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| 1 | Device-associated infection rates, mortality, length of stay and bacterial resistance in intensive care units in Ecuador: International Nosocomial Infection Control Consortium's findings显示文摘AIM To report the results of the International Nosocomial Infection Control Consortium(INICC) study conducted in Quito, Ecuador.METHODS A device-associated healthcare-acquired infection(DAHAI) prospective surveillance study conducted from October 2013 to January 2015 in 2 adult intensive care units(ICUs) from 2 hospitals using the United States Centers for Disease Control/National Healthcare Safety Network(CDC/NHSN) definitions and INICC methods. RESULTS We followed 776 ICU patients for 4818 bed-days. The central line-associated bloodstream infection(CLABSI) rate was 6.5 per 1000 central line(CL)-days, the ventilator-associated pneumonia(VAP) rate was 44.3 per 1000 mechanical ventilator(MV)-days, and the catheterassociated urinary tract infection(CAUTI) rate was 5.7 per 1000 urinary catheter(UC)-days. CLABSI and CAUTI rates in our ICUs were similar to INICC rates [4.9(CLABSI) and 5.3(CAUTI)] and higher than NHSN rates [0.8(CLABSI) and 1.3(CAUTI)]- although device use ratios for CL and UC were higher than INICC and CDC/NSHN's ratios. By contrast, despite the VAP rate was higher than INICC(16.5) and NHSN's rates(1.1), MV DUR was lower in our ICUs. Resistance of A. baumannii to imipenem and meropenem was 75.0%, and of Pseudomonas aeruginosa to ciprofloxacin and piperacillin-tazobactam was higher than 72.7%, all them higher than CDC/NHSN rates. Excess length of stay was 7.4 d for patients with CLABSI, 4.8 for patients with VAP and 9.2 for patients CAUTI. Excess crude mortality in ICUs was 30.9% for CLABSI, 14.5% for VAP and 17.6% for CAUTI. CONCLUSION DA-HAI rates in our ICUs from Ecuador are higher than United States CDC/NSHN rates and similar to INICC international rates. | Estuardo Salgado Yepez Maria M Bovera Victor D Rosenthal Hugo A González Flores Leonardo Pazmino Francisco Valencia Nelly Alquinga Vanessa Ramirez Edgar Jara Miguel Lascano Veronica Delgado Cristian Cevallos Gasdali Santacruz Cristian Pelaéz Celso Zaruma Diego Barahona Pinto | 2017 | World Journal of Biological Chemistry2017，8，1： | 23 |
| 2 | High prevalence of vitamin A deficiency in Crohn's disease patients according to serum retinol levels and the relative dose-response test显示文摘AIM:To assess the vitamin A status of patients with Crohn's disease(CD) by evaluating serum retinol levels and the relative dose response(RDR) test(liver retinol stores).METHODS:Vitamin A nutritional status was measured by serum retinol obtained by high performance liquid chromatography and the RDR test for evaluation of the hepatic stores.Body composition was performed by densitometry by dual-energy X-ray absorptiometry.Vitamin A dietary intake was assessed from a semiquantitative food frequency questionnaire.RESULTS:This study included 38 CD patients and 33 controls.Low serum retinol concentrations were detected in 29% of CD patients vs 15% in controls(P < 0.005).The RDR test was positive in 37% of CD patients vs 12% in controls,which indicated inadequate hepatic vitamin A stores(P < 0.005).Individuals with hypovitaminosis A had lower BMI and body fat compared with those without this deficiency.There was no association between vitamin A deficiency and its dietary intake,ileal location,presence of disease activity and prior bowel resections.CONCLUSION:Patients with CD have higher prevalence of vitamin A deficiency,as assessed by two independent methods. | Márcia Soares-Mota Tianny A Silva Luanda M Gomes Marco AS Pinto Laura MC Mendon?a Maria Lúcia F Farias Tiago Nunes Andrea Ramalho Cyrla Zaltman | 2015 | World Journal of Gastroenterology2015，21，5： | 4 |
| 3 | Liver preservation prior to transplantation: Past, present, and future显示文摘Since Dr. Thomas Starzl performed the first series of successful liver transplants(LTs), important advances have been made in immunosuppression, operative techniques, and postoperative care. In 1988, Belzer's group reported the first successful LT using the University of Wisconsin preservation solution(UW).Since then, UW has replaced EuroCollins solution and allowed prolonged and safer preservation of liver, kidney, and pancreas allografts, thus contributing to the improvement of transplant outcomes. Although UW is still considered the standard of care in the United States and in several countries worldwide, a recent meta-analysis revealed similar LT outcomes among UW, Celsior solution, and the Institut Georges Lopez-1 preservation solution, which were slightly superior to those obtained with histidine-tryptophan-ketoglutarate preservation solution.Dynamic preservation has been recently developed, and liver allografts are preserved mainly through the following methods: hypothermic machine perfusion, normothermic machine perfusion, and subnormothermic machine perfusion. Their use has the potential advantage of improving clinical results in LT involving extended criteria donor allografts. Although associated with increased costs, techniques employing machine perfusion of liver allografts have been considered clinically feasible. This editorial focuses on recent advances and future perspectives in liver allograft preservation. | Marcio F Chedid Marcelo A Pinto Jose Felipe G Juchem Tomaz J M Grezzana-Filho Cleber R P Kruel | 2019 | World Journal of Gastrointestinal Surgery2019，11，3： | 4 |
| 4 | 改变进气门相位对进气充量的影响显示文摘活塞与进气门交互运动产生的压力波会沿整个进气管传播,这种压力波能适当增加进入发动机气缸的进气质量。进行了改变进气门相位的试验研究,目的是分析它对进气充量的影响。‘试验在一台1. O L,16气门、每缸?,个进气门的产品发动机上进行。先在气流试验台上进行模拟发动机进气流状况的初步试验,然后再在测功器上进行发动机试验。气流试验台测试结果显示,在300CaA范围内改变进气相位角能使进气质量增加。发动机台架试验的结果是在进气门比原来气门开启相位迟开7. 50CaA的情况下测得的。 | Pereira L V M Pires L B M Pinto A A 李慧萍 | 2005 | 国外内燃机2005，37，6： | 2 |
| 5 | 5-Hydroxy-2-(phenyl or styryl) chromones: one-pot synthesis and C-6, C-8 ^13C NMR assignments 显示文摘 | Silva A M S Pinto D C C A Cavaleiro J A S | 1994 | Tetrahedron Lett1994，35，32： | 1 |
| 6 | Hydrogen peroxide, nitric oxide and cytosolic ascorbate peroxidase at the crossroad between defence and cell death 显示文摘 | de Pinto M C Paradiso A Leonetti P | 2006 | Plant Journal2006，48，5： | 1 |
| 7 | In vitro activity of Brazilian medicinal plants,naturally occurring naphthoquinones and their analogues,against methicillin-resistant staphylococcus aureus显示文摘 | MACHADO T B PINTO A V PINTO M C | 2003 | Int J Antimicrob Ag2003，21，3： | 1 |
| 8 | A hydrogen Deroxide-inactivated virus vaccine elicits humoral and cellular immunity and protects against lethal West Nile virus infection in aged mice显示文摘 | PINTO A K RICHNER J M POORE E A | 2013 | Journal of virology2013，87，4： | 1 |
| 9 | Syntheses of 5-hydroxy-2-(phenyl or styryl)chromones and of some halo derivatives显示文摘 | Pinto D C G A Silva A M S Cavaleiro J A S | 1996 | J Heterocycl Chem1996，33，： | 1 |
| 10 | The chemistry of isatins:a review from 1975 to 1999显示文摘 | Silva J F M Garden S J Pinto A C | 2001 | Braz Chem Soc2001，12，： | 1 |
| 11 | Theoretical accuracy of synthetic aperture sonar micronavigation using displaced phase centre antenna 显示文摘 | BELLETTINI A PINTO M A | 2002 | IEEE Journal of Oceanic Engineering2002，27，： | 1 |
| 12 | Simple and rapid method determination for metformin in human plasma using high performance liquid chromatography tandem mass spectrometry: application to pharmacokinetic studies 显示文摘 | S'lpoli Marques M A Soares A S Pinto O W | 2007 | Chromatography B2007，852，： | 1 |
| 13 | To treat or not to treat? A meta-analysis of the use of cholinesterase inhibitors in mild cognitive impairment for delaying progression to Alzheimer's disease显示文摘 | Diniz B S Pinto J A Jr Gonzaga M L | 2009 | Eur Arch Psychiatry Clin Neurosci2009，259，： | 1 |
| 14 | Evolution of a method for quantitative supercritical fluid extraction of ethanox 330 antioxidant from high-density polyethylene显示文摘 | Pinto A M Taylor L | 1998 | J Chromatogr A1998，811，12： | 1 |
| 15 | Structural studies of the polysaccharide isolated from Spondias purpurea gum exudate显示文摘 | PINTO G L D MARTINEZ M MENDOZA J A | 1996 | Carbohydr Res1996，290，： | 1 |
| 16 | Pathogenicity of Bacillus thuringiensis isolated from two species of Acromyrmex (Hymenoptera,Formicidae)显示文摘 | PINTO L M AZAMBUJA A O DIEHL E | 2003 | Braz J Biol2003，63，2： | 1 |
| 17 | A comparison of DNA extraction methods for food analysis 显示文摘 | Pinto A I) Forte V T Guastadisegni M C | 2007 | Food Contr2007，18，： | 1 |
| 18 | Analysis of solid wood beams strengthened with CFRP laminates of distinct lengths显示文摘 | DE JESUS A M P PINTO J M T MORAIS J J L | 2012 | Construction and Building Materials2012，35，1： | 1 |
| 19 | Acute tracheohronehiaI injuries: impact of imaging on diagnosis and management implications显示文摘 | Scaglione M Romano S Pinto A | 2006 | Eur J Radiol2006，59，3： | 1 |
| 20 | Targeting the endothelin axis in prostate carcinoma显示文摘 | PINTO A MERINO M ZAMORA P | 2011 | TumourBiol2011，，： | 1 |
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