| 1 | A Dynamic and Quantitative Study of Pattern Visual Evoked Potentials and Gamma-Aminobutyric Acid Neurones in the Lateral Geniculate Nucleus and the Visual Cortex of Monocular Deprivation Cats显示文摘Purpose: To assess the effects of monocular lid closure during critical period on cortical activity.Method: Pattern visual evoked potentials (PVEP) of the normal and the monocular deprivation (MD) cats were dynamically measured and the number of gam-maaminobutyric acid immunopositive (GABA-IP) neurones of the area 17 of the visual cortex and the lateral geniculate nucleus (LGN) was quantitatively compared by using immunohistochemical method (ABC).Result: The amplitude of the N1-P1 attenuated in deprived eyes (DE) , NE/DE at postnatal week (PNW) 7-8 (P<0. 05), NE/DE at PNW 15-16 (P<0. 01); while P1 latency delayed, NE/DE at PNW 7-8 (P>0. 05), NE/DE at PNW 15 - 16(P<0. 05). The numbers of GABA-IP neurones in layer A1 of the ipsilateral LGN and in layer A of the contralateral LGN, compared to those in the corresponding normal laminae, were not significant at PNW 7 - 8 and PNW 11 - 12 (P >0. 05), while in the same cats a reduction in the number of GABA-IP neurcnes was found in layer IV of area 17 at PNW | Hong Yan, Donggao Zhang, Xingguang Yang, Dan Ma, Qide JiaDepartment of Ophthalmology, Tangdu Hospital, The Fourth Military Medical University P.L.A. Institute of Neuroscience, Xian, 710038, China | 1996 | Eye Science1996，16，3： | 2 |
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