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| 1 | 局灶节段透明变性及硬化在判断IgA肾病预后中的意义显示文摘目的 探讨IgA肾病 (IgAN)进展为慢性肾功能不全 (CRI)的病理学危险因素。方法 对 6 40例经肾活检确诊的IgAN病人进行平均 5 3个月的追踪观察。用病例对照法研究所有病人的病理学资料 ,同时还对其中 2 0 4例活检当时肾功能正常 ,5年后发展为CRI或终末期肾功能衰竭(ESRF) (n =18)以及 5年后肾功能仍保持正常 (n =186 )的病例进行了比较。结果 弥漫性系膜增生型 (DMP)为最常见的病理型 ,占 5 0 %。 / 间质纤维化 ,>40 %硬化肾小球 , / 血管病变 ,局灶节段透明变性及硬化 (FSHS)的均为预测肾功能恶化的危险因素 ,其中FSHS的意义更大 (P <0 0 0 0 1)。结论 FSHS的存在是IgAN病人正常肾功能进展恶化的显著指标。 | 严海东 Packham D Kincaid Smith P Becker G 周希静 | 1999 | 中华肾脏病杂志1999，15，5： | 20 |
| 2 | 血小板功能测定显示文摘1 简介
血小板在止血和血栓中的作用
当血管损伤时,血小板会迅速粘附到损伤处,聚集形成由纤维蛋白固定的止血块.在微血管损伤处及破裂的动脉粥样硬化斑块处也会发生类似的过程,最终形成血小板-纤维蛋白血栓,引发动脉硬化症的血栓性并发症. | Rand ML Leung R Packham MA 金蕾 | 2004 | 国外医学(输血及血液学分册)2004，27，4： | 3 |
| 3 | Domiciliary nocturnal intermittent p o sitive pressure ventilation in patients with respiratory failure due to severe C OPD:long term follow up and effect on survival显示文摘 | Jones S E Packham S Hebden M | 1998 | Thorax1998，53，： | 2 |
| 4 | Long-term follow up of 246 adults with juvenile idiopathic arthritis:Functional outcome显示文摘 | Packham JC Hall MA | | 0，，12： | 1 |
| 5 | T-box genes in human disorders显示文摘 | Packham E A Brook J D | 2003 | Hum Mol Genet2003，12，1： | 1 |
| 6 | Transrectal biopsy of the prostate and bacteraemia显示文摘 | Thompson PM Talbot RW Packham DA | 1980 | Br J Surg1980，67，： | 1 |
| 7 | Effects of ethanol on pathways of platelet aggregation in vitro 显示文摘 | Rand ML Packham MA Kinlough-Rathbone RL | 1988 | Thromb Haemost1988，59，3： | 1 |
| 8 | Regulation of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Burkittps lymphoma cell lines显示文摘 | Mouzakiti A Packham G | 2003 | Br J Haematol2003，122，1： | 1 |
| 9 | Unmet health needs in patients with coronary heart disease: Implications and potential for improvement in caring services显示文摘 | Asadi - Lari M Packham C Gray D | 2003 | Health Qual Life Outcomes2003，23，1： | 1 |
| 10 | Selective regulation of Bel-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies显示文摘 | Packham G White EL Eisehen CM | 1998 | Genes Dev1998，12，16： | 1 |
| 11 | Some Studies of the Coagulation of Dispersed Clays with Hydrolyzed Salts显示文摘 | | 1995 | Coll Inter Sci1995，20，： | 1 |
| 12 | 显示文摘 | Digby R P Packham D E | 1995 | Int J Adhes & Adhes1995，15，2： | 1 |
| 13 | Renal biopsy:indications and complications in pregnancy显示文摘 | Packham D Fairley KF | | 0，，10： | 1 |
| 14 | Ertapenem-associated psychosis andencephalopathy显示文摘 | Oo Y Packham D Yau W | 2014 | Intern Med J2014，44，8： | 1 |
| 15 | Chelating polymers derived from polyvinyl alcohol and cellulose显示文摘 | Gibson G K J packham P I | 1966 | J Appl Chem1966，16，： | 1 |
| 16 | A20 RNA expression is associated with undifferentiated nasopharyngcel carcinoma and poorly differentiated head and neck squamous cell carcinoma 显示文摘 | CODD J D SALISBURY J R PACKHAM G | 1999 | J Pathol1999，187，5： | 1 |
| 17 | Relative incidence of ESRD versus cardiovascular mortality in proteinuric type 2 diabetes and nephropathy: results from the DIAMETRIC (Diabetes Mellitus Treatment for Renal Insufficiency Consortium) database 显示文摘 | Packham DK Alves TP Dwyer JP | 2012 | Am J Kidney Dis2012，59，1： | 1 |
| 18 | Macrolactamization versus macrolactonization: total synthesis of FK228, the depsipeptide histone deacetylase inhibitor 显示文摘 | WEN S J PACKHAM G H GANESAN A | 2008 | J Org Chem2008，73，23： | 1 |
| 19 | T-box genes in human disorders显示文摘 | Packham EA Brook J D | 2003 | Hum Mol Genet2003，12，1： | 1 |
| 20 | Harmonisation between main contractors and subcontractors: aprerequisite for lean construction 显示文摘 | MILLER CJM PACKHAM GA THOMAS BC | 2002 | Journal of Constructian Research2002，3，1： | 1 |
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