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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Importance of pre-ionisation for the non chain discharge pumped HF laser显示文摘 | Lacour B Pasquiers S Postel C | 2001 | Appl Phys B2001，72，3： | 1 |
| 3 | Surgical pathology of drug-resistent partial epilepsy:a 10-year experience with a series of327 consecutive resections显示文摘 | Pasquier B Peoch HM Fabre-Bocquentin B | 2002 | Epileptic Disorder2002，4，： | 1 |
| 4 | Chordoid glioma of the third ventricle:a report of two new cases,with further evidence supporting an ependymal differentiation,and review of the literature显示文摘 | Pasquier B Peoch M Morrison AL | 2002 | Am J Surg Pathot2002，26，10： | 1 |
| 5 | Surgical pathology of drug-resistent partial epilepsy:a10-year experience with a series of 327 consecutiveresections显示文摘 | Pasquier B Peoc' h M Fabre-Bocquentin B | 2002 | Epileptic Disorder2002，4，： | 1 |
| 6 | Premature ovarian failure显示文摘 | Christin-Maitre S Pasquier M Donadille B | 2006 | Ann Endocrinol:Paris2006，67，6： | 1 |
| 7 | Chordoid glioma of the third ventricle: a report of two new cases, with further evidence supporting an ependymal differentiation, and re- view of the literature 显示文摘 | Pasquier B Peoc' h M Morrison AL | 2002 | Am J Surg Pathol2002，26，10： | 1 |
| 8 | Antiangiogenic activity of paclitaxel is associated with its cytostatic effect, mediated by the initiation but not completion of a mitochondrial apoptotic signaling pathway 显示文摘 | Pasquier E Carré M Pourroy B | 2004 | Mol Cancer Ther2004，3，10： | 1 |
| 9 | Platform-to-basin correlation by high-resolution sequence stratigraphy and cyclostratigraphy (Berriasian,Switzerland and France)显示文摘 | Pasquier J B Strasser A | 1997 | Sedimentology1997，44，6： | 1 |
| 10 | Thymolipona association with myasthemia gravis显示文摘 | Le Marchadour F Pine N Pasquier B | 1991 | Am J Surg Pathol1991，15，： | 1 |
| 11 | Novel LiNi1/3Co1/3Mn1/3O2 cathode morphologies for high power Li-ion batteries显示文摘 | Oljaca M Blizanac B Pasquier A D | 2014 | Journal of Power Sources2014，248，15： | 1 |
| 12 | Surgical pathology of drug-resistaat partial epilepsy: a lO-yearexperience with a series of 327 consecutive resections显示文摘 | PASQUIER B PEOCH M FABRE-BOCQUENTIN B | 2002 | Epilep-tic Disorder2002，4，： | 1 |
| 13 | Atypical Presentations of Solitary Fibrous Tumors of the Central Nervous System:an Analysis of Unusual Clinicopathological and Outcome Pat terns in Three New Cases with a Review of the Literature显示文摘 | Pakasa NM Pasquier B Chambonniere ML | 2005 | Virchows Arch2005，447，2： | 1 |
| 14 | Synthesis of novel diarylpyrimidine analogues of TMC278 and their antiviral activity against HIV-1 wild-type and mutant strains 显示文摘 | Mordant C Schmitt B Pasquier E | 2007 | Eur J Med Chem2007，42，： | 1 |
| 15 | Importance of pre-ionisation for the non-chain discharge-pumped HF laser显示文摘 | Lacour B Pasquiers S Postel C | 2001 | Appl Phys B2001，72，3： | 1 |
| 16 | Atypical presentations of solitary fibrous tumors of the central nervous system: an analysis of unusual clinicopathologieal and outcome patterns in three new eases with a review of the literature 显示文摘 | Pakasa NM Pasquier B Chambonnie're ML | 2005 | Virchows Arch2005，447，： | 1 |
| 17 | Atypicalpresentations of solitary fibrous tumors of the central nervous system :an analysis of unusual clinicopathological and outcome patterns inthree new cases with a review of the literature 显示文摘 | Pakasa NM Pasquier B Chambonnifere ML | 2005 | Virchows Arch2005，447，1： | 1 |
| 18 | An experimental investigation of flame propagation through a turbulent stratified mixture显示文摘 | Pasquier N Lecordier B Trinite M | 2007 | Proceedings of the Combustion Insti- tute2007，31，1： | 1 |
| 19 | Injectable percutaneous bonematerials : An experimental study in a rabbit model显示文摘 | Pasquier G Flautre B Blary MC | 1996 | J Mater Sci Mater Med1996，7，： | 1 |
| 20 | Thymolipoma in association with myasthenia gravis显示文摘 | Pinel N Pasquier B | 1991 | Am J Surg Pathol1991，15，8： | 1 |
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