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| 1 | Apoptosis and mitosis in gonocytes of the rat testis during foetal and neonatal development显示文摘 | BOULOGNE B OLASO R LEVACHER C | 1999 | Int J Androl1999，22，6： | 1 |
| 2 | Apoptosis and mitosis in gonocytes of the rat testis during foetal and neonatal development显示文摘 | BOULOGNE B OLASO R LEVACHER C | 1999 | Int J Androl1999，22，6： | 1 |
| 3 | The serine/threonine transmembrane receptor ALK2 mediates Müllerian inhibiting substance signaling显示文摘 | Visser JA Olaso R Verhoef-Post M | 2001 | Molecular Endocrinology2001，15，： | 1 |
| 4 | Transforming growth factor β3 in the fetal and neonatal rat testis: immunolocalization and effect on fetal Leydig cell function显示文摘 | Olaso R Pairault C Saez J | 1999 | Histochem Cell Biol1999，112，3： | 1 |
| 5 | The immunohistochemical localization of transforming growth factor-β2 in the fetal and neonatal rat testis显示文摘 | Olaso R Gautier C Levacher C | 1997 | Mol Cell Endocrinol1997，126，2： | 1 |
| 6 | Transforming growth factor beta 3 in the fetal rat testis: immunolocalization and effect on fetal Leydig cell function 显示文摘 | Olaso R Pairault C Saez J | 1999 | Histochem Cell Biol1999，112，3： | 1 |
| 7 | Transforming growth factor β1 and β32 reduce the mumber of gonocytes by increasing apoptosis 显示文摘 | Olaso R Pairault C Boulogne B | 1998 | Endocrinology1998，139，2： | 1 |
| 8 | The serine / threonine transmembrane receptor ALK2 mediates Mullerian inhibiting substance signaling 显示文摘 | Visser JA Olaso R Verhoef-Post M | 2001 | Mol Endocrinol2001，15，6： | 1 |
| 9 | Apoptosis and mitosis in gonocytes of the rat testis during foetal and neonatal development显示文摘 | Boulogne B Olaso R Levacher C | 1999 | Intemet J Androl1999，22，6： | 1 |
| 10 | Expression of type Ⅰ and type Ⅱ receptors for transforming growth factor beta in the adult rat testis显示文摘 | PAIRAULT C HABERT R | 1998 | Histochem Cell Biol1998，110，6： | 1 |
| 11 | The immunohistochemical localization of transforming growth factor beta in the fetal and neonatal rat testis显示文摘 | Olaso R Gautier C Levacher C | 1997 | Mol Cell Endocrinol1997，126，： | 1 |
| 12 | Expression of type Ⅰ and Ⅱ receptors for transforming growth factor beta in the adult rat testis显示文摘 | Olaso R Pairault C Habert R | 1998 | Histochem Cell Biol1998，110，： | 1 |
| 13 | Wnt4 overexpression disrupts normal testicular vaseulature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy 显示文摘 | Jordan BK Shen JH Olaso R | 2003 | Proe Natl Acad Sci USA2003，100，10： | 1 |
| 14 | Hypermethylation of the IGF2 differentially methylated region 2 is a specific event in insulinomas leading to loss-of-imprinting and overexpression显示文摘 | DEJEUX E OLASO R DOUSSET B | 2009 | Endocr Relat Cancer2009，16，3： | 1 |
| 15 | The serine/threonine transmembrane receptor ALK2 mediates Mullerian inhibiting sub- stance signaling 显示文摘 | Visser J A Olaso R Verhoef-Post M | 2001 | Molecular Endocrinology2001，15，6： | 1 |
| 16 | Transforming growth fac tor beta1 and beta 2 reduce the number of gonocytes by increasing apoptosis显示文摘 | Olaso R Pairault C Boulogne B | 1998 | Endocrinology1998，139，2： | 1 |
| 17 | Trans- forming growth factor 133 in the fetal and neonatal rat testis: immunolocalization and effect on fetal Leydig cell function显示文摘 | OLASO R PAIRAULT C SAEZ J M | 1999 | Histochem Cell Biol1999，112，3： | 1 |
| 18 | Transforming growth factor-beta 1 and beta 2 reduce the number of gonocytes by increasing apoptosis显示文摘 | Olaso R Pairault C Boulogne B | | 0，，02： | 1 |
| 19 | Genetic factors for differentiated thyroid cancer in French Polynesia:new candidate loci显示文摘Background:Populations of French Polynesia(FP),where France performed atmospheric tests between 1966 and 1974,experience a high incidence of differentiated thyroid cancer(DTC).However,up to now,no sufficiently large study of DTC genetic factors in this population has been performed to reach definitive conclusion.This research aimed to analyze the genetic factors of DTC risk among the native FP populations.Methods:We analyzed more than 300000 single nucleotide polymorphisms(SNPs)genotyped in 283 DTC cases and 418 matched controls born in FP,most being younger than 15 years old at the time of the first nuclear tests.We analyzed the genetic profile of our cohort to identify population subgroups.We then completed a genome-wide analysis study on the whole population.Results:We identified a specific genetic structure in the FP population reflecting admixture from Asian and European populations.We identified three regions associated with increased DTC risk at 6q24.3,10p12.2,and 17q21.32.The lead SNPs at these loci showed respective p-values of 1.66×10^(−7),2.39×10^(−7),and 7.19×10^(−7) and corresponding odds ratios of 2.02,1.89,and 2.37.Conclusion:Our study results suggest a role of the loci 6q24.3,10p12.2 and 17q21.32 in DTC risk.However,a whole genome sequencing approach would be better suited to characterize these factors than genotyping with microarray chip designed for the Caucasian population.Moreover,the functional impact of these three new loci needs to be further explored and validated. | Monia Zidane Marc Haber Thérèse Truong Frédérique Rachédi Catherine Ory Sylvie Chevillard Hélène Blanché Robert Olaso Anne Boland Éric Conte Mojgan Karimi Yan Ren Constance Xhaard Vincent Souchard Jacques Gardon Marc Taquet André Bouville Jean-François Deleuze Vladimir Drozdovitch Florent de Vathaire Jean-Baptiste Cazier | 2023 | Precision Clinical Medicine2023，6，2： | 0 |
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