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6篇 您的检索式:作者名="Offringa Remko"
    题名 作者 年代 出处 被引量
1Phosphorylation‐dependent Traffcking of Plasma Membrane Proteins in Animal and Plant Cells显示文摘In both unicellular and multicellular organisms,transmembrane(TM)proteins are sorted to and retained at specifc membrane domains by endomembrane traffcking mechanisms that recognize sorting signals in the these proteins.The traffcking and distribution of plasma membrane(PM)‐localized TM proteins(PM proteins),especially of those PM proteins that show an asymmetric distribution over the PM,has received much attention,as their proper PM localization is crucial for elementary signaling and transport processes,and defects in their localization often lead to severe disease symptoms or developmental defects.The subcellular localization of PM proteins is dynamically regulated by post‐translational modifcations,such as phosphorylation and ubiquitination.These modifcaitons mostly occur on sorting signals that are located in the larger cytosolic domains of the cargo proteins.Here we review the effects of phosphorylation of PM proteins on their traffcking,and present the key examples from the animal feld that have been subject to studies for already several decades,such as that of aquaporin 2 and the epidermal growth factor receptor.Our knowledge on cargo traffcking in plants is largely based on studies of the family of PIN FORMED(PIN)carriers that mediate the effux of the plant hormone auxin.We will review what is known on the subcellular distribution and traffcking of PIN proteins,with a focus on how this is modulated by phosphorylation,and identify and discuss analogies and differences in traffcking with the well‐studied animal examples.Remko Offringa Fang Huang 2013Journal of Integrative Plant Biology2013,55,9:4
2An INDEHISCENT-Controlled Auxin Response Specifies the Separation Layer in Early Arabidopsis Fruit显示文摘种子疏开是在植物种的生命周期的一重要时刻。在 Arabidopsis thaliana,它依赖于抄写因素果皮不裂(IND ) 调停了在裂开地区的分离层的说明在在阀门(心皮墙) 和发展中的水果的中央洋梅之间的边缘发现了。IND 由在水果开发的迟了的阶段导致本地植物生长素最小指定分离层,这被建议。这里,我们证明 ind 异种和野类型的水果之间的词法差别已经在水果开发的早阶段产生,与在阀门边缘的强壮的 IND 表示与一致。我们证明减少 IND 的 PIN-FORMED3 (PIN3 ) 植物生长素流出搬运人丰富在早水果开发期间在阀门边缘导致增加的植物生长素回答,并且形成裂开地区的伴随物房间部门缺乏 ind 变异的水果。而且, AGC kinases PINOID (PID ) 的 IND 倡导者驱动的宫外的表示和 WAG2 由通过增加的 PIN3 丰富在水果开发的阶段 14-16 从阀门边缘驱逐植物生长素导致了 indehiscence。我们的结果证明除它在 Arabidopsis 水果开发的迟了的阶段的角色以外, IND 在早阶段工作便于形成裂开地区的被触发植物生长素的房间部门。Kasper van Gelderen Martin van Rongen An'an Liu Anne Otten Remko Offringa 2016Molecular Plant2016,9,6:3
3Regulation of auxin transport polarity by AGC kinases显示文摘HE(E) L(E) NE S ROBERT REMKO OFFRINGA 2008Current Opinion in Plant Biology2008,,11:1
4Ectopicexpression of baby boom triggers a conversion from vegetative toembryonic growth显示文摘Boutilier Kim Offringa Remko Sharma Vijay K 2002The Plant Cell2002,14,8:1
5Toward a Molecular Understanding of Plant Hormone Actions显示文摘Chuanyou Li Jiayang Li Kang Chong Klaus Harter Youngsook Lee Jeffrey Leung Enrico Martinoia Makoto Matsuoka Remko Offringa Lijia Qu Julian Schroeder Yunde Zhao 2016Molecular Plant2016,9,1:0
6Cell Polarity and Development显示文摘All cells show some degree of polarity,either by asymmetrically distributed membrane or cytosolic components.Even in bacterial cells that do not have the eukaryotic membrane compartmentalization of the cytoplasm,proteins can be localized at specifc areas.In rod‐shaped bacteria,many processes such as signaling,fagella formation,and DNA uptake occur at the cell poles.In addition,the symmetry of cell division inRemko Offringa Jürgen Kleine‐Vehn 2013Journal of Integrative Plant Biology2013,55,9:0
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