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您的检索式：作者名="Neil M Ferguson"
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| 1 | Portal hypertension in polycystic liver disease patients does not affect wait-list or immediate post-liver transplantation outcomes显示文摘AIM To establish the impact of portal hypertension(PH) on wait-list/post-transplant outcomes in patients with polycystic liver disease(PCLD) listed for liver transplantation. METHODS A retrospective single-centre case controlled study of consecutive patients listed for liver transplantation over 12 years was performed from our centre. PH in the PCLD cohort was defined by the one or more of following parameters:(1) presence of radiological or endoscopic documented varices from our own centre or the referral centre;(2) splenomegaly(> 11 cm) on radiology inabsence of splenic cysts accounting for increased imaging size;(3) thrombocytopenia(platelets < 150 × 109/L); or(4) ascites without radiological evidence of hepatic venous outflow obstruction from a single cyst. RESULTS Forty-seven PCLD patients(F: M = 42: 5) were listed for liver transplantation(LT)(single organ, n = 35; combined liver-kidney transplantation, n = 12) with 19 patients(40.4%) having PH. When comparing the PH group with non-PH group, the mean listing age(PH group, 50.6(6.4); non-PH group, 47.1(7.4) years; P = 0.101), median listing MELD(PH group, 12; non-PH group, 11; P = 0.422) median listing UKELD score(PH group, 48; non-PH group, 46; P = 0.344) and need for renal replacement therapy(P = 0.317) were similar. In the patients who underwent LT alone, there was no difference in the duration of ICU stay(PH, 3 d; non-PH, 2 d; P = 0.188), hospital stay length(PH, 9 d; non-PH, 10 d; P = 0.973), or frequency of renal replacement therapy(PH, 2/8; non-PH, 1/14; P = 0.121) in the immediate post-transplantation period. CONCLUSION Clinically apparent portal hypertension in patients with PCLD listed for liver transplantation does not appear to have a major impact on wait-list or peri-transplant morbidity. | Neil Rajoriya Dhiraj Tripathi Joanna A Leithead Bridget K Gunson Sophie Lord James W Ferguson Gideon M Hirschfield | 2016 | World Journal of Gastroenterology2016，22，45： | 2 |
| 2 | Epidemic and intervention modelling - a scientific rationale for policy decisions? Lessons from the 2009 influenza pandemic显示文摘 | Kerkhove Maria D Van Ferguson Neil M | 2012 | EN2012，，4： | 1 |
| 3 | 传染病流行的数学预测显示文摘传染病流行是疾病在人群中传播的连锁反应。由于疾病在人群中流行的过程相对简单,所以有时可以用数学模型来描述甚至预测。所谓“简单”是指感染和疾病进展以个体从一种状态转变成另一种状态为特征。例如,从未感染或易感状态转变为感染状态,或从接触感染者转变为感染状态,或因感染恢复并且获得免疫力由感染期转入恢复期。因此,模型的建立将包括个体感染状态的分类以及导致感染状态相互转变的过程。建立预测模型的目的旨在预测随着时间的推移,不同人群所占比例的变化以及疾病相关事件的发生率。本文着重讨论了疾病流行的数学模型,但类似的方法也可用于对感染者病毒或细菌感染发病机制的研究。 | Neil M Ferguson 朱卫国(译) 盛瑞媛(校) | 2006 | 国际内科双语杂志(中英文)2006，6，3： | 0 |
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