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| 1 | Association between gastrointestinal symptoms and affectivity in patients with bipolar disorder显示文摘AIM To study if anxiety, depression and experience of stress are associated with gastrointestinal(GI) symptoms in patients with bipolar disorder.METHODS A total of 136 patients with bipolar disorder(mean age 49.9 years; 61% women) and 136 controls from the general population(mean age 51.0 years; 60% women) were included in the study. GI symptoms were assessed with The Gastrointestinal Symptom Rating Scale-irritable bowel syndrome(GSRS-IBS), level of anxiety and depression with The Hospital Anxiety and Depression Scale(HADS) and stress-proneness with Perceived Stress Questionnaire. Over a ten year period, all visits in primary care were retrospectively recorded in order to identify functional GI disorders.RESULTS In subjects with low total HADS-score, there were no significant differences in GI-symptoms between patients and controls(GSRS-IBS 7.0 vs 6.5, P = 0.513). In the patients with bipolar disorder there were significant correlations between all GSRS and HADS subscores for all symptom clusters except for 'constipation' and 'reflux'. Factors associated to GI symptoms in the patient group were female sex(adjusted OR = 2.37, 95%CI: 1.07-5.24) and high HADS-Depression score(adjusted OR = 3.64, 95%CI: 1.07-12.4). These patients had also significantly more visits for IBS than patients with low HADS-Depression scores(29% vs 8%, P = 0.008). However, there was no significant differences in consulting behaviour for functional GI disorders between patients and controls(25% vs 17%, P = 0.108).CONCLUSION Female patients and patients with high HADS depression score reported significantly more GI symptoms, whereas patients with low HADS scores did not differ from control subjects. | Pontus Karling Martin Maripuu Mikael Wikgren Rolf Adolfsson Karl-Fredrik Norrback | 2016 | World Journal of Gastroenterology2016，22，38： | 3 |
| 2 | Telomeres and telomerase in normal and malignant haematopoietic cells 显示文摘 | Norrback KF and Roos G | 1997 | Eur J Cancer1997，33，5： | 1 |
| 3 | Indoor environment: the significance of emission of formaldehyde and VOCs from newly painted indoor surfaces显示文摘 | Wieslander G Norrback D Bjornsson Asthma | 1997 | International Archives of Occupational and Environmental Health1997，69，： | 1 |
| 4 | The indivi- dual blood cell telomere attrition rate is telomere length dependent显示文摘 | Nordfjall K Svenson U Norrback KF | 2009 | PLoS Genet2009，5，10： | 1 |
| 5 | The individual blood cell telomere attrition rate is telomere length dependent显示文摘 | NORDFJALL K SVENSON U NORRBACK K F | | 0，，02： | 1 |
| 6 | Gastrointestinal symptoms are associated with hypothalamic-pituitary-adrenal axis suppression in healthy individuals显示文摘 | Pontus Karling Karl-fredrik Norrback Rolf Adolfsson ? ke Danielsson | 2007 | Scandinavian Journal of Gastroenterology2007，，11： | 1 |
| 7 | Telomerase activation in normal Blymphocytes and non-Hodgkin' s lymphomas显示文摘 | Dahlenborg K Calsson R | 1996 | Blood1996，88，1： | 1 |
| 8 | Telomerase activation in normal B lymphocytes and non-Hodgkin's lymphomas显示文摘 | NORRBACK K F DAHLENBORG K CARLSSON R | 1996 | Blood1996，88，1： | 1 |
| 9 | Telomeres and telomerase in normal and malignant haematopoietie cells 显示文摘 | NORRBACK K F ROOS G | 1997 | Eur J Cancer1997，33，5： | 1 |
| 10 | Telomeres and telomerase in normal and malignant haematopoietic cells显示文摘 | NORRBACK KF ROOS G | 1997 | Eur J Cancer1997，33，5： | 1 |
| 11 | Large-scale parent-child comparison confirms a strong paternal influence on telomere length显示文摘 | Nordfjll K Svenson U Norrback KF | 2010 | Eur J Hum Genet2010，18，3： | 1 |
| 12 | Telomere analysis by fluorescence in situ hybridization and flow cytometry显示文摘 | Hultdin M Gronlund E Norrback K F | 1998 | Nucleic Acids Res1998，26，16： | 1 |
| 13 | Telomerase activity in Hodgkin's disease显示文摘 | Norrback K F Enblad G Erlanson M | 1998 | Blood1998，92，2： | 1 |
| 14 | telomeraselength and telomerase activity in malignant Lymphomas at diagnosis and relapse显示文摘 | Remes K Norrback KF Rosenquist R | 2000 | Br J Cancer2000，82，3： | 1 |
| 15 | Telomere analysis by fluorescence in situ hybridization and flow cytometry显示文摘 | Hultdin M Gronlund E Norrback K | 1998 | Nucleic Acids Res1998，26，16： | 1 |
| 16 | Telomerse and telomerase in normal and malignant haematopoietic cells显示文摘 | Roos S | 1997 | Eur J Cancer1997，33，： | 1 |
| 17 | Telomere analysis by fluorescence in situ hybridization and flow cytometry显示文摘 | Hultdin M Gronlund E Norrback K | 1998 | Nucleic Acid Research1998，26，： | 1 |
| 18 | Telomerase regulation and telomere dynamics in germinal centers显示文摘 | Norrback KF Hultdin M Dahlenborg K | 2001 | Eur J Haematol2001，67，56： | 1 |
| 19 | Telomerase activity in Hodgkin's disease显示文摘 | Norrback KF Enblad G Erlanson M | 1998 | Blood1998，92，： | 1 |
| 20 | Telomerse and telomerase in normal and malignant haematopoietic cells显示文摘 | Norrback KF Roos S | 1997 | Eur J Cancer1997，33，： | 1 |
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