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| 1 | Intraoperative cell salvage with autologous transfusion in liver transplantation显示文摘Liver transplant(LT) is the primary treatment for patients with end-stage liver disease. About 25000 LTs are performed annually in the world. The potential for intraoperative bleeding is quite variable. However, massive bleeding is common and requires blood transfusion. Allogeneic blood transfusion has an immunosuppressive effect and an impact on recipient survival, in addition to the risk of transmission of viral infections and transfusion errors, among others.Techniques to prevent excessive bleeding or to use autologous blood have been proposed to minimize the negative effects of allogeneic blood transfusion.Intraoperative reinfusion of autologous blood is possible through previous selfdonation or blood collected during the operation. However, LT does not normally allow autologous transfusion by prior self-donation. Hence, using autologous blood collected intraoperatively is the most feasible option. The use of intraoperative blood salvage autotransfusion(IBSA) minimizes the perioperative use of allogeneic blood, preventing negative transfusion effects without negatively impacting other clinical outcomes. The use of IBSA in patients with cancer is still a matter of debate due to the theoretical risk of reinfusion of tumor cells. However, studies have demonstrated the safety of IBSA in several surgical procedures, including LT for hepatocellular carcinoma. Considering the literature available to date, we can state that IBSA should be routinely used in LT, both in patients with cancer and in patients with benign diseases. | Marcelo A Pinto Marcio F Chedid Leo Sekine Andre P Schmidt Rodrigo P Capra Carolina Prediger Jo?o E Prediger Tomaz JM Grezzana-Filho Cleber RP Kruel | 2019 | World Journal of Gastrointestinal Surgery2019，11，1： | 16 |
| 2 | Characterization of goat whey proteins and their bioactivity and toxicity assay显示文摘Goat whey is an industry-discarded dairy by-product that has interesting nutritional value and a nutrient composition with important functional potential,where proteins have a high biological value and play an important role in the organism’s physiology.Therefore,the aim of this study was to identify,quantify,concentrate and investigate the capacity of goat whey proteins to perform different biological activities and to evaluate their acute toxicity.Concentrated proteins were quantified and identified by Bradford,Kjehdal and SDS-PAGE methods.Antibacterial activity was performed against Listeria monocytogenes,Salmonella spp.,Staphylococcus aureus,Pseudomonas aeruginosa and Escherichia coli microorganisms and showed MIC ranging from 15 to 120μg mL-1,with the highest inhibition for L.monocytogenes growth.Antiproliferative activity was performed against human malignant melanoma cells and their proliferation inhibition was up to 66.8%within 72 h of exposure.The highest antioxidant capacity was obtained at concentration 2 mg that showed 29.69%of inhibition of DPPH radical oxidation.The acute toxicity test was performed using Artemia franciscana larvae in which whey proteins were able to preserve larval survival throughout exposure.Thus,we can conclude that goat’s whey has proteins that can play a positive effect on health,with antimicrobial activity and without toxicity.The present study highlights the great potential of goat’s whey to be developed as a safe biopreservative or as a functional ingredient in the food industry. | Maria Isabel Ferreira Campos Paula Perazzo de Souza Barbosa Laura Junqueira Camargo Luciano Da Silva Pinto Bianca Mataribu Catarina Serr˜ao Luis Fernando Marques-Santos Jos´e Hon´orio Lopes Julia Mariano Caju de Oliveira Carlos Alberto de Almeida Gadelha Tatiane Santi-Gadelha | 2022 | Food Bioscience2022，46，2： | 2 |
| 3 | Spiral computed tomography in the assessment of vascular lesions of the pelvis due to blunt trauma显示文摘 | Pinto A De Lutio Di Castelguidone E | 2000 | Radiol Med ( Torino)2000，100，12： | 1 |
| 4 | Tricuspid annular motion显示文摘 | Hammarstrom E Wranne B Pinto FJ | 1991 | J Am Soc Echocardiogr1991，4，： | 1 |
| 5 | Double-blind, randomized, placebo-controlled Phase I Clinical Trial of the therapeutical anti-tuberculous vaccine RUTI 显示文摘 | Vilaplana C Montan6 E Pinto S | 2010 | Vaccine2010，28，4： | 1 |
| 6 | Cellular distributionof growth hormone-releasing hormone receptor in humanreproductive system and breast and prostate cancers显示文摘 | Gallego R Pintos E Garcia-Caballero T | 2005 | HistolHistopathoi2005，20，3： | 1 |
| 7 | A hydrogen Deroxide-inactivated virus vaccine elicits humoral and cellular immunity and protects against lethal West Nile virus infection in aged mice显示文摘 | PINTO A K RICHNER J M POORE E A | 2013 | Journal of virology2013，87，4： | 1 |
| 8 | Preoperative positivity of serum tumor markers in a stron predictor of hem atogenous recurrence of gastric cancer显示文摘 | Marrelli D Pinto E De Stefano A | 2001 | J Surg Oncol2001，78，4： | 1 |
| 9 | Pathogenicity of Bacillus thuringiensis isolated from two species of Acromyrmex (Hymenoptera,Formicidae)显示文摘 | PINTO L M AZAMBUJA A O DIEHL E | 2003 | Braz J Biol2003，63，2： | 1 |
| 10 | Trastuzumabfor patients with HER2 positive breast cancer: delivery,duration and combination therapies显示文摘 | Pinto AC Ades F de Azambuja E ef af | 2013 | Breast2013，，2： | 1 |
| 11 | Assignments and sequencing models for the scheduling of process systems 显示文摘 | PINTO J M GROSSMANN I E | 1998 | Annals of Operations Research1998，81，： | 1 |
| 12 | Functional and molecular characterization of tachykinins and tachykinin receptors in the mouse uterus显示文摘 | Patak E Pinto FM Story ME | 2005 | Biol Reprod2005，72，5： | 1 |
| 13 | Picomolar analysis of proteins using electrophoretically mediated microanalysis and capillary eleetrophoresis with laser-induced fluorescence detection显示文摘 | LEE I H PINTO D ARRIAGA E A | 1998 | Anal Chem1998，70，21： | 1 |
| 14 | Yield and composition of the essential oil of Ocimum selloi Benlh cultivated under colored netting显示文摘 | Costa L C B Pinto J E B P Castro E M | 2010 | Journal of Essential Oil Research2010，22，1： | 1 |
| 15 | Soil surface potentials induced by ITAIPU HVDC ground return current part i-theoretical evaluation显示文摘 | Kovarsky K Pinto L J Caroli C E | 1988 | IEEE Transactions on Power Delivery1988，3，3： | 1 |
| 16 | Reconstruc- tion of soft tissue defects of the heel with local faseiocutaneous flaps 显示文摘 | Benito - Ruiz J Yoon T Guisantes - Pintos E | 2008 | Ann Plasl Surg2008，52，： | 1 |
| 17 | Simulation for optimi- zing grain pattern on engineered grinding tools 显示文摘 | F W Pinto G E Vargas K Wegener | 2008 | CIRP Annals - Manufacturing Technology2008，57，： | 1 |
| 18 | Identification and typing of food-borne Staphylococcus aureusby PCR-based techniques显示文摘 | Pinto B Chenoll E Aznar R | 2005 | Systematic and Applied Microbiology2005，28，4： | 1 |
| 19 | Global health ethics for students 显示文摘 | Pinto A D Upshur R E | 2009 | Developing World Bioethics2009，9，1： | 1 |
| 20 | Synchronous collision malignant melanoma and adenocarcinoma of the rectum显示文摘 | Dias AR Pinto RA Mory E | 2010 | Tech Coloproctol2010，14，2： | 1 |
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