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| 1 | The biological stress of early weaned piglets显示文摘Pigs experience biological stress such as physiological, environmental, and social challenges when weaned from the sow. The process of weaning is one of the most stressful events in the pig's life that can contribute to intestinal and immune system dysfunctions that result in reduced pig health, growth, and feed intake, particularly during the first week after weaning. Technological improvements in housing, nutrition, health, and management have been used to minimize some of the adverse effects of weaning stress, but a greater understanding of the biological impact of stress is needed to improve strategies to overcome weaning stress. The focus of this review paper is to briefly describe how the biological stress associated with weaning impacts intestinal morphology, structure, physiology, and intestinal immune responses that can impact subsequent production efficiencies such as growth, intake, morbidity, and mortality. | Joy M Campbell Joe D Crenshaw Javier Polo | 2013 | Journal of Animal Science and Biotechnology2013，4，2： | 83 |
| 2 | 早期断奶仔猪的生物学应激显示文摘当仔猪断奶后离开其母猪时,会遭遇到生物学应激,如生理的、环境的和社会的挑战。断奶过程是猪一生中最具应激性的事件,会造成肠道和免疫系统的机能障碍,结果导致猪健康状况、生长性能和采食量的降低,特别是断奶后首周内。饲养系统、营养、健康和管理技术的改进已被用来将断奶应激的一些不利影响降至最小程度,但是更好地了解应激的生物学作用,为改进能够克服断奶应激的策略所需要的。本综述的重点,是简要地描述与断奶有关的生物学应激是如何通过影响肠道形态、结构、生理和肠道免疫反应,进而可能会影响生产效率,如生长、采食量、发病率和死亡率。 | 陈建康 Joy M Campbell Joe D Crenshaw Javier Polo | 2014 | 国外畜牧学(猪与禽)2014，0，S1： | 8 |
| 3 | Food groups, diet quality and colorectal cancer risk in the Basque Country显示文摘BACKGROUND The results obtained to date concerning food groups,diet quality and colorectal cancer(CRC)risk vary according to criteria used and the study populations.AIM To study the relationships between food groups,diet quality and CRC risk,in an adult population of the Basque Country(North of Spain).METHODS This observational study included 308 patients diagnosed with CRC and 308 ageand sex-matched subjects as controls.During recruitment,dietary,anthropometric,lifestyle,socioeconomic,demographic and health status information was collected.Adherence to the dietary recommendations was evaluated utilizing the Healthy Eating Index for the Spanish Diet and the MedDietScore.Conditional logistic regressions were used to evaluate the associations of food group intakes,diet quality scores,categorized in tertiles,with CRC risk.RESULTS The adjusted models for potential confounding factors showed a direct association between milk and dairy products consumption,in particular high-fat cheeses[odds ratio(OR)third tertile vs first tertile=1.87,95%confidence intervals(CI):1.11-3.16],and CRC risk.While the consumption of fiber-containing foods,especially whole grains(OR third tertile vs first tertile=0.62,95%CI:0.39-0.98),and fatty fish(OR third tertile vs first tertile=0.53,95%CI:0.27-0.99)was associated with a lower risk for CRC.Moreover,higher MD adherence was associated with a reduced CRC risk in adjusted models(OR third tertile vs first tertile=0.40,95%CI:0.20-0.80).CONCLUSION Direct associations were found for high-fat cheese,whereas an inverse relation was reported for fiber-containing foods and fatty fish,as well as adherence to a Mediterranean dietary pattern. | Iker Alegria-Lertxundi Carmelo Aguirre Luis Bujanda Francisco J Fernandez Francisco Polo JoseMªOrdovas MªCarmen Etxezarraga Inaki Zabalza Mikel Larzabal Isabel Portillo Marian M de Pancorbo Koldo Garcia-Etxebarria Ana MªRocandio Marta Arroyo-Izaga | 2020 | World Journal of Gastroenterology2020，26，28： | 3 |
| 4 | Bovine immunoglobulin protein isolates for the nutritional management of enteropathy显示文摘The gastrointestinal tract is responsible for a multitude of digestive and immune functions which depend upon the balanced interaction of the intestinal microbiota, diet, gut barrier function, and mucosal immune response. Disruptions in one or more of these factors can lead to intestinal disorders or enteropathies which are characterized by intestinal inflammation, increased gut permeability, and reduced capacity to absorb nutrients. Enteropathy is frequently associated with human immunodeficiency virus(HIV) infection, inflammatory bowel disease, autoimmune enteropathy, radiation enteritis, and irritable bowel syndrome(IBS), where pathologic changes in the intestinal tract lead to abdominal discomfort, bloating, abnormal bowel function(e.g., diarrhea, urgency, constipation and malabsorption). Unfortunately, effective therapies for the management ofenteropathy and restoring intestinal health are still not available. An accumulating body of preclinical studies has demonstrated that oral administration of plasmaor serum-derived protein concentrates containing high levels of immunoglobulins can improve weight, normalize gut barrier function, and reduce the severity of enteropathy in animal models. Recent studies in humans, using serum-derived bovine immunoglobulin/protein isolate, demonstrate that such protein preparations are safe and improve symptoms, nutritional status, and various biomarkers associated with enteropathy. Benefits have been shown in patients with HIV infection or diarrhea-predominant IBS. This review summarizes preclinical and clinical studies with plasma/serum protein concentrates and describes the effects on host nutrition, intestinal function, and markers of intestinal inflammation. It supports the concept that immunoglobulin-containing protein preparations may offer a new strategy for restoring functional homeostasis in the intestinal tract of patients with enteropathy. | Bryon W Petschow Anthony T Blikslager Eric M Weaver Joy M Campbell Javier Polo Audrey L Shaw Bruce P Burnett Gerald L Klein J Marc Rhoads | 2014 | World Journal of Gastroenterology2014，20，33： | 2 |
| 5 | Adsorption of benzotriazole on copper electrode surfaces in citric acid media 显示文摘 | Bastidas J M Pinilla P Polo J L | 2002 | Corrosion2002，58，11： | 1 |
| 6 | Learning in chemistry with virtual laboratories显示文摘 | Jimenez P M Pedrajas A P Polo J | 2003 | Journal of Chemieal Edueation2003，80，3： | 1 |
| 7 | Pulsed laser deposition of diamond from graphite targets显示文摘 | Cifre J Sanchez G | 1995 | Applied Physics Letters1995，67，4： | 1 |
| 8 | 显示文摘 | Polo M C Martinez E Esteve J | 1999 | Diamond Rel Mater1999，8，： | 1 |
| 9 | Proteolytic effect of Oenococcus oeni on the nitrogenous macromolecular fraction of red wine显示文摘 | DE NARDA M C M FARIAS M E POLO M C | 1999 | FEMS Microbiol Lett1999，174，1： | 1 |
| 10 | Buyer power and quality improvements显示文摘 | BATTIGALLI P FUMAGALLI C POLO M | 2007 | Research in Eco- nomics2007，61，2： | 1 |
| 11 | An in vivo model of human proliferative scar 显示文摘 | Polo M Kim YJ Kucukcelebi A | 1998 | J Surg Res1998，74，2： | 1 |
| 12 | Varietal differentiation of musts and wines by means of protein fraction显示文摘 | PUEYO E POLO M C DIZY M | 1993 | American Journal of Enology and Viticulture1993，44，： | 1 |
| 13 | 显示文摘 | SANCHEZ - POLO M RIVERA - UTRILLA J ZAROR C A | 2002 | J Chem Technol Biotechnol2002，77，： | 1 |
| 14 | When fibroblasts MET iPSCs显示文摘 | Polo J M Hochedlinger K | 2010 | Cell Stem Cell2010，7，1： | 1 |
| 15 | Visual DSD: a design and analysis tool for DNA strand dis- placement systems 显示文摘 | LAKIN M R YOUSSEF S POLO F | 2011 | Bioinformatics2011，27，22： | 1 |
| 16 | Virus-based vectors for human vaccine applications显示文摘 | Polo J M Dubensky T W | 2002 | Drug Discov Today2002，7，： | 1 |
| 17 | Development of a solid - phase microextraction gas chromatography/tandem mass spectrometry method for polybrominated diphenyl ethers and polybrominated biphenyls in water samples 显示文摘 | Polo M Gomez - Noya G Quintana JB | 2004 | Analy Chem2004，76，4： | 1 |
| 18 | Removal of pharmaceutical compounds,nitroimidazoles,from waters by using the ozone/carbon system显示文摘 | Sánchez Polo M Rivera Utrilla J Prados Joya G | 2008 | Water Res2008，42，15： | 1 |
| 19 | Botulinum toxin type A in the treatment of excessive gingival display 显示文摘 | Polo M | 2005 | Am J Orthod Dentofacial Orthop2005，127，： | 1 |
| 20 | Adsorption of benzotriazole on copper electrode surface in citric acide midia 显示文摘 | Bastidas J M Pinilla P Polo J L | 2002 | Corrosion2002，58，11： | 1 |
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