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| 1 | 局灶节段透明变性及硬化在判断IgA肾病预后中的意义显示文摘目的 探讨IgA肾病 (IgAN)进展为慢性肾功能不全 (CRI)的病理学危险因素。方法 对 6 40例经肾活检确诊的IgAN病人进行平均 5 3个月的追踪观察。用病例对照法研究所有病人的病理学资料 ,同时还对其中 2 0 4例活检当时肾功能正常 ,5年后发展为CRI或终末期肾功能衰竭(ESRF) (n =18)以及 5年后肾功能仍保持正常 (n =186 )的病例进行了比较。结果 弥漫性系膜增生型 (DMP)为最常见的病理型 ,占 5 0 %。 / 间质纤维化 ,>40 %硬化肾小球 , / 血管病变 ,局灶节段透明变性及硬化 (FSHS)的均为预测肾功能恶化的危险因素 ,其中FSHS的意义更大 (P <0 0 0 0 1)。结论 FSHS的存在是IgAN病人正常肾功能进展恶化的显著指标。 | 严海东 Packham D Kincaid Smith P Becker G 周希静 | 1999 | 中华肾脏病杂志1999，15，5： | 20 |
| 2 | Regulation of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Burkittps lymphoma cell lines显示文摘 | Mouzakiti A Packham G | 2003 | Br J Haematol2003，122，1： | 1 |
| 3 | Selective regulation of Bel-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies显示文摘 | Packham G White EL Eisehen CM | 1998 | Genes Dev1998，12，16： | 1 |
| 4 | Chelating polymers derived from polyvinyl alcohol and cellulose显示文摘 | Gibson G K J packham P I | 1966 | J Appl Chem1966，16，： | 1 |
| 5 | A20 RNA expression is associated with undifferentiated nasopharyngcel carcinoma and poorly differentiated head and neck squamous cell carcinoma 显示文摘 | CODD J D SALISBURY J R PACKHAM G | 1999 | J Pathol1999，187，5： | 1 |
| 6 | Macrolactamization versus macrolactonization: total synthesis of FK228, the depsipeptide histone deacetylase inhibitor 显示文摘 | WEN S J PACKHAM G H GANESAN A | 2008 | J Org Chem2008，73，23： | 1 |
| 7 | Bcl-2 is an apoptotic target suppressed by both c-myc and E2F-1显示文摘 | EISCHEN C M PACKHAM G NIP J | 2001 | Oncogene2001，20，48： | 1 |
| 8 | A hypothesis for the formation of marginal seas in the western Pacific显示文摘 | Packham G H Falvey D A | 1971 | Tectonophysics1971，11，2： | 1 |
| 9 | Bodyguards and assassins: Bcl-2 family proteins and apoptosis control in chronic lym- phocytic leukaemia 显示文摘 | Packham G Stevenson FK | 2005 | Immunology2005，114，4： | 1 |
| 10 | Regulation of tomour necrosis factor-related apoptosis-inducing ligand(TRAIL)-induced apoptosis in Burkitt's lymphoma cell lines显示文摘 | Mouzakiti A Packham G | 2003 | Br J Haematol2003，122，1： | 1 |
| 11 | c-Myc and apoptosis显示文摘 | Packham G Cleveland J L | 1995 | Biochimica et Biophysica Acta1995，1242，： | 1 |
| 12 | Ornithine decarboxylase is a mediator ofC-myc-induced apoptosis显示文摘 | Packham G Cleveland JL | 1994 | Mol Cell Biol1994，14，9： | 1 |
| 13 | C-mycinducesapoptosis and cell cycle progression by separable, yet overlapping, pathways显示文摘 | Packham G Porter C W Cleveland J L | 1996 | Oncogene1996，13，3： | 1 |
| 14 | BAG-1:a multi-functional pro-survival molecule显示文摘 | Townsend PA Stephanou A Packham G | 2005 | Int J Biochem Cell Biol2005，37，2： | 1 |
| 15 | BAG-1 : a multifunctional pro-survival molecule显示文摘 | Townsend P A Stephanou A Packham G | 2005 | Int J Biochem Cell Biol2005，37，2： | 1 |
| 16 | BAG-1:a multi-functional pro-survival molecule显示文摘 | TOWNSEND P A STEPHANOU A PACKHAM G | 2005 | Int J Biochem Cell Biol2005，37，2： | 1 |
| 17 | The ornithine decarboxylase gene is a transcriptional target of c-Myc显示文摘 | Bello-Fernandez C Packham G Cleveland JL | 1993 | Proc Natl Acad Sci USA1993，90，： | 1 |
| 18 | Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis显示文摘 | Packham G Cleveland J L | 1994 | Mol Cell Biol1994，14，： | 1 |
| 19 | Student Attitudes towards Enterprise Education in Poland:A Positive Impact显示文摘 | Jones P Jones A Packham G Miller C | | 0，，07： | 1 |
| 20 | BAG-1:a multi-functional pro-survival molecule显示文摘 | TOWNSEND PA STEPHANOU A PACKHAM G | 2005 | Int J Biochem Cell Biol2005，37，2： | 1 |
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