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您的检索式：作者名="Nicholas Delihas"
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| 1 | High sensitivity of Mycobacterium species to the bactericidal activity by polylysine显示文摘 | Nicholas Delihas Lee W. Riley Winnie Loo Jonathan Berkowitz Natalia Poltoratskaia | 1995 | FEMS Microbiology Letters1995，，3： | 1 |
| 2 | Discovery and characterization of the first non-coding RNA that regulates gene expression,micF RNA:A historical perspective显示文摘The first evidence that RNA can function as a regulator of gene expression came from experiments with prokaryotes in the 1980 s. It was shown that Escherichia coli micF isan independent gene,has its own promoter,and encodes a small non-coding RNA that base pairs with and inhibits translation of a target messenger RNA in response to environmental stress conditions. The mic F RNA was isolated,sequenced and shown to be a primary transcript. In vitro experiments showed binding to the target ompF mR NA. Secondary structure probing revealed an imperfect micF RNA/ompF RNA duplex interaction and the presence of a non-canonical base pair. Several transcription factors,including OmpR,regulate micF transcription in response to environmental factors. micF has also been found in other bacterial species,however,recently Gerhart Wagner and J?rg Vogel showed pleiotropic effects and found micF inhibits expression of multiple target mR NAs; importantly,one is the global regulatory gene lrp. In addition,micF RNA was found to interact with its targets in different ways; it either inhibits ribosome binding or induces degradation of the message. Thus the concept and initial experimental evidence that RNA can regulate gene expression was born with prokaryotes. | Nicholas Delihas | 2015 | World Journal of Biological Chemistry2015，6，4： | 1 |
| 3 | High sensitivity of Mycobacterium species to the bactericidal activity by polylysine显示文摘 | Nicholas Delihas Lee W. Riley Winnie Loo Jonathan Berkowitz Natalia Poltoratskaia | 1995 | FEMS Microbiology Letters1995，，3： | 1 |
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