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| 1 | Spontaneous transformation of human adult non-tumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma显示文摘 | Shims A Chettiar S Shepal V Rajendran G Prasad R Shastry P | 2007 | 中国神经肿瘤杂志2007，5，1： | 16 |
| 2 | Miniature gastrointestinal endoscopy: Now and the future显示文摘Since its original application,gastrointestinal(GI)endoscopy has undergone many innovative transformations aimed at expanding the scope,safety,accuracy,acceptability and cost-effectiveness of this area of clinical practice.One method of achieving this has been to reduce the caliber of endoscopic devices.We propose the collective term“Miniature GI Endoscopy”.In this Opinion Review,the innovations in this field are explored and discussed.The progress and clinical use of the three main areas of miniature GI endoscopy(ultrathin endoscopy,wireless endoscopy and scanning fiber endoscopy)are described.The opportunities presented by these technologies are set out in a clinical context,as are their current limitations.Many of the positive aspects of miniature endoscopy are clear,in that smaller devices provide access to potentially all of the alimentary canal,while conferring high patient acceptability.This must be balanced with the costs of new technologies and recognition of device specific challenges.Perspectives on future application are also considered and the efforts being made to bring new innovations to a clinical platform are outlined.Current devices demonstrate that miniature GI endoscopy has a valuable place in investigation of symptoms,therapeutic intervention and screening.Newer technologies give promise that the potential for enhancing the investigation and management of GI complaints is significant. | John J McGoran Mark E McAlindon Prasad G Iyer Eric J Seibel Rehan Haidry Laurence B Lovat Sarmed S Sami | 2019 | World Journal of Gastroenterology2019，25，30： | 4 |
| 3 | Assessment of the diagnostic performance and interobserver variability of endocytoscopy in Barrett's esophagus:A pilot ex-vivo study显示文摘AIM:To investigate a classification of endocytoscopy(ECS)images in Barrett’s esophagus(BE)and evaluate its diagnostic performance and interobserver variability.METHODS:ECS was applied to surveillance endoscopic mucosal resection(EMR)specimens of BE ex-vivo.The mucosal surface of specimen was stained with 1%methylene blue and surveyed with a catheter-type endocytoscope.We selected still images that were most representative of the endoscopically suspect lesion and matched with the final histopathological diagnosis to accomplish accurate correlation.The diagnostic performance and inter-observer variability of the new classification scheme were assessed in a blinded fashion by physicians with expertise in both BE and ECS and inexperienced physicians with no prior exposure to ECS.RESULTS:Three staff physicians and 22 gastroenterology fellows classified eight randomly assigned unknown still ECS pictures(two images per each classification)into one of four histopathologic categories as follows:(1)BEC1-squamous epithelium;(2)BEC2-BE without dysplasia;(3)BEC3-BE with dysplasia;and(4)BEC4-esophageal adenocarcinoma(EAC)in BE.Accuracy of diagnosis in staff physicians and clinical fellows were,respectively,100%and 99.4%for BEC1,95.8%and83.0%for BEC2,91.7%and 83.0%for BEC3,and95.8%and 98.3%for BEC4.Interobserver agreement of the faculty physicians and fellows in classifying each category were 0.932 and 0.897,respectively.CONCLUSION:This is the first study to investigate classification system of ECS in BE.This ex-vivo pilot study demonstrated acceptable diagnostic accuracy and excellent interobserver agreement. | Yutaka Tomizawa Prasad G Iyer Louis M Wongkeesong Navtej S Buttar Lori S Lutzke Tsung-Teh Wu Kenneth K Wang | 2013 | World Journal of Gastroenterology2013，19，46： | 2 |
| 4 | Modular product design: A life cycle view 显示文摘 | GERSHENSON J K PRASAD G J ALLAMNENI S | 1999 | Journal of Integrated Design and Process Science1999，3，4： | 1 |
| 5 | Promoter hypermethylation of TMS1, BRCA1, ERa and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients 显示文摘 | Mirza S Sharma G Prasad CP | 2007 | Life Sciences2007，81，4： | 1 |
| 6 | Experimen- tal study of an air-cooled thermal rnanagement system for high capacity lithium-titanate batteries 显示文摘 | Giuliano M R Ajay Prasad K Advani S G | 2012 | Journal of Power Sources2012，216，： | 1 |
| 7 | Micro- structural Modeling of Metadynamic Recrystallization in Hot Working of In718 Superalloy 显示文摘 | Medeiros S C Prasad Y V R K Frazier W G | 2000 | Materials Science and Engineering2000，293，： | 1 |
| 8 | Combined Interpolation Restoration of Land-sat Images Through FIR Filter Design Techniques显示文摘 | Fonseca L M G Prasad G S D Mascarenhas N D A | 1993 | International Journal of Remote Sensing1993，14，13： | 1 |
| 9 | Micro- structural Modeling of Metadynamic Recrystallization in Hot Working of IN 718 Superalloy 显示文摘 | Medeiros S C Prasad Y V T K Frazier W G | 2000 | Materials Science and Engi- neering2000，293，12： | 1 |
| 10 | 显示文摘 | He G S Przemyslaw P M Prasad P N | 2002 | Nature2002，415，： | 1 |
| 11 | 查看详情显示文摘 | Bhawalkar J D He G S Prasad P N | | 0，，： | 1 |
| 12 | Ultra-fine grained AI-SiC metal matrix composite by rotary swaging process 显示文摘 | GIRIBASKAR S GOUTHAMA G PRASAD R | 2011 | Materials Science Forum2011，，： | 1 |
| 13 | Mitigating nitrous oxide and methane emissions from soil in rice-wheat system of the Indo-Gangetic plain with nitrification and urease inhibitors显示文摘 | Malla G Bhatia A Pathak H Prasad S Jain N Singh J | 2005 | Chemosphere2005，58，2： | 1 |
| 14 | Miscibility studies of poly saccharide xanthan gurs/PVP blend 显示文摘 | Guru G S Prasad P Shivakumar H R | 2010 | Journal Polymers and the Environ ment2010，18，2： | 1 |
| 15 | Formation and spreading of Arabian Sea high-salinity water mass显示文摘 | KUMAR S P PRASAD T G | 1999 | Journal of Geophysical Research1999，104，1： | 1 |
| 16 | Identification of keratins18,19 and heat-shock protein 90 beta as candidate substrates of proteolysis during ionizing radiation-induced apoptosis of estrogen-receptor negative breast tumor cells显示文摘 | PRASAD S SOLDATENKOV V A SRINIVASARAO G | 1998 | Int J Oncol1998，13，4： | 1 |
| 17 | Utilization of com steep liquor for biosynthesis of pullulan,an important exopolysaccharide显示文摘 | SHARMA N PRASAD G S CHOUDHURY A R | 2013 | Carbohydrate Polymers2013，93，1： | 1 |
| 18 | Unstable flow during supratransus working of Ti-6Al-4V 显示文摘 | SESHACHARYULU T MEDEIROS S C FRAZIER W G PRASAD Y V R K | 2001 | Materials Letters2001，47，： | 1 |
| 19 | A comparative study of tribological behavior of plasma and D-Gun sprayed coatings under different wear modes显示文摘 | G Sundararajan K U M Prasad D S Rao S V Joshi | 1998 | Journal of Materials Engineering and Performance1998，7，3： | 1 |
| 20 | Shaking table tests in earthquake geotechnical engineering显示文摘 | Prasad S K Towhata I Chandradhara G P | 2004 | Current Science2004，87，10： | 1 |
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