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34篇 您的检索式：作者名="PETER CS"

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	题名	作者	年代	出处	被引量
1	ATG16L1 and NOD2 polymorphisms enhance phagocytosis in monocytes of Crohn's disease patients显示文摘AIM:To investigate if the presence of relevant genetic polymorphisms has effect on the effectual clearance of bacteria by monocytes and granulocytes in patients with Crohn’s disease(CD).METHODS:In this study,we assessed the differential responses in phagocytosis by measuring the phagocytic activity and the percentage of active phagocytic monocytes and granulocytes in inflammatory bowel disease patients as well as healthy controls.As both autophagy related like 1(ATG16L1)and immunityrelated guanosine triphosphatase gene are autophagy genes associated with CD and more recently nucleo-tide-binding ligomerization domain-containing protein2(NOD2)has been identified as a potent inducer of autophagy we genotyped the patients for these variants and correlated this to the phagocytic reaction.The genotyping was done with restriction fragment length polymorphisms analysis and the phagocytosis was determined with the pHrodo?Escherichia coli Bioparticles Phagocytosis kit for flowcytometry.RESULTS:In this study,we demonstrate that analysis of the monocyte and granulocyte populations of patients with CD and ulcerative colitis showed a comparable phagocytic activity(ratio of mean fluorescence intensity)between the patient groups and the healthy controls.CD patients show a significantly higher phagocytic capacity(ratio mean percentage of phagocytic cells)compared to healthy controls(51.91%±2.85%vs 37.67%±7.06%,P=0.05).The extend of disease was not of influence.However,variants of ATG16L1(WT:2.03±0.19 vs homozygoot variant:4.38±0.37,P<0.009)as well as NOD2(C-ins)(heterozygous variant:42.08±2.94 vs homozygous variant:75.58±4.34(P=0.05)are associated with the phagocytic activity in patients with CD.CONCLUSION:Monocytes of CD patients show enhanced phagocytosis associated with the presence of ATG16L1 and NOD2 variants.This could be part of the pathophysiological mechanism resulting in the disease.	Simone CS Wolfkamp Caroline Verseyden Esther WM Vogels Sander Meisner Kirsten Boonstra Charlotte P Peters Pieter CF Stokkers Anje A te Velde	2014	World Journal of Gastroenterology2014，20，10：	2
2	Renal blood flow changes induced with endothelin and fenoldopam messy-late at quantitative doppler US:initial results in a canine study显示文摘	Chandra MS Peter HA Anthony CS	2001	Radiology2001，219，2：	1
3	Molecular characterization of intrahepatic and extrahepatic hepatitis B virus (HBV) reservoirs in patients on suppressive antiviral therapy显示文摘	Coffin CS Mulrooney-Cousins PM Peters MG	2011	J Viral Hepat2011，18，6：	1
4	Connective tissue growth factor in retrocorneal membranes and corneal scars 显示文摘	Kerstin W Brigitte CS Peter R ct al	2000	Ophthalmologica2000，214，5：	1
5	Uhrastructural characteristics of sin nombre virus, causative agent of hantavirus pulmonary syndrome显示文摘	Goldsmith CS Elliott LH Peters C J		0，，：	1
6	Inhibitors of human histone deacetylase:synthesis and enzyme and cellular activity of straight chain hydroxamates显示文摘	Stacy WR Lidia CS Peter A	2002	J Med Chem2002，45，4：	1
7	Buckley Naturalistic studies of second generation antipsychotics in the treatment of schizophrenia显示文摘	Sebastian CS Glazer W Peter F	2004	Current Med Chemistry2004，11，：	1
8	New insights into TGFβ-Smad signaling显示文摘	Peter ten D Hill CS	2004	Trend Biochem Sci2004，29，5：	1
9	Management of congenital nonpigmented iris cyst显示文摘	Christopher CS Peter AN Matthew WW	2006	Ophthalmology2006，113，：	1
10	Ibuprofen versus acetaminophen with codeine for the relief of perineal pain after childbirth: a randomized controlled trial显示文摘	Peter EA Janssen PA Grange CS	2001	Canad Med Assoc Licen2001，165，9：	1
11	Effects of Raf kinase inhibitor protein expression on suppression of prostate cancer metastasis显示文摘	Fu Z Peter CS Zhang LZ Rubin MA Dunn RL Yao Z	2003	J Natl Cancer Inst2003，95，12：	1
12	Association of plasminogen activator inhibitor-1 4G/4G genotype and type 2 diabetic nephropathy in Chinese patients显示文摘	Teresa YHW Peter P Cheuk CS	2000	Kidney International2000，57，：	1
13	The epidemiology of nonfatal injuries among US children and youth显示文摘	PETER CS YOSSI H ANN CT	1995	Am J Public Health1995，85，：	1
14	Nipah virus: a recently emergent deadly paramyxovirus 显示文摘	Chua KB Bellini WJ Rota PA Harcourt BH Tamin A Lam SK Ksiazek TG RoUin PE Zaki SR Shieh W Goldsmith CS Gubler DJ Roehrig JT Eaton B Gould AR Olson J Field H Daniels P Ling AE Peters CA Anderson IJ Mahy BW	2000	Science2000，288，5470：	1
15	ATF-7,a novel bZIP protein,interacts with the PRL-1 protein-tyrosine phosphatase 显示文摘	Peters CS Liang X Li S	2001	J Biol Chem2001，276，13：	1
16	Prevalence of and risk factors for depressive symptoms among young adolescents 显示文摘	Gitanjali S Ronaldo I Peter CS	2004	Arch Pediatr Adolesc Med2004，158，：	1
17	Asolid-state dye sensitizedso-lar cells显示文摘	Fei C Gerko O Peter CS	1995	J Phys Chem1995，99，17：	1
18	Nathanielsz lipoxygenase gene expression in baboon intrauterine tissues in late pregnancy and partu- rition显示文摘	Gordon CS Smith Wen X Wu Peter W	2001	Mol Hum Reprod2001，7，6：	1
19	Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes显示文摘	Karly CS Brooke EH Peter HT		0，，03：	1
20	Identification of a rough strain of Escehricha coli O157:H7 that prouductes no detectable O157 antigen显示文摘	Peter F Robin CS Choong HP	1998	J Clin Microbiol1998，36，8：	1

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