M Trouerbach J	1999	Acla Car- diol1999，54，4：	1
12	Prediction of SO2 removal efficiency for wet flue gas desulfurization 显示文摘	Dou B L PanW G Jin Q	2009	Energy Conversion and Management2009，50，：	1
13	Automated sample preparation-fraetionation for the measurement of dioxins and related compounds in biological matrices: a review显示文摘	Focant J F Pirard C De Panw E	2004	Talanta2004，63，5：	1
14	A novelmicrosensor fabricated with charge-flow transistor and a Langmuir-Blodgett organic semiconductor film 显示文摘	XieD JiangY PanW	2003	Thin Solid Films2003，424，2：	1
15	Tissue engineering concept in the research of the tumor biology 显示文摘	Xu W HuX PanW	2014	Technol Cancer Res Treat2014，13，2：	1
16	Effect of NazOontheRe- duction of Fe203 compacts With CO/CO2 显示文摘	PanW Ma Z J ZhaoZX etal	2012	Metallurgical and Materials Transactions B2012，43，6：	1
17	Value of the paced QRS duration 显示文摘	PanW SuY Gong X etal	2009	J Card Fail2009，15，4：	1
18	显示文摘	PanW Zhang X K Ma H Y	2008	J Phys Chem C2008，112，：	1
19	Vaccine candidate MSP-1 from Plasmodium falciparum: a redesigned 4917 bp polynucleotide enables synthesis and isolation of full-length protein from Escherichia coli and mammalian cells显示文摘	Ravot E Tolle R	1999	Nucl Acid Res1999，27，：	1
20	Fusion of two malaria vaccine candidate antigens enhances product yield, immunogenicity, and antibody-mediated inhibition of parasite growth in vitro显示文摘A Plasmodium falciparum chimeric protein 2.9 (PfCP-2.9) was constructed consisting of the C-terminal regions of two leading malaria vaccine candidates, domain Ⅲ of apical membrane ag-1 (AMA-1) and 19-kDa C-terminal fragment of the merozoite surface protein 1 (MSP1). The PfCP-2.9 was produced by Pichia pastoris in secreted form with a yield of 2 600 mg/L and approximately 1 g/L of final product was obtained from a three-step purification process. Analysis of conformational properties of the chimeric protein showed that all six conformational mABS interacted with the recombinant protein were reduction-sensitive, indicating that fusion of the two cysteine-rich proteins retains critical conformational epitopes. PfCP-2.9 was found to be highly immunogenic in rabbits as well as in rhesus monkeys (Macaca mulatta). The chimeric protein induced both anti-MSP1-19 and anti-AMA-1(Ⅲ) ABS at levels 11- and 18-fold higher, respectively, than individual components did. Anti-PfCP-2.9 sera from both rabbits and rhesus monkeys almost completely inhibited in vitro growth of the P.falciparum FCC1/HN and 3D7 lines when tested at a 6.7-fold dilution. It was shown that the inhibition is dependent on the presence of ABS to the chimeric protein and their disulfide bond-dependent conformations. Moreover, the activity was mediated by a combination of growth-inhibitory ABS generated by the individual MSP1-19 and AMA-1(Ⅲ) of PfCP-2.9. The combination of the extremely high yield of the protein and enhancement of its immune response provides a basis to develop an effective and affordable malaria vaccine.	PanW HuangD ZhangQ QuL ZhangD ZhangX XueX QianF	2005	第二军医大学学报2005，26，4：	1

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