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| 1 | Early endoscopic ultrasonography in acute biliary pancreatitis: A prospective pilot study显示文摘AIM: To investigate the clinical usefulness of early endoscopic ultrasonography(EUS) in the management of acute biliary pancreatitis(ABP).METHODS: All consecutive patients entering the emergency department between January 2010 and December 2012 due to acute abdominal pain and showing biochemical and/or radiological findings consistent with possible ABP were prospectively enrolled. Patients were classified as having a low,moderate,or high probability of common bile duct(CBD) stones,according to the established risk stratification. Exclusion criteria were: gastrectomy or patient in whom the cause of biliary obstruction was already identified by ultrasonography. All enrolled patients underwent EUS within 48 h of their admission. Endoscopic retrograde cholangiopancreatography was performed immediately after EUS only in those cases with proven CBD stones or sludge. The following parameters were investigated:(1) clinical: age,sex,fever;(2) radiological: dilated CBD; and(3) biochemical: bilirubin,AST,ALT,g GT,ALP,amylase,lipasis,PCR. Association between presence of CBD stone at EUS and the individual predictors wereassessed by univariate logistic regression. Predictors significantly associated with CBD stones(P < 0.05) were entered in a multivariate logistic regression model.RESULTS: A total of 181 patients with pancreatitis were admitted to the emergency department between January 2010 and December 2012. After exclusion criteria a total of 71 patients(38 females,53.5%,mean age 58 ± 20.12 years,range 27-89 years; 33 males,46.5%,mean age 65 ± 11.86 years,range 41-91 years) were included in the present study. The probability of CBD stones was considered low in 21 cases(29%),moderate in 26(37%),and high in the remaining 24(34%). The 71 patients included in the study underwent EUS,which allowed for a complete evaluation of the target sites in all the cases. The procedure was completed in a mean time of 14.7 min(range 9-34 min),without any notable complications.The overall CBD stone frequency was 44%(31 of 71),with a significant increase from the group at low pretest probability to that at moderate(OR = 5.79,P = 0.01) and high(OR = 4.25,P = 0.03) pretest probability.CONCLUSION: Early EUS in ABP allows,if appropriate,immediate endoscopic treatment and significant spare of unnecessary operative procedures thus reducing possible related complications. | Andrea Anderloni Marianna Galeazzi Marco Ballarè Michela Pagliarulo Marco Orsello Mario Del Piano Alessandro Repic | 2015 | World Journal of Gastroenterology2015，21，36： | 14 |
| 2 | Endowing a plain fluidic chip with micro-optics: a holographic microscope slide显示文摘Lab-on-a-Chip(LoC)devices are extremely promising in that they enable diagnostic functions at the point-of-care.Within this scope,an important goal is to design imaging schemes that can be used out of the laboratory.In this paper,we introduce and test a pocket holographic slide that allows digital holography microscopy to be performed without an interferometer setup.Instead,a commercial off-the-shelf plastic chip is engineered and functionalized with this aim.The microfluidic chip is endowed with micro-optics,that is,a diffraction grating and polymeric lenses,to build an interferometer directly on the chip,avoiding the need for a reference arm and external bulky optical components.Thanks to the single-beam scheme,the system is completely integrated and robust against vibrations,sharing the useful features of any common path interferometer.Hence,it becomes possible to bring holographic functionalities out of the lab,moving complexity from the external optical apparatus to the chip itself.Label-free imaging and quantitative phase contrast mapping of live samples are demonstrated,along with flexible refocusing capabilities.Thus,a liquid volume can be analyzed in one single shot with no need for mechanical scanning systems. | Vittorio Bianco Biagio Mandracchia Valentina Marchesano Vito Pagliarulo Federico Olivieri Sara Coppola Melania Paturzo Pietro Ferraro | 2017 | Light(Science & Applications)2017，6，1： | 6 |
| 3 | The influence of the geo-logical setting on the morphogenetic evolution of the TremitiArchipelago (Apulia, Southeastern Italy) 显示文摘 | Andriani G F Walsh N Pagliarulo R | 2005 | Natural Hazardsand Earth System Science2005，5，1： | 1 |
| 4 | CXCR4-CXCL12-dependent inflammatory network and endothelial progenitors显示文摘 | SALVATORE P PAGLIARULO C COLICCHIO R et-al | 2010 | Curr Med Chem2010，17，27： | 1 |
| 5 | Propranolol as first-line treatment of a severe subglottic haemangioma显示文摘 | Loizzi M De Palma A Pagliarulo V | 2013 | Eur J Cardiothorac Surg2013，43，1： | 1 |
| 6 | Gallstone disease and re- lated risk factors in a large cohort of diabetic patients 显示文摘 | Pagliarulo M Fomari F Fraquelli M | 2004 | Dig Liver Dis2004，36，2： | 1 |
| 7 | Gallbladder motility in obesity,diabetes mellitus, and coeliac disease显示文摘 | Fraquelli M Pagliarulo M Colucci A | 2003 | Dig Liver Dis2003，35，： | 1 |
| 8 | Probiotics: from research to consumer显示文摘 | M. Del Piano L. Morelli G.P. Strozzi S. Allesina M. Barba F. Deidda P. Lorenzini M. Ballaré F. Montino M. Orsello M. Sartori E. Garello S. Carmagnola M. Pagliarulo L. Capurso | 2006 | Digestive and Liver Disease2006，，： | 1 |
| 9 | Generation of a concise gene panel for outcome prediction in urinary bladder cancer显示文摘 | Mitra AP Pagliarulo V Yang D | 2009 | J Clin Oncol2009，27，24： | 1 |
| 10 | Generation of a concise gene panel for outcome prediction in urinary bladder cancer显示文摘 | Mitra AP Pagliarulo V Yang D | 2009 | J Clin Oneol2009，27，24： | 1 |
| 11 | Primary small noncleaved cell lymphoma of the kidney显示文摘 | Salem Y Pagliarulo LC Manyak MJ | 1993 | Urology1993，42，： | 1 |
| 12 | Paroxetine in the treatment of premature ejaculation显示文摘 | Corvasce A Pagliarulo G | 1996 | Br JUrol1996，77，6： | 1 |
| 13 | Generation of a concise gene panel for outcome prediction in urinary bladder cancer 显示文摘 | Mitra A P Pagliarulo V Yang D | 2009 | J Clin Oncol2009，27，24： | 1 |
| 14 | Gallbladder motility in obesity,diabetes mellitus and coeliac disease 显示文摘 | Fraquelli M Pagliarulo M Colucci M | 2003 | Dig Liver Dis2003，35，3： | 1 |
| 15 | Gallstone disease and related risk factors in a large cohort of diabetic patients 显示文摘 | Pagliarulo M Fornari F Fraquelli M | 2004 | Dig Liver Dis2004，36，2： | 1 |
| 16 | Contemporary role of androgen deprivation therapy for prostate cancer显示文摘 | Pagliarulo V Bracarda S Eisenberger MA | 2012 | Eur Uro12012，61，1： | 1 |
| 17 | Sexual dysfunctions in multiple sclerosis 显示文摘 | Dachille G Ludovico GM Pagliarulo G | 2008 | Minerva Urol Nefrol2008，60，： | 1 |
| 18 | Gallstone disease and related risk factors in a large cohort of diabetic patients显示文摘 | Pagliarulo M Fomari F Fraquelli M | 2004 | Dig Liver Dis2004，36，2： | 1 |
| 19 | Gallstone disease and related risk factors in a large cohort of diabetic patients显示文摘 | Pagliarulo M Fornari F FraqueIIi M | 2004 | Dig Liver Dis2004，36，2： | 1 |
| 20 | Influence of water recharge on heat transfer in a semi-infinite aquifer显示文摘 | Mongelli F Pagliarulo P | 1997 | Geothermics1997，26，3： | 1 |
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