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| 1 | Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice显示文摘AIM: To study isolation and chemical characterization of pectin derived from the common cranberry Vaccinium oxycoccos L. (oxycoccusan OP) and the testing of its preventive effect on experimental colitis.METHODS: Mice were administrated orally with OP two days prior to a rectal injection of 5% acetic acid and examined for colonic damage 24 h later. Colonic inflammation was characterized by macroscopical injury and enhanced levels of myeloperoxidase activity measured spectrophotometrically with o-phenylene diamine as the substrate. The mucus contents of the colon were determined by the Alcian blue dye binding method. Vascular permeability was estimated using 4% Evans blue passage after i.p. injection of 0.05 mol/L acetic acid. RESULTS: In the mice treated with OP, colonic macroscopic scores (1.1 ± 0.4 vs 2.7, P < 0.01) and the total square area of damage (10 ± 2 vs 21 ± 7, P < 0.01) were significantly reduced when compared with the vehicle-treated colitis group. OP was shown to decrease the tissue myeloperoxidase activity in colons (42 ± 11 vs 112 ± 40, P < 0.01) and enhance the amount of mucus of colitis mice (0.9 ± 0.1 vs 0.4 ± 0.1, P < 0.01). The level of colonic malondialdehyde was noted to decrease in OP-pretreated mice (3.6 ± 0.7 vs 5.1 ± 0.8, P < 0.01). OP was found to decrease the inflammatory status of mice as was determined by reduction of vascular permeability (161 ± 34 vs 241 ± 21, P < 0.01). Adhesionof peritoneal neutrophils and macrophages was also shown to decrease after administration of OP (141 ± 50 vs 235 ± 37, P < 0.05).CONCLUSION: Thus, a preventive effect of pectin from the common cranberry, namely oxycoccusan OP, on acetic acid-induced colitis in mice was detected. A reduction of neutrophil infiltration and antioxidant action may be implicated in the protective effect of oxycoccusan. | Sergey V Popov Pavel A Markov Ida R Nikitina Sergey Petrishev Vasily Smirnov Yury S Ovodov | 2006 | World Journal of Gastroenterology2006,12,41: | 9 |
| 2 | 氧消耗和二氧化碳恢复期动力学对冠状动脉疾病严重性和结局的预测价值显示文摘血管重塑似乎只对高度缺血的患者有益。该研究调查了在心肺功能运动试验(eardiopulmonary exercisetest,CPET)恢复期中气体分析预测冠状动脉疾病(coronary artery disease,CAD)严重性和预后的价值。方法:研究者研究了40例白人患者(21.2%女性),平均年龄(63.5±7.6)岁,有显著冠状动脉损伤(≥50%)。 | 黄洁 叶鹏 Popovic D Martic D Djordjevic T Pesic V Guazzi M Myers J Mohebi R Arena R | 2017 | 中华高血压杂志2017,25,10: | 5 |
| 3 | 热处理对类金刚石碳薄膜力学和摩擦性能的影响显示文摘利用直流磁分离及脉冲阴极双激发源等离子弧薄膜沉积装置制备了含Ti底层和无Ti底层的类金刚石碳薄膜(DLC);采用纳米硬度计、原子力显微镜和X射线光电子能谱仪分析了薄膜的力学性能和结构;采用УСК-1型球-盘滑动摩擦磨损试验机考察了薄膜的摩擦性能.结果表明,同无Ti底层的DLC薄膜相比,含Ti底层的DLC薄膜的硬度和弹性模量较低;含Ti底层的DLC薄膜经真空400℃退火后表面层中存在TiO2,内部存在TiC;而无Ti底层的DLC薄膜经真空500℃退火处理后硬度、弹性模量和表面形貌几乎保持不变;无Ti底层的DLC薄膜经空气中500℃退火后摩擦系数明显降低,这是由于DLC薄膜在空气中热处理时更易发生石墨化所致. | 江晓红 金元生 KAZACHENKO V P POPOV A N ROGACHEV A V | 2004 | 摩擦学学报2004,24,3: | 4 |
| 4 | Late miocene to pliocene paleogeography of the Paratethys and its relation to the Mediterranean显示文摘 | PoPov S V IRINA G S LUBOV B I | 2006 | Pataeogeography Palaeoclimatology Palaeoecology2006,238,: | 1 |
| 5 | Predicting the dispersion hardening effect in ferrite-pearlite normalized steels modified with vanadium显示文摘 | Popov V V Goldshteyn M I Akselrod A Y | 1990 | Phys Met & Metall1990,70,1: | 1 |
| 6 | Schwinger mechanism of electron positron pair production by the field of optical and X-ray lasers in vacuum显示文摘 | Popov V S | 2001 | JETP Lett2001,74,3: | 1 |
| 7 | Increasing the Efficiency of Diamond Edging of Flat Glass 显示文摘 | A V Popov | 2009 | Stekloi Keramika2009,,6: | 1 |
| 8 | Antiinflammatory activity of the pectic polysaccharide from Comarum palustre显示文摘 | POPOV S V POPOVA G Y OVODOVA R G | 2005 | Fitoterapia2005,76,34: | 1 |
| 9 | GH-releasing hormone and TH-releasing peptide-6 for diagnostic testing in GH-deficient adults显示文摘 | Popovic V Leal A Micic D | 2000 | Lancet2000,356,: | 1 |
| 10 | Computation of very fast transient overvoltages in transformer windings显示文摘 | Popov M Sluis L V D Paap G C | 2003 | IEEE Transactions on Power Delivery2003,18,4: | 1 |
| 11 | Hypopituitarism as a consequence of traumatic brain injury (TBI) and its possible relation with cognitive disabilities and mental distress 显示文摘 | Popovic V Pekic S Pavlovic D | 2004 | J Endocrinol Invest2004,27,11: | 1 |
| 12 | Carbon nanotubes: properties and application 显示文摘 | POPOV V N | 2004 | Materials Science and Engineering R: Reports2004,43,3: | 1 |
| 13 | Luminescent pro-perties of PP and LI)PE films and rods doped with the Eu(111 )-La( HI) complex显示文摘 | Pogreb R Popov O Lirtsman V | 2006 | Polym Adv Technol2006,,3: | 1 |
| 14 | Electroencephalography in status epilepticus in sleep (ESES) in various clinical pictures显示文摘 | Popovic Miocinovi c L Durrigl V Kapitanovic Vidak H | 2005 | Acta Med Croatica2005,59,1: | 1 |
| 15 | Levodopa and Aspirin Pretreatment Beneficial in Experimental Decompression Sickness 显示文摘 | Popovic P Popvic V Honeycutt | 1982 | Proc Soc Exp Biol Med1982,169,1: | 1 |
| 16 | Translocation of the novel cytokine HMGB1 to the cytoplasm and extracellular space coincides with the peak of clinical activity in experimentally UV-induced lesions of cutaneous lupus erythematosus显示文摘 | Barkauskaite V Ek M Popovic K | 2007 | Lupus2007,16,10: | 1 |
| 17 | Effect of intensivefunctional electrical stimulation therapy on upper-limb motorrecovery after stroke : case study of a patient with chronic stroke显示文摘 | Kawashima N Popovic MR Zivanovic V | 2013 | Physiother Can2013,65,1: | 1 |
| 18 | Transformation of tobacco with a gene for the thermophilic acyl-lipid desaturase enhances the chilling tolerance of plants显示文摘 | ORLOVA IV SEBEBRIISKAYA TS POPOV V | 2003 | Plant Cell Physiology2003,44,4: | 1 |
| 19 | Translocation of the novel cytokine HMGB1 to the cytoplasm and extracellular space coincides with the peak of clinical activity in experimentally UV-induced lesions of cutaneous lupus erythematosus 显示文摘 | Barkauskaite V Ek M Popovic K | 2007 | Lupus2007,16,10: | 1 |
| 20 | Genome comparisons with chromosomal and molecular markers for three closely related Flax species and their hybrids显示文摘 | MURAVENKO V LEMESH V A SAMATADZE T E AMOSOVA A V GRUSHETSKAYA Z E POPOV K V YU O S KHOTYULEVA L V ZELENIN A V | 2003 | Russian Journal of Genetics2003,39,4: | 1 |