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| 1 | Severe scrub typhus infection: Clinical features, diagnostic challenges and management显示文摘Scrub typhus infection is an important cause of acute undifferentiated fever in South East Asia. The clinical picture is characterized by sudden onset fever with chills and non-specific symptoms that include headache, myalgia, sweating and vomiting. The presence of an eschar, in about half the patients with proven scrub typhus infection and usually seen in the axilla, groin or inguinal region, is characteristic of scrub typhus. Common laboratory findings are elevated liver transaminases, thrombocytopenia and leukocytosis. About a third of patients admitted to hospital with scrub typhus infection have evidence of organ dysfunction that may include respiratory failure, circulatory shock, mild renal or hepatic dysfunction, central nervous system involvement or hematological abnormalities. Since the symptoms and signs are non-specific and resemble other tropical infections like malaria, enteric fever, dengue or leptospirosis, appropriate laboratory tests are necessary to confirm diagnosis. Serological assays are the mainstay of diagnosis as they are easy to perform; the reference test is the indirect immunofluorescence assay(IFA) for the detection of Ig M antibodies. However in clinical practice, the enzyme-linked immuno-sorbent assay is done due to the ease of performing this test and a good sensitivity and sensitivity when compared with the IFA. Paired samples, obtained at least two weeks apart, demonstrating a ≥ 4 fold rise in titre, is necessary for confirmation of serologic diagnosis. The mainstay of treatment is the tetracycline group of antibiotics or chloramphenicol although macrolides are used alternatively. In mild cases, recovery is complete. In severe cases with multi-organ failure, mortality may be as high as 24%. | John Victor Peter Thomas I Sudarsan John Anthony J Prakash George M Varghese | 2015 | World Journal of Critical Care Medicine2015，4，3： | 13 |
| 2 | Lower gastrointestinal bleeding: Association with Sevelamer use显示文摘Stercoral ulceration results from impaction of hard fecal mass on the colonic wall and is a relatively unknown cause of lower gastrointestinal bleeding. In this report, we describe a case of lower gastrointestinal bleeding due to stercoral ulceration resulting from Sevelamer, a drug which is commonly associated with constipation. | Pankaj Madan Suverta Bhayana Prakash Chandra John I Hughes | 2008 | World Journal of Gastroenterology2008，14，16： | 3 |
| 3 | Numerical solution of temperature- dependent thermal conductivity problems using a meshless method 显示文摘 | Singh A Singh I V Prakash R | 2006 | Numerical Heat Transfer Part B: Fundamentals2006，50，2： | 1 |
| 4 | Future molecular approaches to the diagnosis and treatment of glomerular disease 显示文摘 | Alcorta DA Prakash K Waga I | 2000 | Semin Nephrol2000，20，1： | 1 |
| 5 | In vitro inhibition of proliferation of estrogen-dependent and estrogen-independent human breast cancer cells treated with carotenoids or retinoids显示文摘 | Prakash P Russell R M Krinsky N I | 2001 | The Journal of Nutrition2001，131，： | 1 |
| 6 | Preparation and characterization of nanocrystaUite size cuprous oxide 显示文摘 | PRAKASH I MURALIDHARAN P NALLAMUTHU N | 2007 | Materials Research Bulletin2007，42，： | 1 |
| 7 | Dynamics of retrieval strategies for remote memories显示文摘 | Goshen I Brodsky M Prakash R | 2011 | Cell2011，147，3： | 1 |
| 8 | The Role of Energy in Real Business Cycle Models 显示文摘 | Kim I M Prakash L | 1992 | Journal of Monetary Economics1992，29，： | 1 |
| 9 | Meshless element free Galerkin method for unsteady nonlinear heat transfer problems 显示文摘 | Singh A Singh I V Prakash R | 2007 | International Journal of Heat and Mass Transfer2007，50，56： | 1 |
| 10 | Isolation and NMR spectral as- signments of steviolbioside and stevioside 显示文摘 | Chaturvedula V S P Prakash I | 2011 | International Journal of Research in Ayurveda & Pharmacy2011，2，4： | 1 |
| 11 | Meshless element free Galerkin method for unsteady nonlinear heat transfer problems 显示文摘 | SINGH A SINGH I V PRAKASH R | 2007 | Inter- national Journal of Heat and Mass Transfer2007，50，5： | 1 |
| 12 | Long-term concentrative meditation and cognitive performance among older adults显示文摘 | Prakash R Rastogi P Dubey I | 2012 | Neuropsychol Dev Cogn B Aging Neuropsychol Cogn2012，19，4： | 1 |
| 13 | Exercise training increases size of hippocampus and improves memory 显示文摘 | ERICKSON K I VOSS M W PRAKASH R S et al | 2011 | Proc Natl Aead Sci U S A2011，108，7： | 1 |
| 14 | A molecular approach to the study of genic heterozygosity in natural populations 1V patterns of genic variation in central, marginal and isolated populations of drosophila pseudoobscura显示文摘 | Prakash S Lewoptin R C Hubby J I | 1969 | Genetic1969，61，： | 1 |
| 15 | Comparative evaluation of cell proliferative indices and epidermal growth factor receptor expression in gastric careinoma 显示文摘 | Prakash I Mathur RP Kar P | 1997 | Indian J Pathol Mierobiol1997，40，4： | 1 |
| 16 | Comparative evaluation of cell proliferative indices and epidermal growth factor receptor expression in gastric carcinoma显示文摘 | Prakash I Mathur RP Kar P | 1997 | Indian J Pathol Microbiol1997，40，4： | 1 |
| 17 | Ex- ercise training increases size of hippocampus and im- proves memory显示文摘 | Erickson K I Voss M W Prakash R S | 2011 | Proc Natl Acad Sci U S A2011，108，7： | 1 |
| 18 | Implant strategies for endocervical and interstitial ultrasound hyperthermia adjunct to HDR brachytherapy for the treatment of cervical cancer显示文摘 | Wootton J H Prakash P Hsu I J | | 0，，13： | 1 |
| 19 | High-energy cathode material for long-life and safe lithium batteries 显示文摘 | SUN Y K MYUNG S T PARK B C PRAKASH J BELHAROUAK I AMINE K | 2009 | Nat Mater2009，8，： | 1 |
| 20 | Meshless analysis of unsteady-state heat transfer in semi-infinite solid with temperature-dependent thermal conductivity 显示文摘 | Singh A Singh I V Prakash R | 2006 | International Journal of Heat and Mass Transfer2006，33，2： | 1 |
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