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8篇 您的检索式:作者名="Nicholas Carroll"
    题名 作者 年代 出处 被引量
1Endoscopic Ultrasound-guided drainage of an abdominal fluid collection following Whipple's resection显示文摘Percutaneous aspiration and drainage of post-operative abdominal fluid collections is a well established standard technique. However,some fluid collections are not amenable to percutaneous drainage either due to location or the presence of surrounding visceral structures. Endoscopic Ultrasound (EUS) has been widely used for the drainage of pancreatitis-related abdominal fluid collections. However,there are no reports on the use of this technique in the post-operative setting. We report a case where the EUS-guided technique was used to drain a percutaneously inaccessible post-operative collection which had developed after Whipple's resection.Asif Jah Neville Jamieson Emmanuel Huguet William Griffi ths Nicholas Carroll Raaj Praseedom 2008World Journal of Gastroenterology2008,14,44:3
2The determination of glycogenin live rand muscle by use of athrone reagent显示文摘Nicholas V Carroll Robert W The Journalof Biologicalchemistry0,,:1
3Some effects of substrate roughness on wettability显示文摘Hitchcock S J Carroll N T Nicholas M G 1981Journal of Materials Science1981,16,3:1
4Integration of solid phase extraction with HILIC-MS/MS for analysis of free amino acids in source water显示文摘Amino acids(AAs) are prevalent in source water, particularly during spring run-off. Monitoring of amino acids in source water is desirable for water treatment plants(WTP) to indicate changes in source water quality. The objective of this study was to establish analytical procedures for reliable monitoring of amino acids in source water. Therefore, we examined two different methods, large volume inject(LVI) and solid phase extraction(SPE), for sample preparation prior to HILIC-MS/MS. The LVI-HILIC-MS/MS method can provide fast and sensitive detection for clean samples, but suffers from matrix effects, resulting in irreproducible separation and shortening column lifetime. We have demonstrated that SPE was necessary prior to HILIC-MS/MS to achieve reproducible and reliable quantification of AAs in source water. A natural heterocyclic amine 1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid(MTCCA) was also included in the method to indicate changes in other natural nitrogenous compounds in source water. The SPE-HILIC-MS/MS method was able to achieve limits of detection from 2.6-3400 ng/L for the amino acids and MTCCA with RSDs( n = 3) of 1.1%-4.8%. As well, retention times(RT) of the analytes were reproducible with variation less than 0.01 min( n = 3) through the entire project. We further applied the SPE-HILICMS/MS method to determine AAs in authentic source water samples collected from two drinking water treatment plants(WTPs) during the 2021 spring run-off season. The results support that the SPE-HILIC-MS/MS method does not require derivatization and can provide reliable, accurate, and robust analysis of AAs and MTCCA in source water, supporting future monitoring of source water quality.Junlang Qiu Caley Craven Nicholas Wawryk Kristin Carroll Xing-Fang Li 2022Journal of Environmental Sciences2022,34,7:1
5The determination of glycogen in liver and muscle by use of athrone reagent显示文摘Nicholas V Carroll & Robert W The journal of Biological chemistry0,,:1
6Pockmark development in the Petrel Sub-basin, Timor Sea, Northern Australia: Seabed habitat mapping in support of CO2 storage assessments 显示文摘Nicholas W A Nichol S L Howard F J F Picard K Duller H Radke L C Carroll A G Tran M Siwabessy PJW 2014Continent Shelf Res2014,83,:1
7Acute gastric necrosis and air in the hepatic-portal vein secondary to a strangulated paraumbilical hernia显示文摘Amin Oomatia Nicholas Carroll Peter M Safranek 2013The Lancet2013,,:1
8HDPairFinder:A data processing platform for hydrogen/deuterium isotopic labeling-based nontargeted analysis of trace-level amino-containing chemicals in environmental water显示文摘The combination of hydrogen/deuterium(H/D)formaldehyde-based isotopic methyl labeling with solid-phase extraction and high-performance liquid chromatography–high resolution mass spectrometry(HPLC-HRMS)is a powerful analytical solution for nontargeted analysis of trace-level amino-containing chemicals in water samples.Given the huge amount of chemical information generated in HPLC-HRMS analysis,identifying all possible H/Dlabeled amino chemicals presents a significant challenge in data processing.To address this,we designed a streamlined data processing pipeline that can automatically extract H/D-labeled amino chemicals from the raw HPLC-HRMS data with high accuracy and efficiency.First,we developed a cross-correlation algorithm to correct the retention time shift resulting from deuterium isotopic effects,which enables reliable pairing of H-and D-labeled peaks.Second,we implemented several bioinformatic solutions to remove false chemical features generated by in-source fragmentation,salt adduction,and natural13C isotopes.Third,we used a data mining strategy to construct the AMINES library that consists of over 38,000 structure-disjointed primary and secondary amines to facilitate putative compound annotation.Finally,we integrated these modules into a freely available R program,HDPairFinder.R.The rationale of each module was justified and its performance tested using experimental H/D-labeled chemical standards and authentic water samples.We further demonstrated the application of HDPairFinder to effectively extract N-containing contaminants,thus enabling the monitoring of changes of primary and secondary N-compounds in authentic water samples.HDPairFinder is a reliable bioinformatic tool for rapid processing of H/D isotopic methyl labeling-based nontargeted analysis of water samples,and will facilitate a better understanding of N-containing chemical compounds in water.Tingting Zhao Kristin Carroll Caley B.Craven Nicholas J.P.Wawryk Shipei Xing Jian Guo Xing-Fang Li Tao Huan 2024Journal of Environmental Sciences2024,,2:0
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