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| 1 | 高胆固醇血症诱导血管生成并加速活体内乳腺肿瘤的生长显示文摘肥胖和代谢综合征可增加绝经后妇女乳腺癌的患病率。肥胖、代谢综合征和西方富于饱和脂肪酸的饮食习惯,这三者共同的特征是高水平的胆固醇循环。流行病学报道关于高水平的胆固醇循环、降胆固醇药物与乳腺癌之间的关系仍有争议,因此我们通过控制饮食和等热量饮食建立临床前动物模型模拟这一复杂状况。通过低脂肪/无胆固醇饮食喂养雌性SCID裸鼠,然后随机分成4组等热量饮食组:低脂肪/无胆固醇组(使用和不使用依替米贝两组)(依替米贝是一种降胆固醇药物)、高脂肪/高胆固醇组(使用和不使用依替米贝两组)。然后裸鼠被原位植入MDA-MB-231细胞。 | Pelton K Coticchia C M Curatolo A S 魏建国 许春伟 | 2014 | 临床与实验病理学杂志2014,30,10: | 11 |
| 2 | Rates and risk factors for suicidal ideation,suicide attempts and suicide deaths in persons with HIV:a systematic review and meta-analysis显示文摘Background People living with HIV/AIDS(PLWHA)must contend with a significant burden of disease.However,current studies of this demographic have yielded wide variations in the incidence of suicidality(defined as suicidal ideation,suicide attempt and suicide deaths).Aims This systematic review and meta-analysis aimed to assess the lifetime incidence and prevalence of suicidality in PLWHA.Methods Publications were identified from PubMed(MEDLINE),SCOPUS,OVID(MEDLINE),Joanna Briggs Institute EBP and Cochrane Library databases(from inception to before 1 February 2020).The search strategy included a combination of Medical Subject Headings associated with suicide and HIV.Researchers independently screened records,extracted outcome measures and assessed study quality.Data were pooled using a random-effects model.Subgroup and meta-regression analyses were conducted to explore the associated risk factors and to identify the sources of heterogeneity.Main outcomes were lifetime incidence of suicide completion and lifetime incidence and prevalence of suicidal ideation and suicide attempt.Results A total of 185199 PLWHA were identified from 40 studies(12 cohorts,27 cross-sectional and 1 nested case-control).The overall incidence of suicide completion in PLWHA was 10.2/1000 persons(95%CI:4.5 to 23.1),translating to 100-fold higher suicide deaths than the global general population rate of 0.11/1000 persons.The lifetime prevalence of suicide attempts was 158.3/1000 persons(95%CI:106.9 to 228.2)and of suicidal ideation was 228.3/1000 persons(95%CI:150.8 to 330.1).Meta-regression revealed that for every 10-percentage point increase in the proportion of people living with HIV with advanced disease(AIDS),the risk of suicide completion increased by 34 per 1000 persons.The quality of evidence by Grading of Recommendations,Assessment,Development and Evaluations for the suicide deaths was graded as‘moderate’quality.Conclusions The risk of suicide death is 100-fold higher in people living with HIV than in the general population.Lifetime incidence of suicidal ideation and attempts are substantially high.Suicide risk assessments should be a priority in PLWHA,especially for those with more advanced disease. | Matt Pelton Matt Ciarletta Holly Wisnousky Nicholas Lazzara Monica Manglani Djibril M Ba Vernon M Chinchillli Ping Du Anna E Ssentongo Paddy Ssentongo | 2021 | General Psychiatry2021,34,2: | 3 |
| 3 | A thermodynamic database for copper smelting and converting显示文摘 | Sergei A. Degterov Arthur D. Pelton | 1999 | Metallurgical and Materials Transactions B1999,,4: | 3 |
| 4 | Photocatalytic paper from colloidal TiO 2 —fact or fantasy显示文摘 | Robert Pelton Xinglian Geng Michael Brook | 2006 | Advances in Colloid and Interface Science2006,,1: | 2 |
| 5 | Temperature-sensitive aqueous microgels 显示文摘 | Pelton R | 2000 | Adva Collo interf Sci2000,85,: | 1 |
| 6 | A double-blind, placebocontrolled study of risperidone addition in serotonin reuptake inhibitorrefractory obsessive-compulsive disorder 显示文摘 | McDougle CJ Epperson CN Pelton GH | 2000 | Arch Gen Psychiatry2000,57,: | 1 |
| 7 | TGF beta inhibits branching morphogenesis andN myc expression in lung bud organ cultures 显示文摘 | Serra R Pelton RW | 1994 | Development1994,120,: | 1 |
| 8 | 显示文摘 | Shen Y Q Zhu S P Zheng F Q Pelton R | 2000 | Macromolecules2000,33,: | 1 |
| 9 | Energy Balance, Metabolic Status, and the First Postpartum Ovarian Follicle Wave in Cows Administered Propylene Glycol显示文摘 | S.T. Butler S.H. Pelton W.R. Butler | 2006 | Journal of Dairy Science2006,,8: | 1 |
| 10 | Mineral discrimination and removal of inductive coupling with multrfrequency IP 显示文摘 | Pelton W H Ward S H Hallof P G | 1978 | Geophysics1978,43,3: | 1 |
| 11 | Hypercholesterolemia promotes an osteoporotic phenotype显示文摘 | Pelton K Krieder J Joiner D | 2012 | Am J Pathol2012,181,: | 1 |
| 12 | Coupled thermodynamicphase diagram assessment of the rare earth oxide-aluminum oxide binary systems显示文摘 | WU Ping PELTON A D | 1992 | Journal of Alloys and Compounds1992,179,12: | 1 |
| 13 | Mineral Discrimination and Removal of Inductive Coupling with Multifrequency IP显示文摘 | Pelton W H Ward S H | 1978 | Geophysics1978,43,3: | 1 |
| 14 | Characterization of the strength and microstructure of heavily cold worked Cu-Nb composites显示文摘 | Spitzig W A Pelton A R Laabs F C | 1987 | Acta Metall1987,35,10: | 1 |
| 15 | Some properties of newsprint impregnated with polyvinylamine显示文摘 | Pelton R Hong J | 2002 | Tappi Journal2002,1,10: | 1 |
| 16 | Preparation and kinetic characterization of copolymers of AM and PEO acrylate mactomonomers 显示文摘 | Xiao H Pelton R Hamielec A | 1996 | Polymer1996,37,7: | 1 |
| 17 | Prevention of invasive meningococcal disease in the United States 显示文摘 | Pelton SI | 2009 | Pediatr Infect Dis J2009,28,4: | 1 |
| 18 | Mineral discrimination and removal of inductive coupling with multifrequency IP显示文摘 | PELTON W.H WARD S.H HALLOF P.G | | 0,,43: | 1 |
| 19 | 显示文摘 | Pelton A Stockel D | 1999 | Mater Sci Eng A1999,273,275: | 1 |
| 20 | Optimization of three-dimensional micro post microcavities for cavity quantum eletrodynamics显示文摘 | VUCKOVIC J PELTON M SCHERER A | 2002 | Phys Rev A2002,66,02: | 1 |