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| 1 | Adjuvant chemotherapy for resected colorectal cancermetastases:literature review and meta-analysis显示文摘Surgical resection is the only option of cure for patients with metastatic colorectal cancer(CRC). However, the risk of recurrence within 18 mo after metastasectomy is around 75% and the liver is the most frequent site of relapse. The current international guidelines recommend an adjuvant therapy after surgical resection of CRC metastases despite the lower level of evidence(based on the quality of studies in this setting). However, there is still no standard treatment and the effective role of an adjuvant therapy remains controversial. The aim of this review is to report the state-of-art of systemic chemotherapy and regional chemotherapy with hepatic arterial infusion in the management of patients after resection of metastases from CRC, with a literature review and meta-analysis of the relevant randomized controlled trials. | Giovanni Brandi Stefania De Lorenzo Margherita Nannini Stefania Curti Marta Ottone Filippo Gustavo Dall’Olio Maria Aurelia Barbera Maria Abbondanza Pantaleo Guido Biasco | 2016 | World Journal of Gastroenterology2016，22，2： | 13 |
| 2 | The reduction of Cr(Ⅵ) by iron(Ⅱ) aqueous solution显示文摘 | Pettine M Ottone D L Campanella L | 1998 | Geochimica et Cosmohimica Acta1998，62，9： | 2 |
| 3 | Mergers and Shareholder Wealth in European Banking显示文摘 | Cyho - Ottone A Murgia M | 2000 | Journal of Banking & Finance2000，，24： | 1 |
| 4 | Molecular clo?ning v overexpression in Escherichia coli, and purification of 6-his-tagged C-terminal domain of Clostridium difficile toxins A and B显示文摘 | Letourneur 0 Ottone S Delauzun V | 2003 | Protein Expr Purif2003，31，2： | 1 |
| 5 | Diabetes induces apoptosis in lymphocytes显示文摘 | Otton R Soriano FG Verlengia R | 2004 | J Endocrinol2004，182，1： | 1 |
| 6 | Ultralong and Mesoporous ZnO and γ-Al_2O_3 Oriented Nanowires Obtained by Template-assisted Hydrothermal Approach显示文摘Highly mesoporous Zn O and g-Al2O3nanowires(NWs) are both synthesized by a hydrothermal method using commercially available porous anodic aluminium oxide(AAO) as template. AAO membrane acts as template for Zn O NWs and both as template and precursor for g-Al2O3 NWs. The formation of intermediate phases of porous Zn6Al2(OH)16CO3and boehmite(g-Al OOH) were observed, both occurring during the hydrothermal synthesis of porous Zn O and g-Al2O3 NWs, respectively, and disappearing after annealing at 600 C. This novel template-assisted hydrothermal process leads to the formation of porous Zn O and g-Al2O3NWs(specific surface area of 192 m2 g 1and 263 m2 g 1, respectively), showing pore sizes around 4 nm in diameter. The influence of the reaction parameters on the nanostructure morphology was also investigated. A Zn O seed layer, deposited on the AAO channels prior to the hydrothermal synthesis, leads to more compact Zn O nanowires(99 m2 g-1) protecting the AAO host from the chemical attack of the precursor solution. | Carminna Ottone Vivian Farías Rivera Marco Fontana Katarzyna Bejtka Barbara Onida Valentina Cauda | 2014 | Journal of Materials Science & Technology2014，30，12： | 1 |
| 7 | Use of quinidine in hihition to define the role of the sparteine/debrisoquine cyto- chrome P450 in metoprolol oxidation by human liver microsomes 显示文摘 | Otton SV Crewe HK Lennard MS | 1988 | JPharmaeolExpTher1988，247，1： | 1 |
| 8 | Diabetes induces apoptosis in lymphocytes 显示文摘 | Otton R Soriano FG Verlengia R | 2004 | J Endocrinol2004，182，1： | 1 |
| 9 | Oxidative stress in human lympho- cytes treated with fatty acid mixture: role of carotenoid astaxanthin 显示文摘 | Campoio TR Oliveira FA Otton R | 2011 | Toxicol In Vitro2011，25，7： | 1 |
| 10 | Risk of acute promyelocytic leukemia in multiple sclerosis: coding variants of DNA repair genes 显示文摘 | Hasan SK Buttari F Ottone T | 2011 | Neurology2011，76，： | 1 |
| 11 | Investigation of the Formation of Poly(ethylene terephthalate)with Model Molecules显示文摘 | Ratton Serge Vasnev Valerii A | 1988 | Journal of Polymer Science Part A:Polymer Chemistry1988，26，12： | 1 |
| 12 | Expression of hepatitis B surface antigen major subtypes in Pichia pastoris and purification for in vitro diagnosis显示文摘 | Ottone S Nguyen X Bazin J | 2007 | Protein Expr Purlf2007，86，2： | 1 |
| 13 | Diabetes induces apoptosis in lymphoeytes显示文摘 | Otton R Soriano FG Verlengia R | 2004 | J Endocrino12004，182，1： | 1 |
| 14 | A low carbon, low TEWI refrigeration system designs显示文摘 | Thomas W Davies Ottone Caretta | 2004 | Applied Thermal Engineering2004，24，2： | 1 |
| 15 | MRMaid,the web-based tool for designing multiple reaction monitoring(MRM) transitions显示文摘 | Mead JA Bianco L Ottone V | | 0，，04： | 1 |
| 16 | Hemodynamec alterations associated with epidural anesthesia显示文摘 | MCLEAN A P H MULLIGAN G W OTTON P | 1967 | Surgery1967，62，： | 1 |
| 17 | Mergers and shareholder wealth in European banking显示文摘 | Cybo - Ottone A M Murgia | 2000 | Journal of Banking and Finance2000，24，6： | 1 |
| 18 | Modelling of anaerobic digestion in a fluidized bed with a view to control 显示文摘 | Beteau J F Otton V Hihn J Y | 2005 | Bio- chem Eng J2005，24，3： | 1 |
| 19 | Constructing membership function u- sing interpolation and measurement theory 显示文摘 | CHEN J E OTTON | 1995 | Fuzzy sets and system1995，，73： | 1 |
| 20 | Estrogen receptor polymorphisms and the risk of endometrial cancer显示文摘 | Ashton KA Proietto A Otton G | | 0，，： | 1 |
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