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| 1 | 镍钛形状记忆合金细胞相容性和生物力学兼容性的改进显示文摘镍钛记忆合金(NiTi)生物材料器件的发展,迫切要求研究和提高其细胞相容性和生物力学性能。依据美国材料测试标准协会(ASTM)的标准,我们研究表明:NiTi的细胞毒性比纯钛、Ti6A14V和316L不锈钢大,在NiTi表面作聚合四氟乙烯高离子(PPTFE)喷涂。可降低NiTi合金的细胞毒性,提高其抗腐蚀力。各种热处理方法可改善其疲劳性能,循环拉伸强度试验可测出其超弹性性能的衰减。 | L’H Yahia S.Lombardi N.Hagemeister G.Drouin C.H. Rivard M .Assad Okuyaman(Biomechanical-Biomaterials Research Group, Biomedical Engineering Institute, Ecole Polytechnique de Montreal,Canada)(Department of Orthopaedic Surgery,Hospital St.Justine, Montreal, | 1995 | 医用生物力学1995，10，2： | 9 |
| 2 | 中国骨科生物力学的未来显示文摘在阐述生物力学和生物工程定义和范畴、回顾生物力学的近代发展史基础上,对中国骨科生物力学今后的研究方向、发展目标及其前景作了预测。作者认为,要在医疗卫生事业上取得重要突破,需要生命科学家和工程师的精诚合作。因此,随着医疗卫生事业的进步,生物医学工程的发展前景将比以往更为灿烂。 | Edmund Y. S. Chao, Ph. D.(Orthopaedic Research, Johns Hopkins University, Baltimore, Maryland, USA) | 1995 | 医用生物力学1995，10，1： | 2 |
| 3 | Preparation of acellular nerve grafts with triton X-100显示文摘BACKGROUND: The source of nerve allograft enriches.We may choose expediently nerve allograft to repair injured nerve and the structure of choice nerve homlolgy or similar with the injured nerve,but the immunological rejiction limits the climical application of nerve allograft.The ideal substitute of autograft never is reaearching.OBJECTIVE: In this experiment,Triton X-100 was used to extract the Schwann cells and myelin sheaths of allograft nerve and obtain the inartiflcial and eliminated antigenicity nerve-transplanter(nerve grafts).DESIGN: Controlled experiment.SETTING: Department of Hand Surgery,the Third Affiliated Hospital of Hebei Medical University;Second Department of Orthopedics,Fourth Center Hospital of Tianjin.MATERIALS: Thirty heath New Zealand big ear white rabbit .of either sex(gender).weighing 2000-3000 g,were provided by the Center of Experimental Animal of Hebei Medical University.Triton X-100 was offered by SIGMA Company.METHODS: The experiment was carried out at the Central Laboratory of the Third Affiliated Hospital of Hebei Medical University from December 2003 to December 2004.Sixty pieces of sciatic nerves.10-mm-long nerve segment,which were taken from 30 rabbits,were incised.They were randomly divided into chemical extraction group(n=50)and control group(n=10).In the chemical extraction groups,the nerves were put into 3% Triton X-100 solution.They were treated with Triton X-100 for 12 hours,24 hours,48 hours,96 hours and 1 week.respectively.They were examined in every period.The control groups did not treated with anything. ①Respectively two segments of nerve by 2 mm length were taken from each nerve in the every periods.②The laminin immunohistochemical stained sections were performed with image acquisition and analyzed with multicolor pathological image analysis system.Measured the laminin antibody reaction part of each section and computed laminin average gray degrees of the unit area.All dates were analyzed by SPSS 10.0 software.MAIN OUTCOME MEASURES:①General observation and histological observation in two groups;②Compared with laminin average gray degrees of the unit area in each section.RESULTS:①General observation:In the control groups,fresh nerve was polish,rigidity and elasticity.After the nerves were chemical extracted,the floccules was seen at two ends and around of the nerves.The nerves being extraction presented ivory and lackluster. Its diameter and length compared reduced,tenderness and tenacity with the fresh nerve.0bserved by light microscope,Schwann cells,myelin sheaths and basement membrane distribute uniformly in control groups.After the nerves were extracted,Schwann cells and myelin sheaths disappeared. Basement membrane presented barrier array in longitudinal sections. Between the membranes was the basement membrane tube.Observed with scanning electron microscope,the basement membrane tubes composed by collagen fibers were remained and collagen fibers maintained their former position,form and structure.Further,the structure of membrane was seen in the tubes.It was Schwann cells basement membrane.②In chemical extraction groups,laminin average gray degrees of the unit area were 140.1±3.41(12 hours),142.1±3.14(24 hours),142.1±3.14(48 hours),140.4±4.03(96 hours),141.7±2.62(1 week).In the control groups,laminin average gray degree of the unit area was 142.7±7.24.There were not significant differences among the groups (P>0.05).CONCLUSION:The method of chemical extraction by using of Triton X-100 may be an ideal measure for preparing tissue-engineered nerve-transplanter and reserved the live of laminin in the basement membrane. | Jinbao Han1, Juwen Chen2, Baohui Zhao1, Jichun Zhang1, Dehu Tian1, Jiuhui Han1 1Department of Hand Surgery, the Third Affiliated Hospital, Hebei Medical University, Shijiazhuang 050051, Hebei Province, China 2Second Department of Orthopaedics, the Fourth Center Hospital of Tianjin, Tianjin 300140, China | 2006 | Neural Regeneration Research2006，1，7： | 2 |
| 4 | Guidelines for management of pediatric acute hyperextension spinal cord injury显示文摘Pediatric acute hyperextension spinal cord injury(SCI)named as PAHSCI by us,is a special type of thoracolumbar SCI without radiographic abnormality and highly related to back-bend in dance training,which has been increasingly reported.At present,it has become the leading cause of SCI in children,and brings a heavy social and economic burden.Both domestic and foreign academic institutions and dance education organizations lack a correct understanding of PAHSCI and relevant standards,specifications or guidelines.In order to provide standardized guidance,the expert team formulated this guideline based on the principles of science and practicability,starting from the diagnosis,differential diagnosis,etiology,admission evaluation,treatment,complications and prevention.This guideline puts forward 23 recommendations for 14 related issues. | Lian Zeng Yu-Long Wang Xian-Tao Shen Zhi-Cheng Zhang Gui-Xiong Huang Jamal Alshorman Tracy Boakye Serebour Charles H.Tator Tian-Sheng Sun Ying-Ze Zhang Xiao-Dong Guo on behalf of Chinese Orthopaedic Association,Spinal Cord Injury and Rehabilitation Group,Chinese Association of Rehabilitation Medicine,Group of Spinal Injury and Functional Reconstruction,Neuroregeneration&Neurorestoration Professional Committee,Association of Chinese Research Hospital,Sino-Canada Spinal and Spinal Cord Injury Center | 2023 | Chinese Journal of Traumatology2023，26，1： | 2 |
| 5 | Lipopolysaccharide decreasing albumin expression in rat hepatocytes显示文摘The relations of the severity of hypoalbu-minemia to morbidity and mortality of patients with critical illness illustrate the need for better understanding of molecular mechanism of hypoalbuminemia. This study was undertaken to investigate the response of albumin synthesis to lipopolysaccharide(LPS)in rat hepatocytes in vitro in early acute phase of sepsis. METHODS:Hepatocytes were cultured at an initial cell density of 1.5×106 cells/well in 3 ml culture medium. There were two groups of samples which received either normal saline or 1 μg/L LPS randomly. Albumin mRNA in hepatocytes was assessed by reverse transcription-poly-merase chain reaction(RT-PCR) and albumin level in the supernatant was measured by ELISA at 0,2,8,12,24 hours after exposure. Meanwhile, the albumin precursor was evaluated at the same time points by flow cytometry. RESULTS:The quantitative changes of mRNA, albumin precursor and its protein were analogous. All of them tended to decline at 12 hours post-treatment and did not decrease significantly until 24 hours after LPS exposure. Meanwhile, albumin mRNA decreased about 30% and the levels of albumin precursor and albumin reduced approximately 50%. CONCLUSIONS: LPS can inhibit albumin synthesis in rat hepatocytes by prevention of albumin transcription. Moreover, the response of hepatic albumin synthesis to LPS changes with the stage of sepsis process. The results show that albumin metabolism in sepsis is a complicated process and further studies are required to understand the molecular mechanism of LPS-induced hypoalbuminemia in sepsis. | Research Institute of General Surgery, Jinling Hospital, Nanjing 210002, China (Wang XY, Li WQ, Li N and Li JS) and Department of Orthopaedics, Zhongda Hospital, Nanjing 210009, China (Lu J) | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 2 |
| 6 | Nonunion following intramedullary nailing of the femur with and without reaming:results of a multicenter random ized clinical trial显示文摘 | Canadian Orthopaedic Trauma Society | | 0，，： | 1 |
| 7 | Japanese Orthopaedic As- sociation scoring system for cervical spondylotic myelopathy (in Japanese) 显示文摘 | Japanese Orthopaedic Association | 1976 | Nippon Seikeigeka Gakkai Zasshi1976，50，： | 1 |
| 8 | Assessment of surgical treatment of low back pain (1984-)显示文摘 | Japanese Orthopaedic Association | 1984 | J Jpn Orthop Assoc1984，58，12： | 1 |
| 9 | Assessnent of surgical treatment of low back pain(1984)显示文摘 | Japanese Orthopaedic Association | 1984 | J Jpn Orthop Assoc1984，58，12： | 1 |
| 10 | Surgical site infection prevention and control:an emerging paradigm显示文摘 | American Academy of Orthopaedic Surgeons Patient Safety Committee Evans RP | 2009 | J Bone Joint Surg Am2009，91，6： | 1 |
| 11 | Assessment of surgical treatment of low back pain显示文摘 | Japanese Orthopaedic Association | 1984 | J Jpn Orthop Associ1984，58，10： | 1 |
| 12 | Assesment of surgical treatment oflow back pain显示文摘 | | 1984 | J Jpn O rthop Assoc1984，58，： | 1 |
| 13 | Assessment of surgical treatment to flow back pain显示文摘 | Japanese Orthopaedic Association | 1984 | J Jpn Orthop Assoc1984，58，12： | 1 |
| 14 | Assessment of surgical treatment of low back显示文摘 | Japanese Orthopaedic Association | 1984 | Jpn Orthop Assoc1984，58，： | 1 |
| 15 | Nonunion following intramedullary nailing of the femur with and without reaming:results of a mulitcenter randomized clinical trial显示文摘 | Canadian Orthopaedic Trauma Society | 2003 | J Bone Joint Surg(Am)2003，85，： | 1 |
| 16 | Nonoperative treatment compared with plate fixation of displaced midshaft clavicular fractures,A muhicenter, randomized clinical trial显示文摘 | Canadian Orthopaedic Trauma Society | 2007 | J Bone Joint Surg(Am)2007，89，1： | 1 |
| 17 | Non- operative treatment compared with plate fixation of displaced midshaft clavicular fractures 显示文摘 | Altamini SA McKee MD Canadian orthopaedic trauma society | 2008 | J Bone Joint Surg Am2008，90，2： | 1 |
| 18 | Assessment of surgical treatment of low back pain显示文摘 | Japanese Orthopaedic Association | 1984 | J Jpn Orthop Associ1984，58，10： | 1 |
| 19 | Guidelines for the prevention of venous thromboembolism in major surgery in the department of orthopedics 显示文摘 | The Chinese Medical Association Orthopaedic Society | 2016 | Chin J Orthopaedics2016，36，2： | 1 |
| 20 | Expert con- sensus on screening and treatment of deep venous thrombosis in pa- tients with trauma department of orthopedics显示文摘 | The Chinese Medical Association Orthopaedic Society | 2013 | Chin J Orthopae- dic Trauma2013，15，12： | 1 |
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