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| 1 | The aryl hydrocarbon receptor: a regulator of Th17 and Treg cell development in disease显示文摘 | Peggy P Ho Lawrence Steinma | 2008 | Cell Research2008，18，6： | 11 |
| 2 | Mammary gland growth and vascularity at parturition and during lactation in primiparous ewes fed differing levels of selenium and nutritional plane during gestation显示文摘Background: Objectives were to examine the effects of selenium(Se) supply and maternal nutritional plane during gestation on mammary gland growth, cellular proliferation, and vascularity at parturition and d 20 of lactation. Rambouillet primiparous ewes(n = 84) were allocated to treatments in a 2 x 3 factorial. Factors were dietary Se(adequate Se [ASe, 11.5 μg/kg BW] or high Se [HSe, 77.0 μg/kg BW]) and nutritional plane(60% [RES], 100% [CON], or 140% [EXC]). At parturition, lambs were removed and 42 ewes(7/treatment) were necropsied. Remaining ewes were fed a common diet meeting requirements for lactation and mechanically milked twice daily until necropsy on d 20. At both necropsy periods, mammary glands were dissected and tissues harvested. Samples were analyzed for RNA, DNA, and protein content, cell proliferation, and vascularity. Where interactions were present(P ≤ 0.05), least squares means from the highest-order interaction are presented. Results: Final body weight of ewes was least(P ≤ 0.002) in RES, intermediate for CON, and greatest for EXC, regardless of stage of the ewe at necropsy(parturition or d 20 of lactation). In ewes necropsied at parturition, mammary glands were heavier(P = 0.02) in EXC compared to RES, with CON intermediate. Concentration of RNA(mg/g) was decreased(P = 0.01) in EXC compared to CON at parturition. There was a tendency(P = 0.07) for a Se by nutrition interaction in percentage of cells proliferating where ASe-EXC ewes had greater(P ≤ 0.02) number of proliferating cells then all other treatments. Mammary vascular area tended(P = 0.08) to be affected by a Se by nutrition interaction where ASe-CON had less(P = 0.007) vascular area than HSe-CON ewes. In ewes necropsied at d 20 of lactation, the number of alveoli per area was decreased(P ≤ 0.05) in RES compared to CON and EXC-fed ewes. Conclusions: Results of this study indicate that proper maternal nutritional plane during gestation is important for mammary gland development, even out to d 20 of lactation. | Tammi L Neville Allison M Meyer Arshi Reyaz Pawel B Borowicz Dale A Redmer Lawrence P Reynolds Joel S Caton Kimberly A Vonnahme | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 3 |
| 3 | Volumetric Analysis Predicts Hepatic Dysfunction in Patients Undergoing Major Liver Resection显示文摘 | Margo Shoup Mithat Gonen Michael D’Angelica William R Jarnagin Ronald P DeMatteo Lawrence H Schwartz Scott Tuorto Leslie H Blumgart Yuman Fong | 2003 | Journal of Gastrointestinal Surgery2003，，3： | 2 |
| 4 | Yttrium-90 microsphere selective internal radiation therapy for liver metastases following systemic chemotherapy and surgical resection for metastatic adrenocortical carcinoma显示文摘Adrenocortical carcinoma(ACC)is a rare malignancy with generally poor outcomes and limited treatment options.While surgical resection can be curative for early local disease,most patients present with advanced ACC owing to nonspecific symptoms.For those patients,treatment options include systemic chemotherapy and locoregional therapies including radiofrequency ablation and transarterial chemoembolization.We present the first reported case of utilizing yttrium-90 microsphere selective internal radiation therapy(SIRT)in combination with first line EDP-M(Etoposide,Doxorubicin,Cisplatin,Mitotane)chemotherapy and debulking surgical primary tumor resection for treatment of metastatic ACC.Stable complete radiologic response has been maintained after twelve months with resolution of clinical symptoms.These findings prompt the need for further consideration and studies to elucidate the role of SIRT in combination with systemic and surgical treatment for metastatic ACC. | Mina S Makary Lawrence S Krishner Evan J Wuthrick Mark P Bloomston Joshua D Dowell | 2018 | World Journal of Clinical Oncology2018，9，1： | 2 |
| 5 | Identification of inertial and friction parameters for excavator arms 显示文摘 | Tafazoli S Lawrence P D Salcudean S E | 1999 | IEEE Transactions on Robotics and Automation1999，15，5： | 1 |
| 6 | Repeat sequence proteins as matrices for nanocomposites显示文摘 | Lawrence F D Hilmar K David M P | 2009 | Mater Sci Eng2009，29，： | 1 |
| 7 | Immunolocalization of type III collagen in human articular cartilage prepared by high- pressure eryofixation, freeze-substitution, and low-temperature embedding显示文摘 | Young R D Lawrence P A Duanee V C | 1995 | J Histochem Cytochem1995，43，4： | 1 |
| 8 | Yeast re- sponses to stresses associated with industrial brewery han- dling 显示文摘 | Gibson B R Lawrence S J Leclaire J P R | 2007 | FEMS Microbiology Reviews2007，31，5： | 1 |
| 9 | Can J Zool显示文摘 | Lawrence P Akin D | 1990 | 68:539-5461990，68，： | 1 |
| 10 | Aluminm alloy 2519 in military vehicles显示文摘 | James J F Lawrence S K Joseph R P | 2002 | Advanced Materials and Processes2002，160，9： | 1 |
| 11 | Aluminum alloy 2519 in military vehicles显示文摘 | James J F Lawrence S K Joseph R P | 2002 | Advanced Materials and Processes2002，160，9： | 1 |
| 12 | Direct protein interaction underlies gene-for-gene specificity and coevolution of the flax resistance genes and flax rust avirulence genes显示文摘 | Dodds P N Lawrence G J Catanzariti A M | 2006 | Proc Natl Acad Sci USA2006，103，： | 1 |
| 13 | The development of a tool to assess neonatal pain显示文摘 | Lawrence J Alcock D McGrath P | 1993 | Neonatal Netw1993，12，6： | 1 |
| 14 | Review of genes and linkage groups in cucumber显示文摘 | Lawrence K P Wehner T C | 1990 | HortScience1990，25，6： | 1 |
| 15 | A model specification for FRP composites for civil engineering structures显示文摘 | Lawrence C Bank T.Russell Gentry Benjamin P Thompson Jeffrey S Russell | 2003 | Construction and Building Materials2003，，6： | 1 |
| 16 | Beyond Vertical Integration :The Rise of the Value-added Partnership显示文摘 | R Johnston & P Lawrence | 1988 | Harvard Business Review1988，66，4： | 1 |
| 17 | The Melampsora lini AvrL567 avirulence genes are expressed in haustoria and their products are recognized inside plant cells 显示文摘 | Dodds P N Lawrence G J Catanzariti A M | 2004 | The Plant Cell2004，16，： | 1 |
| 18 | Organization and environment 显示文摘 | Lawrence P R Lorsch J | 1967 | Division of Research1967，，： | 1 |
| 19 | A quantitative analysis of digestive enzymes in penaeid shrimp: influences of diet, age and species显示文摘 | Lee P G Lawrence A L | 1982 | Physiologist1982，25，： | 1 |
| 20 | ,Quality Function Deployment显示文摘 | | 1988 | Quality Progress1988，，6： | 1 |
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