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| 1 | Viral and host causes of fatty liver in chronic hepatitis B显示文摘AIM: To investigate the viral and host causes of fatty liver in chronic hepatitis B patients and the role of fat deposits in liver damage.METHODS: A total of 164 patients (113 males and 51 females, average age 35±11.3 years, and range 10-62 years) with previously untreated chronic hepatitis B were included in the study. The patients were divided into two groups depending on the result of liver biopsy: group without steatosis (100 patients with <5% hepatosteatosis) and group with steatosis (64 patients with >5% hepatosteatosis). The groups were compared in terms of gender, body mass index (BMI), liver enzymes (ALT, AST, ALP, GGT), cholesterol, triglyceride, HBeAg, viral load, and histological findings. In the group with steatosis, the patients were subdivided depending on the degree of steatosis into mild group (45 patients with 5-24% steatosis), and severe group (19 patients with >25% steatosis). RESULTS: In the group of chronic hepatitis B with steatosis, the mean age, BMI, cholesterol, and triglyceride levels were significantly higher than those in the group without steatosis (P<0.05). Steatosis was found in 53 (46.9%) of male patients and 11 (22%) of female patients (P<0.05). No significant difference was found in the positivity of ALT, AST, ALP, GGT, HBeAg, viral load, histological activity index (HAI) and stage between the two groups (P>0.05). In the group with severe steatosis, the BMI was significantly higher than that in the group with mild steatosis (P<0.05). No significant difference was found in the other parameters between the groups (P>0.05). CONCLUSION: Steatosis in chronic hepatitis B appears to be a result of metabolic factors of the host rather than the effect of viruses. Steatosis is unrelated to the HAI and degree of fibrosis, which are considered as the histological indicators of liver damage. | Emin Altiparmak Seyfettin K(o|¨)klü Mesut Yalinkilic Osman Yüksel Bahattin Cicek Ertugrul Kayacetin Tülin Sahin | 2005 | World Journal of Gastroenterology2005，11，20： | 52 |
| 2 | 年龄相关性黄斑变性的脉络膜厚度评价(英文)显示文摘目的:通过光学相干断层扫描(optical coherence tomography,OCT;RTVue 100-2;V 5.1,Optovue,Fremont,CA,USA)测量比较非新生血管性与新生血管性年龄相关性黄斑变性(age-related macular degeneration,AMD)黄斑中心凹下脉络膜厚度(subfoveal choroidal thickness,SFCT),并分析脉络膜厚度(choroidal thickness,CT)对AMD新血管形成的影响。方法:本研究为回顾性、横断面研究。以单侧眼患有新生血管性AMD且对侧眼患有非新生血管性AMD的24例患者(48眼)作为研究组,选取年龄与眼轴长度相匹配的40例健康眼作为对照组。非新生血管性AMD亚组研究对象是黄斑区有玻璃疣和/或色素变化眼,而新生血管性AMD亚组研究对象是由于脉络膜新生血管而致视网膜下或视网膜内有渗出液和/或脂性渗出眼。运用OCT垂直测量外侧高反射线(视网膜色素上皮层)到脉络膜巩膜交界面间的距离。选取7个不同点进行脉络膜厚度测量,测量区域为距黄斑中心凹颞侧和鼻侧1500μm范围,测量间距为500μm。测量结果在亚组间进行统计学对比研究。结果:研究组患者平均年龄为72.4±8.97(60~82)岁,对照组受试者平均年龄为71.2±8.8(58~81)岁。新生血管性AMD组中平均SFCT明显大于非新生血管性AMD组的厚度(P<0.05)。非新生血管性AMD组中,平均SFCT与平均鼻、颞侧脉络膜厚度比较,差异无统计学意义(P>0.05);而新生血管性AMD组中,平均SFCT与平均鼻、颞侧脉络膜厚度比较,差异有统计学意义(P<0.05)。结论:运用OCT对脉络膜厚度进行测量,有助于理解AMD的病理生理机制。然而,仍需要大型前瞻性研究来探求新生血管性AMD中SFCT增厚的原因。 | Erkan Unsal Kadir Eltutar Ozen Ayranci Osmanbasoglu Sibel Zιrtιloglu Osman Kιzιlay Hulya Gungel | 2014 | 国际眼科杂志2014，14，9： | 4 |
| 3 | Investigation of soliton solutions with different wave structures to the(2+1)-dimensional Heisenberg ferromagnetic spin chain equation显示文摘The principal objective of this article is to construct new and further exact soliton solutions of the(2+1)-dimensional Heisenberg ferromagnetic spin chain equation which investigates the nonlinear dynamics of magnets and explains their ordering in ferromagnetic materials.These solutions are exerted via the new extended FAN sub-equation method.We successfully obtain dark,bright,combined bright-dark,combined dark-singular,periodic,periodic singular,and elliptic wave solutions to this equation which are interesting classes of nonlinear excitation presenting spin dynamics in classical and semi-classical continuum Heisenberg systems.3D figures are illustrated under an appropriate selection of parameters.The applied technique is suitable to be used in gaining the exact solutions of most nonlinear partial/fractional differential equations which appear in complex phenomena. | M S Osman K U Tariq Ahmet Bekir A Elmoasry Nasser S Elazab M Younis Mahmoud Abdel-Aty | 2020 | Communications in Theoretical Physics2020，72，3： | 4 |
| 4 | Serum beta 2-microglobulin as a biomarker in inflammatory bowel disease显示文摘AIM: To investigate the diagnostic utility of beta 2 microglobulin(B2-M) levels and analyze this correlation with the activity of inflammatory bowel disease(IBD).METHODS: Overall, 78 IBD patients and 30 healthy controls were enrolled in the study. We examined B2-M serum levels in 43 ulcerative colitis(UC) patients, 35 with Crohn's disease(CD) and 30 control subjects, using an enzymatic method. Patients were divided into two groups according to two disease types: active and in remission. Subjects were also divided into two subgroups according to extent of the disease: left-side and pancolitis for UC and ileitis and ileocolitis for CD. All groups were compared for mean serum B2-M levels and also examined to see whether there was a correlation between serum B2-M levels and other inflammatory markers.RESULTS: The mean serum B2-M levels in the control group, UC and CD were 1.71, 2.41 and 2.24 respectively. B2-M values ≥ 1.96 mg/L had a 62% sensitivity, 76% specificity, a 79% positive predictive value, and a 58% negative predictive value for UC patients. B2-Mvalues ≥ 1.70 mg/L had 80% sensitivity, 53% specificity, 66% positive predictive value, and 69% negative predictive value for CD patients. Mean B2-M values were significantly higher in ulcerative colitis and Crohn's disease patients than in healthy controls(UC 2.41 ± 0.87 vs 1.71 ± 0.44, P = 0.002; CD 2.24 ± 1.01 vs 1.71 ± 0.44, P = 0.033). Also, mean B2-M values were significantly higher in active disease when compared to patients in remission(UC 2.66 ± 0.92 vs 1.88 ± 0.41, P = 0.004; CD 2.50 ± 1.15 vs 1.73 ± 0.31, P = 0.033). The difference between groups(UC and CD) in terms of serum B2-M levels was statistically insignificant(2.41 ± 0.87 vs 2.24 ± 1.01, P > 0.05 respectively).CONCLUSION: Serum B2-M levels may be used as an activity parameter in IBD. | Bülent Y|lmaz Seyfettin Kklü Osman Yüksel Serap Arslan | 2014 | World Journal of Gastroenterology2014，20，31： | 3 |
| 5 | Productivity growth in OECD countries: A comparison with Malmquist indices显示文摘 | Bar?? K. Y?rük Osman Zaim | 2005 | Journal of Comparative Economics2005，，2： | 2 |
| 6 | Disseminated intravascular coagulation in liver cirrhosis: fact or fiction?显示文摘 | Ziv Ben-Ari Elsvir Osman Ronald A Hutton Andrew K Burroughs | 1999 | The American Journal of Gastroenterology1999，，10： | 2 |
| 7 | Developments in characterization of resistance spot welding of aluminum 显示文摘 | HAO M Osman K A | 1996 | Welding Journal1996，75，1： | 2 |
| 8 | Successful pregnancy in a patient with polycystic kidney disease and advanced renal failure without prophylactic dialysis 显示文摘 | Hassan K Weissmam I Osman S | 2001 | Nephron2001，87，1： | 1 |
| 9 | Activation of a putative MAP kinase in pollen is stimulated by the self-incompatibility response显示文摘 | RUDD J OSMAN K FRANKLIN F | 2003 | FEBS Letters2003，547，： | 1 |
| 10 | Percutaneousnephrolithotomy with ultrasonography guided renal ac- cess:experience from over 300 cases显示文摘 | Osman M Wendt-nordahl G Heger K | 2005 | BJU2005，96，6： | 1 |
| 11 | Seroprevalence of antibodies to human herpesviruses in England and Hong Kong显示文摘 | Kangro H O Osman H K Lau Y L | 1994 | J Med Virol1994，43，1： | 1 |
| 12 | Fracture of self-expand- ing nitinol stents stressed in vitro under simulated intravascular conditions显示文摘 | Nikanorov A Smouse HB Osman K | 2008 | J Vasc Surg2008，48，2： | 1 |
| 13 | Numericalsolution of the general two-dimensional inverse heatconduction problem(IHCP)显示文摘 | OSMAN A M DOWDING K J BECK J V | 1997 | Journal of HeatTransfer1997，119，： | 1 |
| 14 | Percutaneous nephrolithoto my with ultrasonography-guided renal access:experience from over 300cases显示文摘 | Osman M Wendt Nordahl G Heger K | 2005 | BJU Int2005，96，： | 1 |
| 15 | Photosynthetic performance and adaptation of sugarcane at suboptimal temperatures显示文摘 | Ebrahim M K H Vogg G Osman M N E H Komor E | 1988 | Journal of Plant Physiology1988，153，5： | 1 |
| 16 | Underwater Image Enhancement Using an Integrated Colour Model 显示文摘 | Iqbal K Salam R A Osman A | 2007 | IAENG International Journal of Computer Science2007，34，2： | 1 |
| 17 | Insulin resistance differentially affects the PI 3-kinase-and MAP kinase-mediated signaling in human muscle显示文摘 | Cusi K Maezono K Osman A | 2000 | J Clin Invest2000，105，3： | 1 |
| 18 | Economic lot and delivery scheduling problem for multi-stage supply chains显示文摘 | OSMAN H DEMIRLI K | 2012 | International Journal of Production Economics2012，136，2： | 1 |
| 19 | The Determinants of Recycling Intention Behavior among the Malaysian School Students : An Applica- tion of Theory of Planned Behavior显示文摘 | MAHMUDS N D OSMAN K | 2010 | Procedia Social and Behavioral Sciences2010，，9： | 1 |
| 20 | Reduction in serum levels of adhesion molecules,interleukin-6 and C-reactive protein following short-term low-dose atorvastatin treatment in patients with non-familial hypercho lesterolemia显示文摘 | Osman NS Yusoff K | 2003 | Horm Metab Res2003，35，： | 1 |
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