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| 1 | Feasibility of progressive strength training shortly after hip fracture surgery显示文摘AIM: To investigate the feasibility of a 6-wk progressive strength-training programme commenced shortly after hip fracture surgery in community-dwelling patients.METHODS: This prospective, single-blinded cohort study evaluated 31 community-dwelling patients from four outpatient geriatric health centres aged 60 years or older, who started a 6-wk programme at a mean of 17.5 ± 5.7 d after hip fracture surgery. The intervention consisted primarily of progressive fractured kneeextension and bilateral leg press strength training(twice weekly), with relative loads commencing at 15 and increasing to 10 repetitions maximum(RM), with three sets in each session. The main measurements included progression in weight loads, hip fracture-related pain during training, maximal isometric knee-extension strength, new mobility score, the timed up and go test, the 6-min walk test and the 10-meter fast speed walk test, assessed before and after the programme.RESULTS: Weight loads in kilograms in the fractured limb knee-extension strength training increased from 3.3 ± 1.5 to 5.7 ± 1.7 and from 6.8 ± 2.4 to 7.7 ± 2.6, respectively, in the first and last 2 wk(P < 0.001). Correspondingly, the weight loads increased from 50.3 ± 1.9 to 90.8 ± 40 kg and from 108.9 ± 47.7 to 121.9 ± 54 kg in the bilateral leg press exercise(P < 0.001). Hip fracture-related pain was reduced, and large improvements were observed in the functional outcome measurements, e.g., the 6-min walk test improved from 200.6 ± 79.5 to 322.8 ± 68.5 m(P < 0.001). The fractured limb knee-extension strength deficit was reduced from 40% to 17%, compared with the non-fractured limb. Ten patients reported knee pain as a minor restricting factor during the last 10 RM knee-extension strength-training sessions, but with no significant influences on performance. CONCLUSION: Progressive strength training, initiated shortly after hip fracture surgery, seems feasible and does not increase hip fracture-related pain. Progressive strength training resulted in improvement, although a strength deficit of 17% persisted in the fractured limb compared with the non-fractured limb. | Jan Overgaard Morten T Kristensen | 2013 | World Journal of Orthopedics2013，4，4： | 9 |
| 2 | Lead levels of Culex mosquito larvae inhabiting lead utilizing factory显示文摘Objective:To determine lead level primarily in Culex quinquefasciatus(Cx.quinquefasciatus), and Culex gelidus(Cx.gelidus) larvae inhabiting lead consuming factories,and to putatively estimate eco-toxicological impact of effluents from the firms.Methods:Third instars larvae were sampled by standard dipping method and lead concentrations in the larvae and their respective surrounding factory aquatic environments were determined through standard atomic absorption spectrophotometry(AAS).Results:Cx.quinquefasciatus was the most abundant species followed by Cx.gelidus.The levels of lead were higher in the Cx.quinquefasciatus(1.08-47.47μg/g),than in the wastewaters surface(0.01-0.78 μg/mL) from the factories or closer areas around factories. Other species were not reaching the.criteria for lead determination.Conclusions:The Cx. quinquefasciatus larvae can bio-accumulate the metal and can potentially serve as a biomarker of lead contamination,to complemente conventional techniques. | Kitvatanachai S Apiwathnasorn C Leemingsawat S Wongwit W Overgaard HJ | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，1： | 6 |
| 3 | Pregnancy-associated plasma protein-A (PAPP-A) in ovine,bovine,porcine,and equine ovarian follicles:involvement in IGF binding protein-4 proteolytic degradation and mRNA expression during follicular development显示文摘 | Overgaard MT Oxvig C | 2001 | Endocrinology2001，142，： | 1 |
| 4 | Protective effects of lactic acid on force production in rat skeletal muscle显示文摘 | Nielsen O B de Paoli F Overgaard K | 2001 | J Physiol2001，536，1： | 1 |
| 5 | Body metal concentrations and glycogen reserves in earthworms (Dendrobaena octaedra) from contaminated and uncontaminated forest soil 显示文摘 | Holmstrup M Sorensen J G Overgaard J | 2011 | Environmental Pollution2011，159，1： | 1 |
| 6 | Effects of citicoline combined with thrombolytic therapy in a rat embolic stroke model 显示文摘 | Anderson M Overgaard K Meden P | 1999 | Stroke1999，30，7： | 1 |
| 7 | Pregnancy-associated plasma protein A as a marker of acute coronary syndromes显示文摘 | Bayes-GenisA Conover CA Overgaard MT | 2001 | N Engl J Med2001，345，： | 1 |
| 8 | Expression of recombi- nant human pregnancy - associated plasma protein - A and identifica- tion of the proform of eosinophil major basic protein as its physiologi- ca] inhibitor显示文摘 | Overgaard MT Haaning J Boldt HB | | J Biol Chem0，275，31： | 1 |
| 9 | Pregnancy associated plasma protein A as a marker of acute coronary syndromes显示文摘 | Bayes-Gents A Conover CA Overgaard MT | | 0，，： | 1 |
| 10 | Definition, expression, and characterization of a protein domain in the N-terminus of pregnancy-associated plasma protein-A distantly related to the family of laminin G-like modules 显示文摘 | Boldt HB Glerup S Overgaard MT | 2006 | Protein Expr Purif2006，48，2： | 1 |
| 11 | Pregnancy associated plasma protein A as a marker of acute coronary syndromes显示文摘 | BAYES-GENIS A CONOVER CA OVERGAARD MT | 2001 | N Engl J Med2001，345，14： | 1 |
| 12 | Participation of mitogen-activated protein kinase in luteinizing hormoneinduced differential regulation of steroidogenesis and steroidogenic gene expression in mural and cumulus granulosa cells of mouse preovulatory follicles显示文摘 | Su Y Q Nyegaard M Overgaard M T | 2006 | Biology of Reproduction2006，75，6： | 1 |
| 13 | Pregnancy-associated plasma protein A as a marker of acute coronary syndromes 显示文摘 | Bayes-Genis A Conover CA Overgaard MT | 2001 | N Engl J Med2001，345，14： | 1 |
| 14 | Risk factors of ann lymphedema in breast cancer patlents显示文摘 | Kocak Z Overgaard J | 2000 | Acta Oncol2000，39，3： | 1 |
| 15 | Neuurprotection by excitatory amino acid antagonist augments the benefit of thrombolysis in embolic stroke in rats显示文摘 | Sereghy T Overgaard K Boysen G | 1993 | Stroke1993，24，11： | 1 |
| 16 | Coronary vasospasm: a case report and review of the literature显示文摘 | Van Spall H G Overgaard C B Abramson B L | 2005 | Can J Cardiol2005，21，11： | 1 |
| 17 | Pregnancy-associated plasma protein A as a marker of acute coronary syndromes显示文摘 | Bayes-C enis A Conover C A Overgaard M T | 2001 | N Engl J Med2001，345，14： | 1 |
| 18 | Molecular regulation of the IGF-binding protein4 protease system in human fibroblastsidentification of a novel inducible inhibitor显示文摘 | Chen BK Overgaard MT Bale LK | 2002 | Endocrinology2002，143，： | 1 |
| 19 | Messengerribonucleic acid levels of pregnancy-associated plasmaprotein-A and the profrom of eosinophil major basis protein:expression in human reproductive and nonreproductivetissues显示文摘 | Overgaard MT Oxvig C Christianses M | 1999 | Biol Reprod1999，61，4： | 1 |
| 20 | Participation of mitogen- activated protein kinase in luteinizing hormone-induced differential regulation of steroidogenesis and steroidogenic gene expression in mural and cumulus granulosa cells of mouse preovulatory follicles 显示文摘 | Su YQ Nyegaard M Overgaard MT | 2006 | Biol Reprod2006，75，6： | 1 |
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