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2篇 您的检索式：作者名="Nobutoshi Funato"

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		题名	作者	年代	出处	被引量
	1	Globus sensation and increased upper esophageal sphincter pressure with distal esophageal acid perfusion显示文摘	Ryoji Tokashiki Nobutoshi Funato Mamoru Suzuki	2010	European Archives of Oto - Rhino - Laryngology2010，，5：	1
	2	Rikkunshito improves globus sensation in patients with proton-pump inhibitor-refractory laryngopharyngeal reflux显示文摘AIM: To investigate the effect of rikkunshito on laryngopharyngeal reflux(LPR) symptoms and gastric emptying in patients with proton-pump inhibitor(PPI)refractory LPR.METHODS: In total,22 patients with LPR were enrolled.Following a 2-wk treatment with PPI monotherapy,PPI-refractory LPR patients were randomly divided into two treatment groups(rikkunshito alone or rikkunshito plus the PPI,lansoprazole).LPR symptoms were assessed using a visual analog scale(VAS) score,gastrointestinal symptoms were assessed using the gastrointestinal symptom rating scale(GSRS),and gastric emptying was assessed using the radio-opaque marker method prior to and 4 wk following treatments.RESULTS: The 4-wk treatment with rikkunshito alone and with rikkunshito plus the PPI significantly decreased the globus sensation VAS scores.The VAS score for sore throat was significantly decreased following treatment with rikkunshito plus PPI but not by rik kunshito alone.Neither treatment significantly changed the GSRS scores.Rikkunshito improved delayed gastric emptying.We found a significant positive correlation between improvements in globus sensation and in gastric emptying(r2= 0.4582,P < 0.05).CONCLUSION: Rikkunshito improved globus sensation in patients with PPI-refractory LPR,in part,because of stimulation of gastric emptying.Thus,rikkunshito is an effective treatment for PPI-refractory LPR.	Ryoji Tokashiki Isaku Okamoto Nobutoshi Funato Mamoru Suzuki	2013	World Journal of Gastroenterology2013，19，31：	1

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