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| 1 | Transcriptome reprogramming,epigenetic modifications and alternative splicing orchestrate the tomato root response to the beneficial fungus Trichoderma harzianum显示文摘Beneficial interactions of rhizosphere microorganisms are widely exploited for plant biofertilization and mitigation of biotic and abiotic constraints.To provide new insights into the onset of the roots–beneficial microorganisms interplay,we characterised the transcriptomes expressed in tomato roots at 24,48 and 72 h post inoculation with the beneficial fungus Trichoderma harzianum T22 and analysed the epigenetic and post-trascriptional regulation mechanisms.We detected 1243 tomato transcripts that were differentially expressed between Trichoderma-interacting and control roots and 83 T.harzianum transcripts that were differentially expressed between the three experimental time points.Interaction with Trichoderma triggered a transcriptional response mainly ascribable to signal recognition and transduction,stress response,transcriptional regulation and transport.In tomato roots,salicylic acid,and not jasmonate,appears to have a prominent role in orchestrating the interplay with this beneficial strain.Differential regulation of many nutrient transporter genes indicated a strong effect on plant nutrition processes,which,together with the possible modifications in root architecture triggered by ethylene/indole-3-acetic acid signalling at 72 h post inoculation may concur to the well-described growth-promotion ability of this strain.Alongside,T.harzianum-induced defence priming and stress tolerance may be mediated by the induction of reactive oxygen species,detoxification and defence genes.A deeper insight into gene expression and regulation control provided first evidences for the involvement of cytosine methylation and alternative splicing mechanisms in the plant–Trichoderma interaction.A model is proposed that integrates the plant transcriptomic responses in the roots,where interaction between the plant and beneficial rhizosphere microorganisms occurs. | Monica De Palma Maria Salzano Clizia Villano Riccardo Aversano Matteo Lorito Michelina Ruocco Teresa Docimo Anna Lisa Piccinelli Nunzio D’Agostino Marina Tucci | 2019 | Horticulture Research2019，6，1： | 2 |
| 2 | Neuropsychological and behavioural aspects in children and adolescents with idiopathicepilepsy at diagnosis and after 12 months of treatment显示文摘 | Piccinelli P Beghi E Borgatti R | 2010 | Seizure2010，19，9： | 1 |
| 3 | 查看详情显示文摘 | Speghini A Piccinelli F Bettinelli M | | 0，，3： | 1 |
| 4 | Holmium laser enucleation of the prostate combined with mechanical morcellation in 155 patients with benign prostatic hyperplasia显示文摘 | Rodolfo Hurle Ivano Vavassori Alessandro Piccinelli Alberto Manzetti Sergio Valenti Alberto Vismara | 2002 | Urology2002，，3： | 1 |
| 5 | Percutaneous nephro- lithotomy:tubeless or not tubeless 显示文摘 | Giusti G Piccinelli A Maugeri O etal | 2009 | Urol Res2009，37，： | 1 |
| 6 | Gender differences in depression 显示文摘 | Piccinelli M Wilkinson G | 2000 | Br J Psychiatry2000，177，： | 1 |
| 7 | Upconversion luminescence in nanocrystals of Gd3Ga5O12 and Y3Al5O12 doped with Tb3+-Yb3+and Eu3+-Yb3+显示文摘 | ROGRIGUEZ R VALIENTE R POLIZZI S BETTINELLI M SPEGHINI A PICCINELLI F | | 0，，28： | 1 |
| 8 | New Lignans from the Roots of Valeriana prionophylla with Antioxidative andVasorolaxant Activities 显示文摘 | Anna Lisa Piccinelli Swizly Arana Armando Caceres | 2004 | Nat Prod2004，67，： | 1 |
| 9 | NIR-to-NIR Two-Photon Excited CaF2: Tm^3+ , Yb^3+ Nanoparticles: Multifunctional Nanoprobes for Highly Penetrating Fluorescence Bio-Imaging 显示文摘 | Dong N N Pedroni M Piccinelli F | 2011 | ACS Nano2011，5，11： | 1 |
| 10 | Macular thickness measured by optical coherence tomograpby in a healthy population before and after uncomplicated cataract phacoemulsification surgery显示文摘 | Cagini C Fiore T Iaccheri B Piccinelli F Ricci MA Fruttini D | 2009 | Current Eye Resereh2009，34，12： | 1 |
| 11 | An international study of the relation between somatic symptoms and depression显示文摘 | Simon GE Von Korff M Piccinelli M et aI | 1999 | N Engl J Med1999，541，18： | 1 |
| 12 | Chromatin organization during mouse oocyte growth显示文摘 | Zuccotti M Piccinelli A Rossi P G | 1995 | Mol Re- prod Dev1995，41，4： | 1 |
| 13 | Multimodality image fusion for diagnosing coronary artery disease显示文摘Coronary artery disease(CAD)is one of the leading causes of death in the US and a substantial health-care burden in all industrialized societies.In recent years we have witnessed a constant strive towards the development and the clinical application of novel or improved detection methods as well as therapies.Particularly,noninvasive imaging is a decisive component in the cardiovascular field.Image fusion is the ability of combining into a single integrated display the anatomical as well as the physiological data retrieved by separated modalities.Clinical evidence suggests that it represents a promising strategy in CAD assessment and risk stratification by significantly improving the diagnostic power of each modality independently considered and of the traditional side-by-side interpretation.Numerous techniques and approaches taken from the image registration field have been implemented and validated in the context of CAD assessment and management.Although its diagnostic power is widely accepted,additional technical developments are still needed to become a routinely used clinical tool. | Marina Piccinelli Ernest Garcia | 2013 | The Journal of Biomedical Research2013，27，6： | 1 |
| 14 | Percutaneous nephrolithotomy: tubeless or not tubeless? 显示文摘 | Giusti G Piccinelli A Maugeri O | 2009 | Urol Res2009，37，3： | 1 |
| 15 | Holmium laser enucleation of the prostate combined with mechanical morcellation in 155patients with binign prostatic hyperplasia显示文摘 | Hurle R Vavassori I Piccinelli A | | 0，，03： | 1 |
| 16 | Factors affecting formation and rupture of intracranial saccular aneurysms 显示文摘 | Bacigaluppi S Piccinelli M Antiga L | 2014 | Neurosurg Rev2014，37，1： | 1 |
| 17 | Structural and optical properties of vernier phase lutetium oxyfluorides doped with lanthanide ions:interesting candidates as scintillators and X-ray phosphors显示文摘 | Passuello T Piccinelli Trevisani M | 2012 | J Mater Chem2012，22，10： | 1 |
| 18 | White light upconversion of nanocrystalline Er/Tm/Yb doped tetragonal Gd 4 O 3 F 6显示文摘 | T. Passuello F. Piccinelli M. Pedroni M. Bettinelli F. Mangiarini R. Naccache F. Vetrone J.A. Capobianco A. Speghini | 2010 | Optical Materials2010，，4： | 1 |
| 19 | Gender differences in depression 显示文摘 | Piccinelli M Wilkinson G | 2000 | Br J Psychiatry2000，177，： | 1 |
| 20 | NIR-to-NIR two-photon excited CaF2:Tm3+,Yb3 + nanoparticles:Multifunctional nanoprobes for highly penetrating fluorescence bio-imaging显示文摘 | Dong N N Pedroni M Piccinelli F | | 0，，11： | 1 |
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