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1Conservative treatment of knee osteoarthritis:A review of the literature显示文摘Knee osteoarthritis(KOA)is a common chronic debilitating disease with an estimated prevalence of 23.9%in the general adult population.The condition is characterised by joint pain,functional impairment and significant reduction in quality of life.Management for KOA can generally be divided into conservative(non-operative)and surgical(operative)measures.Conservative management broadly compromises pharmacological and non-pharmacological options and is conventionally the first line treatment to avoid or delay the need for surgical management.The aim of this study is to provide an overview of the current recommendations,efficacy and safety profile of different conservative treatments through a review of the literature.Wei Boon Lim Oday Al-Dadah 2022World Journal of Orthopedics2022,13,3:5
2Characterisation of Ba(OH) 2 –Na 2 SO 4 –blast furnace slag cement-like composites for the immobilisation of sulfate bearing nuclear wastes显示文摘Neda Mobasher Susan A. Bernal Oday H. Hussain David C. Apperley Hajime Kinoshita John L. Provis 2014Cement and Concrete Research2014,,:2
3Comparison between Pt/TiO_2/Pt and Pt/TaO_X/TaO_Y/Pt based bipolar resistive switching devices显示文摘Nonvolatile memories have emerged in recent years and have become a leading candidate towards replacing dynamic and static random-access memory devices.In this article,the performances of T1O2 and TaO2nonvolatile memristive devices were compared and the factors that make TaO2 memristive devices better than T1O2 memristive devices were studied.TaO2 memristive devices have shown better endurance performances(108times more switching cycles) and faster switching speed(5 times) than TiO2 memristive devices.Electroforming of TaO2 memristive devices requires 4.5 times less energy than TiO2 memristive devices of a similar size.The retention period of TaO2 memristive devices is expected to exceed 10 years with sufficient experimental evidence.In addition to comparing device performances,this article also explains the differences in physical device structure,switching mechanism,and resistance switching performances of TiO2 and TaO2 memristive devices.This article summarizes the reasons that give TaO2 memristive devices the advantage over TiO2 memristive devices,in terms of electroformation,switching speed,and endurance.Patrick W.C.Ho Firas Odai Hatem Haider Abbas F.Almurib T.Nandha Kumar 2016Journal of Semiconductors2016,37,6:2
4Mesuaferrea stem bark extract induces apoptosis and inhibits metastasis in human colorectal carcinoma HCT 116 cells, through modulation of multiple cell signalling pathways显示文摘Considering the great potential of natural products as anticancer agents, the present study was designed to explore the molecular mechanisms responsible for anticancer activities of Mesua ferrea stem bark extract against human colorectal carcinoma. Based on MTT assay results, bioactive sub-fraction(SF-3) was selected for further studies using HCT 116 cells. Repeated column chromatography resulted in isolation of less active α-amyrin from SF-3, which was identified and characterized by GC-MS and HPLC methods. α-amyrin and betulinic acid contents of SF-3 were measured by HPLC methods. Fluorescent assays revealed characteristic apoptotic features, including cell shrinkage, nuclear condensation, and marked decrease in mitochondrial membrane potential in SF-3 treated cells. In addition, increased levels of caspases-9 and-3/7 levels were also observed in SF-3 treated cells. SF-3 showed promising antimetastatic properties in multiple in vitro assays. Multi-pathway analysis revealed significant down-regulation of WNT, HIF-1α, and EGFR with simultaneous up-regulation of p53, Myc/Max, and TGF-β signalling pathways in SF-3 treated cells. In addition, promising growth inhibitory effects were observed in SF-3 treated HCT 116 tumour spheroids, which give a hint about in vivo antitumor efficacy of SF-3 phytoconstituents. In conclusion, these results demonstrated that anticancer effects of SF-3 towards colon cancer are through modulation of multiple molecular pathways.Muhammad Asif Armaghan Shafaei Aman Shah Abdul Majid Mohammed Oday Ezzat Saad S Dahham Mohamed B.Khadeer Ahamed Chern Ein Oon Amin Malik Shah Abdul Majid 2017Chinese Journal of Natural Medicines2017,15,7:2
5Malaria elimination in Lao PDR:the challenges associated with population mobility显示文摘Although the Lao People’s Democratic Republic(Lao PDR)is comparatively small landlocked country with patterns of both in-and out-migration,its human migration situation has been poorly studied.This is despite all of the country’s 18 provinces sharing both official and unofficial border checkpoints with neighboring countries.Economic reforms in the last decade have seen a gradual increase in the promotion of foreign investment,and main towns and transportation networks have been expanding thus offering new opportunities for livelihoods and economic activities.In the last decade,there has also been a significant reduction of reported malaria cases in Lao PDR and while this is an important prerequisite for eliminating malaria in the country,malaria outbreaks reported in the last four years suggest that population mobility,particularly in the south,is an important factor challenging current control efforts.Bolder investment in social sector spending should be geared towards improving health service provision and utilization,ensuring equitable access to primary health care(including malaria)through efforts to achieve universal health coverage targets.This should be extended to populations that are mobile and migrants.The local government plays a critical role in supporting policy and enforcement issues related to private sector project development in the provinces.Cross-border initiatives with neighboring countries,especially in terms of data sharing,surveillance,and response,is essential.Mechanisms to engage the private sector,especially the informal private sector,needs to be explored within the context of existing regulations and laws.Existing and new interventions for outdoor transmission of malaria,especially in forest settings,for high-risk groups including short-and long-term forest workers and their families,mobile and migrant populations,as well as the military must be combined into integrated packages with innovative delivery mechanisms through social marketing approaches.This should happen at multiple points in the mobility pathway and involve the private sector rather than being fully reliant on the national malaria vertical program This article based on the review of existing literature from abstracts and full texts,includes published,peer-reviewed English language literature sourced through PubMed and grey literature sources through Google and Google Scholar.The review included also case reports,sector reports,conference proceedings,research reports,epidemiology studies,qualitative studies,and census reports in both Lao and English languages.The authors used the search terms:malaria and mobile populations,malaria control program and elimination,health system performance,malaria outbreak,Lao PDR;and included articles published until June 2015.Sengchanh Kounnavong Deyer Gopinath Bouasy Hongvanthong Chanthalone Khamkong Odai Sichanthongthip 2017Infectious Diseases of Poverty2017,6,1:2
6Increased serumlevels of soluble fractalkine ( CX3CL1) correlate with diseaseactivity in rheumatoid vasculitis显示文摘Matsunawa M Iso2aki T Odai T 2006Arthritis Rheum2006,54,11:1
7Regulation of cathelicidin antimicrobialpeptide expression by an endoplasmic reticulum(ER) stresssignaling,vitamin D receptor- independent pathway显示文摘Park K Elias PM OdaY 2011J BiolChem2011,286,34:1
8Improved survival with ip- ilimumab in patients with metastatic melanoma显示文摘Hodi FS ODay SJ McDermott DF 2010N Engl J Med2010,363,8:1
9Increased serum levels of soluble fractalkine (CX3CL1) correlate with disease activity in rheumatoid vasculitis显示文摘Matsunawa M Isozaki T Odai T 2006Arthritis Rheum2006,54,11:1
10Dynamics of haemolymph sorbitol-6-phosphate and its control by ecdystemid in the larvae of the silkworm,Bombyx mori显示文摘OdaY Iwami M Osanai M Sakurai S 0,,:1
11Differential ezrin and phos-phorylated ezrin expression profiles between pancreatic intraepi-thelial neoplasia,intraductal papillary mucinous neoplasm,and in-vasive ductal carcinoma of the pancreas显示文摘OdaY Aishima S Morimatsu K 2013Human Pathology2013,44,8:1
12Retinal manifestations of ophthalmic arteryhypoperfusion显示文摘Ong TJ Paine M ODay J 2002Clin Exp Ophthalmol2002,30,4:1
13Improved survival with ipilimumab in patients with metastatic melanoma显示文摘Hodi FS ODay SJ McDermott DF 2010N Engl J Med2010,363,8:1
14Metastatic melano- ma: chemotherapy to biochemoth therapy 显示文摘ODAY S J KIM C J REINTGENDS 2002Cancer Control2002,9,1:1
15Possible immunomodulating activities of carotenods in vitro cell culture experiments显示文摘Odai Y Higashi-Kdai K 1996Int J Immunopharmacol1996,18,12:1
16Correlation of CX3 CL1 and CX3CR1 levels with response to infliximab therapy in patients with rheumatoid arthritis 显示文摘Odai T Matsunawa M Takahashi R 2009J Rheumato12009,36,6:1
17Gelationtime and degr adation r ate of ch itosan- based injectable h y -dr ogel显示文摘Ganji F Abdek h odaie M J & Ramazani A S A 2007Jour nal of Sol- Gel Science and Tech nology2007,42,1:1
18A randomised, phase II study ofintetumumab, an anti-av-integrin mAb, alone and with dacarbazine instage IV melanoma 显示文摘ODay S Pavlick A Loquai C 2011Br J Cancer2011,105,3:1
19Correlation of CX3CL1 and CX3CR1 levels with response to infliximab thera- py in patients with rheumatoid arthritis 显示文摘Odai T Matsunawa M Takahashi R 2009J Rheumatol2009,36,6:1
20Flap thickness accuracy显示文摘Kerry D Solomon Eric Donnenfeld Helga P Sandoval Oday Al Sarraf Terrance J Kasper Mike P Holzer Elizabeth H Slate David T Vroman Flap Thickness Study Group 2004Journal of Cataract & Refractive Surgery2004,,5:1
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