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| 1 | Microstructure,mechanical response and fractography of AZ91E/Al_(2)O_(3)_(p) nano composite fabricated by semi solid stir casting method显示文摘The present study confers to the fabrication and its characterization of magnesium alloy(AZ91E)based nano composites with nano Al_(2)O_(3) particulate reinforcements.A novel Semi Solid stir casting technique was adopted for the fabrication of the composite.An average particle size of 50 nm was used as reinforcement to disperse in matrix.The effects of change in weight fraction of reinforcements on the distribution of particles,particle–matrix interfacial reactions,physical as well as mechanical properties were reported.The SEM and EDS analysis has shown the uniform distribution of particles in the composite along with the presence of elements.The mechanical properties of reinforced and unreinforced composite were evaluated and presented.Fractography of tensile specimens was also discussed. | Sameer Kumar D Suman K.N.S Tara Sasanka C Ravindra K Palash Poddar | 2017 | Journal of Magnesium and Alloys2017，5，1： | 4 |
| 2 | Critical role of OX40 signaling in the TCR-independent phase of human and murine thymic Treg generation显示文摘Regulatory T cells(Tregs)play a pivotal role in immune-tolerance,and loss of Treg function can lead to the development of autoimmunity.Natural Tregs generated in the thymus substantially contribute to the Treg pool in the periphery,where they suppress self-reactive effector T cells(Teff)responses.Recently,we showed that OX40L(TNFSF4)is able to drive selective proliferation of peripheral Tregs independent of canonical antigen presentation(CAP-independent)in the presence of low-dose IL-2.Therefore,we hypothesized that OX40 signaling might be integral to the TCR-independent phase of murine and human thymic Treg(tTreg)development.Development of tTregs is a two-step process:Strong T-cell receptor(TCR)signals in combination with co-signals from the TNFRSF members facilitate tTreg precursor selection,followed by a TCR-independent phase of tTreg development in which their maturation is driven by IL-2.Therefore,we investigated whether OX40 signaling could also play a critical role in the TCR-independent phase of tTreg development.OX40−/−mice had significantly reduced numbers of CD25−Foxp3low tTreg precursors and CD25+Foxp3+mature tTregs,while OX40L treatment of WT mice induced significant proliferation of these cell subsets.Relative to tTeff cells,OX40 was expressed at higher levels in both murine and human tTreg precursors and mature tTregs.In ex vivo cultures,OX40L increased tTreg maturation and induced CAP-independent proliferation of both murine and human tTregs,which was mediated through the activation of AKT-mTOR signaling.These novel findings show an evolutionarily conserved role for OX40 signaling in tTreg development and proliferation,and might enable the development of novel strategies to increase Tregs and suppress autoimmunity. | Prabhakaran Kumar Alejandra Marinelarena Divya Raghunathan Vandhana K Ragothaman Shikha Saini Palash Bhattacharya Jilao Fan Alan L Epstein Ajay V Maker Bellur S Prabhakar | 2019 | Cellular & Molecular Immunology2019，16，2： | 4 |
| 3 | Processing and mechanical properties of SiC reinforced cast magnesium matrix composites by stir casting process显示文摘 | Palash Poddar Srivastava V C De P K | 2007 | Materials Science artd Engineering: A2007，，： | 1 |
| 4 | Processing and mechanical properties of SiC reinforced east magnesium matrix composites by stir casting process显示文摘 | PALASH P SRIVASTAVA V C DE P K | 2007 | Materials Science and Engineering A2007，，1： | 1 |
| 5 | Prevalence of iron- deficiency anaemia among university students in Noakhali Region, Bangladesh 显示文摘 | KUMAR B S PALASH K KIBRIA M G | 2014 | J Health Popul Nutr2014，32，1： | 1 |
| 6 | Miscibility of PVDF/ PMMA blends examined by crystallization dynamics显示文摘 | Hozumi S Palash K B Hirohisa Y | 1995 | Polymer1995，36，25： | 1 |
| 7 | Evolving utility of exosomes in pancreatic cancer management显示文摘Despite the development of newer oncological treatment,the survival of patients with pancreatic cancer(PC)remains poor.Recent studies have identified exosomes as essential mediators of intercellular communications and play a vital role in tumor initiation,metastasis and chemoresistance.Thus,the utility of liquid biopsies using exosomes in PC management can be used for early detection,diagnosis,monitoring as well as drug delivery vehicles for cancer therapy.This review summarizes the function,and clinical applications of exosomes in cancers as minimally invasive liquid biomarker in diagnostic,prognostic and therapeutic roles. | Thattungal Manoharan Anoop Palash Kumar Basu K Chandramohan Ajai Thomas S Manoj | 2023 | World Journal of Methodology2023，13，3： | 0 |
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