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| 1 | Pharmacognostic study and anti-inflammatory activity of Callistemon lanceolatus leaf显示文摘Objective:To study detail pharmacognosy and anti-inflammatory activity of Callistemon lanceolatus(C.lanceolatus) leaf.Methods:Leaf sample was studied by organoleptic, macroscopical,microscopical,phytochemical and other WHO recommended methods for standardizations.The methanolic leaf extract of the plant was also screened for antiinflammatory activity on carrageenan-induced paw edema in rat at doses of 200 and 400 mg/kg, orally.The detail pharmacognostic study of the C.lanceolatus leaf was carried out to lay down the standards which could be useful in future experimental studies.Results:C.lanceolatus methanolic leaf extract showed significant(P<0.0S) anti-inflammatory activity at doses of 200 mg/kg and 400 mg/kg.This significant anti-inflammatory of C.lanceolatus methanolic leaf extract at the dose of 400 mg/kg was comparable with diclofenac sodium.Conchuioiis:The pharmacognostic profile of the C.lanceolatus leaf is helpful in standardization for quality,purity and sample identification.The methanolic extract at a dose of 400 mg/kg shows a significant activity in comparison with the standard drug diclofenac sodium(50 mg/kg). | Kumar S Kumar V Prakash OM | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，3： | 10 |
| 2 | Antidiabetic and hypolipidemic activities of Kigelia pinnata flowers extract in streptozotocin induced diabetic rats显示文摘Objective:To evaluate antidiabetic and hypolipidemic activities of Kigelia pinnata rnethanolic(lowers extract in slreplozolocin(STZ) induced diabetic W islar rat.Methods.Rats were made diabetic by a single dose of STZ at 60 mg/kg body weight i.p.The blood glucose level was checked before and 72 h after STZ injection to confirm the development ot diabetes.The flower extract and glibenclamide were administered orally at the doses of 250 and 500 mg/kg body weight for 21 days.Results:Daily oral treatment with the extract and standard drug for 21 days significantly reduced blood glucose,serum cholesterol and triglycerides levels.High density lipoprotein-cholesterol level was found to be improved(P<0.01) as compared to diabetic control group.Conclusions:It is concluded that Kigellia pinnata flowers extract have significant antidiabetic and hypolipidemic effect. | Kumar S Kumar V Prakash OM | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，7： | 4 |
| 3 | Antidiabetic and anti-lipemic effects of Cassia siamea leaves extract in streptozotocin induced diabetic rats显示文摘Objective:To investigate the antidiabetic and anti-lipemic effects of Cassia siamea methanolic leaves extract.Methods:The antidiabetic study was performed by measuring blood glucose level with elegance glucometer at weekly intervals i.e.0,7,14 and 21 in normal and streptozotocin induced diabetic rats.Total cholesterol,triglyceride and HDL-cholesterol were determined in normal and streptozotocin induces diabetic rats by autoanalyser.Glibenclamide was used as a reference drug at a dose of 10 mg/kg.Results:After the oral administration of extracts at doses of 250 mg/kg and 500 mg/kg for three weeks,blood glucose levels and body weights were significantly improved(P<0.01).Daily oral treatment with the extract also resulted in significantly reduction of serum cholesterol and triglycerides.HDL-cholesterol level was found to be improved to(P<0.01).Conclusions:The Cassia siamea leaf extract is useful in controlling blood glucose level as well as improving lipid metabolism and body weight in rats with induced diabetes. | S Kumar V Kumar Om Prakash | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，11： | 3 |
| 4 | Morpho-anatomical and physicochemical studies of Fumaria indica(Hausskn.)Pugsley显示文摘Objective:To study morpho-anatomical characters and physicochemical analysis of Fumaria indica(F.indica)(Hausskn.)Pugsley,(Fumariaceae),an important medicinal plant used extensively for treating a variety of ailments in various system of indigenous medicine.Methods:Evaluation of the different parts of the plant was carried out to determine the morphoanatomical,physicochemical,phytochemical and HPTLC fingerprinting profile of F.indica and other WHO recommended methods were performed for standardization.Results:Morphoanatomical studies showed compound and pinnatifid leaf,4 to 6 cm in length,linear and oblong in shape and anomocytic arrangement of stomata,thin walled parenchymatous cells,scattered,sclerenchymatous,capped vascular bundles and radiating medullary rays.Physicochemical studies showed foreign matter 0.2%,loss on drying 6.8%,total ash 16.77%,alcohol and water soluble extractives 8.92%and 20.26%,respectively,sugar 17.75%,starch 22.97%and tannins 2.37%.Phytochemical evaluation revealed the presence of carbohydrate,alkaloids,flavonoids,saponins,tannins and sterol.Thin layer chromatography was carried out with different solvents and the best solvent system was chloroform and methanol in 80:20 ratio and revealed 12 spots with different R_f value under UV light 366λ.Conclusions:The results of the study can serve as a valuable source of information and provide suitable standards for identification of this plant material for future investigations and applications. | Prakash Chandra Gupta Ch V Rao | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，10： | 2 |
| 5 | A review on ethnobotany,phytochemistry and pharmacology of Fumaria indica(Fumitory)显示文摘Fumaria indica(Hausskn.) Pugsley(Fumariaceae),known as 'Fumitory',is an annual herb found as a common weed all over the plains of India and Pakistan.The whole plant is widely used in traditional and folkloric systems of medicine.In traditional systems of medicine,the plant is reputed for its anthelmintic,diuretic,diaphoretic,laxative,cholagoguc,stomachic and sedative activities and is used to purify blood and in liver obstruction in ethnopharmacology. The whole plant is ascribed to possess medicinal virtues in Ayurvedic and Unani systems of medicine and is also used in preparation of important Ayurvedic medicinal preparations and polyhedral liver formulations.The review reveals that phytochemical constituents of wide range have been separated from the plants and it possesses important pharmacological activities like smooth muscle relaxant,spasmogenic and spasmolytic,analgesic,anti-inflammatory, neuropharmacological and antibacterial activities.The separation of hepatoprotective and antifungal constituents from this plant was also reported newly.This review highlights the traditional,ethnobotanical,phytochemical,pharmacological information available on Fumaria indica,which might be helpful for scientists and researchers to find out new chemical entities responsible for its claimed traditional uses. | Prakash Chandra Gupta Nisha Sharma Ch V Rao | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，8： | 2 |
| 6 | Characteristic basis function method: a new technique for efficient solution of method of moments matrix equations显示文摘 | PRAKASH V V S MITTRA R | 2003 | Microwave and Optical Technology Letter2003，36，2： | 1 |
| 7 | Maternal and neonatal effects of bolus administration of ephedrine and phenylephrine during spinal anaesthesia for caesarean delivery : a randomized study 显示文摘 | Prakash S Pramanik V Chellani H | 2009 | Int J Obstet Anesth2009，19，1： | 1 |
| 8 | A fixed grid numerical modeling method-ology for convection-diffusion mushy region phase change prob-lems显示文摘 | Voller V R Prakash C | 1987 | Int J Heat Mass Tran1987，30，8： | 1 |
| 9 | Tuning the reactivity of energetic nanoparticles by creation of a core-shell nanostructure显示文摘 | Prakash A Mccormick A V Zachariah M R | | 0，，07： | 1 |
| 10 | Sustainability under combined application of mineral and organic fertilizers in a rained soybean-wheat system of the Indian Himalayas 显示文摘 | Bhattacharyya R Kundu S Prakash V Gupta H S | 2008 | European Journal of Agronomy2008，28，1： | 1 |
| 11 | Numerical solution of temperature- dependent thermal conductivity problems using a meshless method 显示文摘 | Singh A Singh I V Prakash R | 2006 | Numerical Heat Transfer Part B: Fundamentals2006，50，2： | 1 |
| 12 | Synthesis and antifungal activity of some neroxyl-2-(1-phenyl-3-aryl-4-pyrazolyl) chromones显示文摘 | Prakash O Kumar R Parkash V | 2008 | Eur J Med Chem2008，43，： | 1 |
| 13 | Aromatic Nitration With Nitric Acid/Trifluoromethanesulfonic Anhydide显示文摘 | George A Olak V Prakash Reddy G K Surya Prakash | 1992 | Synthesis1992，11，： | 1 |
| 14 | Efficient analysis of aclass of microstrip antennas using the characteristic basisfunction method (CBFM) 显示文摘 | Yeo J Prakash V V S Mittra R | 2003 | Microwave and OpticalTechnology Letters2003，39，6： | 1 |
| 15 | Atorvastatin protects against ischemia-reperfusion injury in fructose-induced insulin resistant rats显示文摘 | Prakash P Khanna V Singh V | | 0，，04： | 1 |
| 16 | Time-resolved friction with applications to high-speed machining:Experimental observations 显示文摘 | Prakash V | 1998 | Tri- bol Trans1998，41，2： | 1 |
| 17 | Biochemical and molecular alterations following arsenic-induced oxidative stress and mitochondrial dysfunction in rat brain显示文摘 | PRAKASH C SONI M KUMAR V | 2015 | Biol Trace Elem Res2015，167，1： | 1 |
| 18 | The modeling of heat, mass and solute transport in solidification systems显示文摘 | Voller V R Brent A D Prakash C | 1989 | International Journal of Heat and Mass Transfer1989，32，9： | 1 |
| 19 | Electroosmotic flow behaviour of metal contaminated expansive soil显示文摘 | Sivapullaiah P V Nagendra Prakash B S | 2007 | Journal of Hazardous Materials2007，143，3： | 1 |
| 20 | Maternal and neonatal effects of bolus administration of ephedrine and phenylephrine dur- ing spinal anaesthesiafor caesarean delivery: a randomised study 显示文摘 | Prakash S Pramanik V Chellani H | 2010 | Int J Obstet Anesth2010，19，1： | 1 |
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