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| 1 | Increased osteopontin and liver stiffness measurement by transient elastography in biliary atresia显示文摘AIM: To analyze plasma osteopontin levels and liver stiffness using transient elastography in postoperative biliary atresia (BA) children compared with healthy controls. METHODS: Thirty children with postoperative BA and 10 normal controls were enrolled. The patients were categorized into two groups according to their jaundicestatus. Plasma levels of osteopontin were determined using commercially available enzyme-linked immunosorbent assay. Liver stiffness was measured by using transient elastography (Fibroscan). Ten validated Fibroscan measurements were performed in each patient and control with the result expressed in kilopascals (kPa). RESULTS: Plasma osteopontin was significantly elevated in BA children compared with that of healthy controls (47.0 ± 56.4 ng/mL vs 15.1 ± 15.0 ng/mL, P = 0.01). The liver stiffness measurement was markedly elevated in the patients with BA compared with that of controls (26.9 ± 24.6 kPa vs 3.9 ± 0.7 kPa, P = 0.001). Subgroup analysis showed that the BA patients with jaundice had more pronounced plasma osteopontin levels than those without jaundice (87.1 ± 61.6 ng/mL vs 11.9 ± 6.1 ng/mL, P = 0.001). Furthermore, the mean liver stiffness was significantly greater in the jaundiced BA patients compared with non-jaundiced patients (47.7 ± 21.8 kPa vs 8.7 ± 3.0 kPa, P = 0.001). Additionally, plasma osteopontin was positively related to serum total bilirubin (r = 0.64, P < 0.001). There was also a correlation between plasma osteopontin and liver stiffness values (r = 0.60, P < 0.001). CONCLUSION: High plasma osteopontin positively correlated with degree of hepatic fibrosis and could be used as a biochemical parameter reflecting disease severity in postoperative BA children. | Sittisak Honsawek Maneerat Chayanupatkul Voranush Chongsrisawat Paisarn Vejchapipat Yong Poovorawan | 2010 | World Journal of Gastroenterology2010，16，43： | 8 |
| 2 | Novel mutations in the STK11 gene in Thai patients with Peutz-Jeghers syndrome显示文摘Peutz-Jeghers syndrome(PJS) ,a rare autosomal dominant inherited disorder,is characterized by hamartomatous gastrointestinal polyps and mucocutaneous pigmentation.Patients with this syndrome have a predisposition to a variety of cancers in multiple organs.Mutations in the serine/threonine kinase 11(STK11) gene have been identified as a major cause of PJS.Here we present the clinical and molecular findings of two unrelated Thai individuals with PJS.Mutation analysis by Polymerase Chain Reaction-sequencing of the entire coding region of STK11 revealed two potentially pathogenic mutations.One harbored a single nucleotide deletion(c.182delG) in exon 1 resulting in a frameshift leading to premature termination at codon 63(p.Gly61AlafsX63) .The other carried an in-frame 9-base-pair(bp) deletion in exon 7,c.907_915del9(p.Ile303_Gln305del) .Both deletions were de novo and have never been previously described.This study has expanded the genotypic spectrum of the STK11 gene. | Surasawadee Ausavarat Petcharat Leoyklang Paisarn Vejchapipat Voranush Chongsrisawat Kanya Suphapeetiporn Vorasuk Shotelersuk | 2009 | World Journal of Gastroenterology2009，15，42： | 8 |
| 3 | Synchronous gallbladder and pancreatic cancer associated with pancreaticobiliary maljunction显示文摘We report the case of a 46-year-old woman who presented with chronic intermittent abdominal pain without jaundice; abdominal ultrasonography showed thickening of the gallbladder wall and dilatation of the bile duct. Endoscopic retrograde cholangiopancreaticography showed pancreatobiliary maljunction with proximal common bile duct dilatation. Pancreatobiliary maljunction was diagnosed. A computed tomography scan of the abdomen showed suspected gallbladder cancer and distal common bile duct obstruction. A pancreatic head mass was incidentally found intraoperative. Radical cholecystectomy with pancreatoduodenectomy was performed. The pathological report showed gallbladder cancer that was synchronous with pancreatic head cancer. In the pancreatobiliary maljunction with pancreatobiliary reflux condition, double primary cancer of the pancreatobiliary system should be awared. | Narongsak Rungsakulkij Paisarn Boonsakan | 2014 | World Journal of Gastroenterology2014，20，39： | 2 |
| 4 | Serum hepatocyte growth factor and clinical outcome in biliary atresia显示文摘 | Paisarn Vejchapipat Apiradee Theamboonlers Rapeepan Chaokhonchai Voranush Chongsrisawat Soottiporn Chittmittrapap Yong Poovorawan | 2004 | Journal of Pediatric Surgery2004，，7： | 1 |
| 5 | A review of flow and heat transfer characteristics in curved tubes显示文摘 | Paisarn Naphon Somchai Wongwise | 2006 | Renewable and Sustainable Energy Review2006，10，5： | 1 |
| 6 | Investigation on the jet liquid impingement heat transfer for the central processing unit of personal computers显示文摘 | Paisarn Naphon Somchai Wongwises | 2012 | International Communications in Heat and Mass Transfer2012，37，7： | 1 |
| 7 | Effect of wavy plate geometry configurations on the temperature and flow distributions 显示文摘 | PAISARN NAPHON | 2009 | International Communications in Heat and Mass Transfer2009，36，： | 1 |
| 8 | Effect of wavy plate geometry configurations on the temperature and flow distributions显示文摘 | Paisarn N | 2009 | Int J International Communications in Heat and Mass Transfer2009，36，： | 1 |
| 9 | Heat pipe efficiency enhancement with re- frigerant - nanoparticles mixtures 显示文摘 | Paisarn Naphon Dithapong Thongkum Pichai Assad- amongkol | 2009 | Energy Conversion and Management2009，50，3： | 1 |
| 10 | Multiplex RT-PCR assay for simultaneous detection of six viruses of penaeid shrimp显示文摘 | Paisarn K Warin D Parin C | 2008 | Mol Cell2008，22，： | 1 |
| 11 | Formability of Magnesium Alloy Sheets Manufactured by Semi-Solid Roll stripCasting显示文摘 | Watari H Koga N Paisarn R | 2004 | Materials Science Forum2004，，： | 1 |
| 12 | Thermal performance and pressure drop of the helical-coil heat exchangers with and without helically crimped fins 显示文摘 | Naphon Paisarn | 2007 | International Communications in Heat and Mass Transfer2007，34，3： | 1 |
| 13 | Study on the exergy loss of the horizontal concentric micro-fin tube heat exchanger显示文摘 | PAISARN N | 2011 | Heat and Mass Transfer2011，38，2： | 1 |
| 14 | Tube side heat transfer coefficient and friction factor characteristics of horizontal tubes with helical rib 显示文摘 | PAISARN N MANACHAI N | 2006 | Energy Conversion and Management2006，47，18： | 1 |
| 15 | Development of monoclonal antibodies for simple detection and differentiation of Vibrio mimicus from V. cholerae and Vibrio spp. by dot blotting显示文摘 | Chalinan Pengsuk Siwaporn Longyant Sombat Rukpratanporn Parin Chaivisuthangkura Pattarin Sridulyakul Paisarn Sithigorngul | 2010 | Aquaculture2010，，1： | 1 |
| 16 | Numerical investigation on the heat transfer and flow in the mini-fin heat sink for CPU 显示文摘 | Paisarn Naphon Setha Klangchart Somchai Wongwises | 2009 | International Communica- tions in Heat and Mass Transfer2009，36，8： | 1 |
| 17 | Thermal performance and pressure drop of the helical-coil heat exchangers with and without helically crimped fins显示文摘 | PAISARN Naphon | 2007 | International Communications in Heat and Mass Transfer2007，34，3： | 1 |
| 18 | AZ31マグネシウム合金板の深绞り性に及ぽす工具ア-ルの影响显示文摘 | Ratchanee PAISARN 田川省吾 古闲伸裕 | 2003 | 轻金属2003，53，4： | 1 |
| 19 | Multiplex RT-PCR assay for simultaneous detection of six viruses of penaeid shrimp 显示文摘 | Paisarn Khawsak Warin Deesukon Parin Chaivisuthangkura et al | 2008 | Molecular and Cellular Probes2008，22，： | 1 |
| 20 | A review of flow and heat transfer characteristics in curved tubes显示文摘 | Paisarn Naphon Somchai Wongwises | 2004 | Renewable and Sustainable Energy Reviews2004，，5： | 1 |
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