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| 1 | The Erythropoietin Receptor: Dimerization and Intracellular Signal Transduction显示文摘Erythropoietin (EPO), a 34 kD glycopro-tein, is the principal growth factor regulating theproduction of circulating erythrocytes; EPO isessential for committed CFU - E erythroid pro-genitors to divide several times and then to dif-ferentiate into erythrocytes. Like most receptorsfor hematopoietic growth factors, the erythro-poietin receptor (EPO - R) is a type I trans-membrane protein and a member of the cytokinereceptor superfamily. These receptors containfour conserved cysteines and a Trp - Ser - X - | WU Hong Harvey F Lodish(Whitehead Institute for Biomedical Research, Nine Cambridge Center Cambridge MA 02142 USA) (Department of Biology, Massachusetts Institute of Technology Cambridge MA 02139 USA) | 1996 | 中国实验血液学杂志1996,4,3: | 4 |
| 2 | Recognizing Local People's Priorities for Tropical Forest Biodiversity显示文摘热带雨林地区的人们常常受到与威胁生物多样性同样的过程的影响。加深了解什么对当地人是重要的能够改善决策。明确询问什么对当地人是重要的,本文调查了这种询问的作用。我们所用的例子来源于东加里曼丹(印度尼西亚婆罗洲)的生物多样性调查。我们与当地社区合作重点描述了当地看重的生境、物种和地点的特征以及它们的重要性。这个过程明确了不同的优先权和威胁,对管理的完善和权限提出了建议,指出了必要的特别行动、进一步调查或两者都需要做的问题。研究还表明了在当地人的引导下生物评价更为有效,并且揭示了当地社区与那些保护参与者合作的潜力。这样的评价是推动当地利益进入更高水平决策的第一步。结合当地观点的环保人士能够得到更广泛的支持以及有效保护的新机会。 | Douglas Sheil Rafindra Puri Meilinda Wan Miriam Van Heist Nining Liswanti Rukmiyati Ike Rachmatika Ismayadi Samsoedin 丁莉(译) | 2006 | AMBIO-人类环境杂志2006,35,1: | 3 |
| 3 | Serial therapies oriented by surgery for large primary liver carcinoma显示文摘Objective: To discuss the methods and effects of serialtherapies oriented by surgery in the treatment of pri-mary large liver cancers.Methods: From January 1993 to June 1999, 191 pa-tients with large liver carcinoma were treated surgi-cally. The size of tumors varied from 5.2 to 19.7 cm(mean 9.4 cm). Several types of liver resectionswere made in 121 patients and as a supplement, cry-osurgery was carried out for the remaining 70 pa-tients. Importable drug delivery system was institu-ted intraoperatively. Transcatheter arterial chemo-embolization (THP 30-60 mg, E-ADM 20-40 mg,CDDP 40-80 mg, MMC 10-20 mg, iodin oil 5-30ml), percutaneous ethanol injection, bioimmunother-apy and traditional Chinese medicine were used pre-and post-operatively. CT angiography and CT dur-ing arterial portography were used to find satellitenodules. Early stage recurrences were predicted byAFPmRNA in peripheral blood. Child-Pugh’s classi-fication plus branch chain amino acid/aromatic ami-no acid ratio (BCAA/AAA) was adopted in evalua-ting pre-operative liver functions.Results: Marked results were observed after serialtreatments oriented by surgery. The 1-, 3- and 5-year survival rates in resection group were 75.8 %,45.6% and 30.4%. respectively. The 1- and 3-yearsurvival rates in cryosurgery group were 63.2 % and37.0 %. The operative mortality was 1.57 %. Recur-rence rates were 69.2 % in AFPmRNA positive groupand 33.3% in AFPmRNA negative group (P<0.05). The BCAA/AAA ratio was lower than 1.5 intwo patients who died of hepatic failure after resec-tion.Conclusions: Serial treatments with surgery as thechief modality gives satisfactory results in patientswith large primary liver carcinoma. This regimenshould be regarded as a main strategy to deal withlarge liver carcinoma. AFPmRNA in the peripheralblood, signifying a recurrence, may become a newclinical parameter. The BCAA/AAA ratio plusChild-Pugh’s classification is able to evaluate moreaccurately liver function reserve before surgery. | Jing-An Rui Shao-Bin Wang Shu-Guang Chen Li Zhou Xue Wei Kai Han Nine Zhang Hai-Tao Zhao Xin Yang the Department of Liver Surgery Peking Union Medical College Hospital, Beijing 100032, China | 2002 | Hepatobiliary & Pancreatic Diseases International2002,1,3: | 2 |
| 4 | A Single-Base Mutation in the Peroxisome Proliferator-Activated Receptor γ4 Promoter Associated with Altered in Vitro Expression and Partial Lipodystrophy显示文摘 | Khalid Al-Shali Henian Cao Nine Knoers Ad R. Hermus Cees J. Tack Robert A. Hegele | 2004 | The Journal of Clinical Endocrinology & Metabolism2004,,11: | 1 |
| 5 | Inherited forms of renal hypomagnesemia: an update显示文摘 | Nine V. A. M. Knoers | 2009 | Pediatric Nephrology2009,,4: | 1 |
| 6 | Synthesis of a grapheneetungsten composite with improved dispersibility of graphene in an ethanol solution and its use as a counter electrode for dye-sensitised solar cells显示文摘 | Munkhbayar B Nine M J Jeoun J | 2013 | J Power Sources2013,230,: | 1 |
| 7 | A New Oligostilbene from the Roots of Vitis Amurensis显示文摘A new resveratrol trimer. amurensin G (1). was isolated from the roots of Vitisamurensis Rupr.Its structure and relative configuration were established on the basis of spectralevidence. especially on HMBC spectrum and NOE difference experiments. | Kai Sheng HUANG Mao LIN Lin Nine YU Man KONG(Institute of Materia Mad ica. Chinese Academy of Medical Sciencesand Peking Union Medical College. Beijing 10000) | 1999 | Chinese Chemical Letters1999,10,9: | 1 |
| 8 | Congenital nephrogenic diabetes insipidus : the current state of affairs 显示文摘 | Daniel W Peter MTD Nine VAM | 2012 | Pediatr Nephrol2012,27,12: | 1 |
| 9 | Forest management and public perceptions - visual versus verbal information 显示文摘 | Liisa Tahvanainen Liisa Tyrvainen Marjut Ihalainen Nine Vuorela Osmo Kolehmainen | 2001 | Landscape and Urban Planning2001,53,14: | 1 |
| 10 | Analysis and design of - switch direct AC - AC converters显示文摘 | Alesina A Venturini M G optimum - amplitude nine B | 1989 | IEEE Transactions on Power Electronics1989,4,1: | 1 |
| 11 | The applicability of coulomb's friction law to drawbeads in sheet metal forming 显示文摘 | Nine H D | 1982 | Journal of Applied Metal-working1982,2,3: | 1 |
| 12 | New drawbead concepts for sheet metal forming 显示文摘 | Nine H D | 1982 | Journal of Applied Metalworking1982,2,3: | 1 |
| 13 | PORT meta-analysis trialists group显示文摘 | Postoperative radiotherapy in non-small-cell lung cancer:Systematic review and meta-analysis of individual patient data from nine randomised controlled trials | 1998 | Lancet1998,352,9124: | 1 |
| 14 | How realistic are older drivers : rat- ings of their driving ability? 显示文摘 | Horswill Mark S Sullivan Karen Lurie-Beck Ja- nine K | 2013 | Accident Analysis and Prevention2013,50,1: | 1 |
| 15 | Tissue plasminogen actiovator for acute ischemic stroke显示文摘 | The NINES rt-PA Stroke Group | 1995 | New Engl J Mid1995,333,24: | 1 |
| 16 | Perillyl alcohol as a chemopreventive agent in N-nitrosomethyl-venzylamine-inducedrat esophageal tumorigenesis显示文摘 | LISTON B W NINES R CARLTON P S | 2003 | Cancer Res2003,63,10: | 1 |
| 17 | Perillyi alcohol as a chemopreventive agent in N-nitrosometylbenzylamine-induced rat esophageal tumorigenesis 显示文摘 | Liston B W Nines R Carlton P S | 2003 | Cancer Res2003,63,: | 1 |
| 18 | Rare inherited kidney diseases : challenges, opportunities, and perspectives 显示文摘 | Devuyst O Knoers Nine VAM Remuzzi G | 2014 | Lancet2014,383,9931: | 1 |
| 19 | Integrating the Accreditation Council for Graduate Medical Education general competencies into forensic pathology fellowship training显示文摘 | Zumwalt RE | 2005 | Am J Forensic Med and Pathol2005,26,4: | 1 |
| 20 | Gene therapy that inhibits nuclear translocation of nuclear factor kB results in tumor necrosis factor a induced apoptosis of human synovial fibroblasts 显示文摘 | Huang GZ Nine H Liu DI | 2000 | Arthritis Rheum2000,43,5: | 1 |