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| 1 | Area under the curve of methotrexate and creatinine clearance are outcome - determining factors in primary CNS lymphomas显示文摘Although high-dose methotrexate(HD-MTX)is the most effective drug against primary CNS lymphomas(PCNSL),outcome-de-termining variables related to its administration schedule have not been defined.The impact on toxicity and outcome of the area under thecurve(AUC(MTX)),dose intensity(DI(MTX))and infusion rate(IR(MTX))of MTX and plsamatic creatinine clearance(CL(crea))was investigated in a retrospective series of 45 PCNSL patients treated with three different HD-MTX-basedcombinations.Anticon-vulsants were administered in 31 pts(69%).Age>60 years,anticonvulsant therapy,slow IR(MTX)(=800 mgm(-2)h(-1)),and reduced DI(MTX)(=1000 mgm(-2)wk(-1))were significantly correlated with low AUC(MTX)values.Seven pa- | FerreriAJ GuerraE RegazziM PasiniF AmbrosettiA PivnikA GubkinA CalderoniA SpinaM BrandesA FerrareseF RognoneA GoviS Dell’OroS LocatelliM VillaE ReniM | 2004 | 中国神经肿瘤杂志2004,2,1: | 9 |
| 2 | High-temperature mechanical properties of aluminium alloys reinforced with titanium diboride (TiB_2) particles显示文摘The physical and mechanical properties of metal matrix composites were improved by the addition of reinforcements.The mechanical properties of particulate-reinforced metal-matrix composites based on aluminium alloys (6061 and 7015) at high temperatures were studied.Titanium diboride (TiB2) particles were used as the reinforcement.All the composites were produced by hot extrusion.The tensile properties and fracture characteristics of these materials were investigated at room temperature and at high temperatures to determine their ultimate strength and strain to failure.The fracture surface was analysed by scanning electron microscopy.TiB2 particles provide high stability of the aluminium alloys (6061 and 7015) in the fabrication process.An improvement in the mechanical behaviour was achieved by adding TiB2 particles as reinforcement in both the aluminium alloys.Adding TiB2 particles reduces the ductility of the aluminium alloys but does not change the microscopic mode of failure,and the fracture surface exhibits a ductile appearance with dimples formed by coalescence. | J.Ooro | 2011 | Rare Metals2011,30,2: | 5 |
| 3 | Correlation between Ozone and Total VOCs in Printing Environment显示文摘 | Kiurski Jelena Adamovie Dragan Oros Ivana Krstie Jelena Adamovie Savka Vojinovie Miloradov Mirjana Kovacevic Ilija | 2011 | Journal of Chemistry and Chemical Engineering2011,5,5: | 3 |
| 4 | Removal of synthetic dyes from wastewaters: a review显示文摘 | Esther Forgacs Tibor Cserháti Gyula Oros | 2004 | Environment International2004,,7: | 3 |
| 5 | Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source显示文摘BACKGROUND The trans-fat containing AMLN(amylin liver non-alcoholic steatohepatitis,NASH)diet has been extensively validated in C57BL/6J mice with or without the Lep^ob/Lep^ob(ob/ob)mutation in the leptin gene for reliably inducing metabolic and liver histopathological changes recapitulating hallmarks of NASH.Due to a recent ban on trans-fats as food additive,there is a marked need for developing a new diet capable of promoting a compatible level of disease in ob/ob and C57BL/6J mice.AIM To develop a biopsy-confirmed mouse model of NASH based on an obesogenic diet with trans-fat substituted by saturated fat.METHODS Male ob/ob mice were fed AMLN diet or a modified AMLN diet with trans-fat(Primex shortening)substituted by equivalent amounts of palm oil[Gubra amylin NASH,(GAN)diet]for 8,12 and 16 wk.C57BL/6J mice were fed the same diets for 28 wk.AMLN and GAN diets had similar caloric content(40%fat kcal),fructose(22%)and cholesterol(2%)level.RESULTS The GAN diet was more obesogenic compared to the AMLN diet and impaired glucose tolerance.Biopsy-confirmed steatosis,lobular inflammation,hepatocyte ballooning,fibrotic liver lesions and hepatic transcriptome changes were similar in ob/ob mice fed the GAN or AMLN diet.C57BL/6J mice developed a mild to moderate fibrotic NASH phenotype when fed the same diets.CONCLUSION Substitution of Primex with palm oil promotes a similar phenotype of biopsyconfirmed NASH in ob/ob and C57BL/6J mice,making GAN diet-induced obese mouse models suitable for characterizing novel NASH treatments. | Michelle L Boland Denise Oro Kirstine S T■lb■l Sebastian T Thrane Jens Christian Nielsen Taylor S Cohen David E Tabor Fiona Fernandes Andrey Tovchigrechko Sanne S Veidal Paul Warrener Bret R Sellman Jacob Jelsing Michael Feigh Niels Vrang James L Trevaskis Henrik H Hansen | 2019 | World Journal of Gastroenterology2019,25,33: | 3 |
| 6 | 表观难治性高血压患者的交感神经活性和动脉压力反射功能显示文摘与非难治性高血压相比,真性难治性高血压(resistant hypertension,RHT)的特征是肾上腺素能神经的显著激活和反射改变。然而该特征是否是RHT特有的还是和表观RHT(apparent RHT,ARHT)共有的,仍不清楚。 | 陈嘉睿 练桂丽 Dell’Oro R Quarti-Trevano F Seravalle G Zanchettin F Bertoli S Airoldi F Mancia G Grassi G | 2019 | 中华高血压杂志2019,27,10: | 2 |
| 7 | Effect of central and peripheral body fat distribution on sympathetic and baroreflex function in obese normotensives显示文摘 | Grassi G Dell'Oro R Facchini A | 2004 | J Hypertens2004,22,12: | 1 |
| 8 | Effect of central and peripheral body fat distribution on sympathetic and baroreflex function in obese normotensives显示文摘 | Grassi G Dell'Oro R Facchini A | 2004 | J Hypertens2004,22,12: | 1 |
| 9 | Numerical simulation of the unsteady stator-rotor interaction in a low-speed axial fan including experimental validation显示文摘 | Fernendez Oro J M Argttclles Diaz K M SantolariaMorros C | 2011 | International Journal of Numerical Methods for Heat & Fluid Flow2011,21,2: | 1 |
| 10 | Combined treatment with high-dose methotrexate, vincristine and procarbazine, without intrathecal chemotherapy, followed by consolidation radiotherapy for primary central nervous system lymphoma in immunocompetent patients显示文摘 | Ferreri AJ Reni M Dell'OroS | 2001 | Oncology2001,60,2: | 1 |
| 11 | Autoimmune thyroiditisassociated with polycystic ovary syndrome:Comments about 25cases显示文摘 | Gudovan E Diaconescu C Oros S | 2008 | Acta Endocrinologica(Buc)2008,4,2: | 1 |
| 12 | Surfaetant protein(SP) B associa- tions and interactions with SP-A in white and black subjects with re- spiratory distress syndrome 显示文摘 | ~oros J Fan R Diangelo S | 2001 | Pediatr Int2001,43,6: | 1 |
| 13 | Basal cell carcinomas in mice overexpressing sonic hedgehog显示文摘 | Oro AE Higgins KM Hu Z | 1997 | Science1997,276,5313: | 1 |
| 14 | Levels and distribution of polybrominated diphenyl ethers in water, surface sediments, and bivalves from the San Francisco estuary 显示文摘 | Oros D R Hoover D Rodigari F | 2005 | Environmental Science and Technology2005,39,1: | 1 |
| 15 | Polybrominated diphenyl ethers in Cali- fornia wastestreams显示文摘 | Petreas M Oros D | 2009 | Chemosphere2009,74,7: | 1 |
| 16 | Biomass Burning as the Main Source of Organic Aerosol Particulate Matter in Malaysia during Haze Episodes显示文摘 | Radzibin Abas M Oros D R Simoneit B R T | 2004 | Chemosphere2004,55,8: | 1 |
| 17 | Identification and emission rates of molecular tracers in coal smoke particulate matter显示文摘 | D.R. Oros B.R.T. Simoneit | 2000 | Fuel2000,,5: | 1 |
| 18 | Biological activity and environmental impact of anionic surfactants显示文摘 | CSERH(A)TI T FORG(A)CS E OROS G | 2002 | Environment International2002,28,5: | 1 |
| 19 | Intestinal eryptosporidio- sis in pigeons ( Columba livia) 显示文摘 | Rodriguez F J Oros J L Rodriguez | 1997 | Avian Diseases1997,41,3: | 1 |
| 20 | The tumour specific pro-apoptotic factor apoptin ( VP3 ) from chicken anaemia virus显示文摘 | Oro C Jans DA | 2004 | Curr Drug Targets2004,5,2: | 1 |